Patents by Inventor Brett E. Lomenick

Brett E. Lomenick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODRUGS OF ALPHA-KETOGLUTARATE, ALPHA-KETOBUTYRATE, ALPHA-KETOISOVALERATE, AND ALPHA-KETOISOHEXANOATE, AND USES THEREOF
    Publication number: 20230174500
    Abstract: The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.
    Type: Application
    Filed: November 9, 2022
    Publication date: June 8, 2023
    Inventors: Michael E. Jung, Jing Huang, Yanpeng Xing, Brett E. Lomenick, Min Chai, Xudong Fu
  • Prodrugs of alpha-ketoglutarate, alpha-ketobutyrate, alpha-ketoisovalerate, and alpha-ketoisohexanoate, and uses thereof
    Patent number: 11524948
    Abstract: The present disclosure provides compounds of Formula (VIA), Formula (IIIA), Formula (IVA), and Formula (VA). The compounds are prodrugs of alpha-ketoglutarate, alpha-ketobutryrate, alpha-ketoisovalerate, and alpha-ketoisohexanoate, which are useful in treating or preventing age related diseases, disorders, or conditions.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: December 13, 2022
    Assignee: The Regents of the University of California
    Inventors: Michael E. Jung, Jing Huang, Yanpeng Xing, Brett E. Lomenick, Min Chai, Xudong Fu
  • PRODRUGS OF ALPHA-KETOGLUTARATE, ALPHA-KETOBUTYRATE, ALPHA-KETOISOVALERATE, AND ALPHA-KETOISOHEXANOATE, AND USES THEREOF
    Publication number: 20200325113
    Abstract: The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.
    Type: Application
    Filed: June 30, 2020
    Publication date: October 15, 2020
    Inventors: Michael E. Jung, Jing Huang, Yanpeng Xing, Brett E. Lomenick, Min Chai, Xudong Fu
  • Ketobutyrate compounds and compositions for treating age-related symptoms and diseases
    Patent number: 10729668
    Abstract: Disclosed herein are methods for (a) treating, inhibiting, or reducing aging of a subject, (b) treating, inhibiting, or reducing an age-related symptom or an age-related disease in a subject, and/or (c) increasing the lifespan of a subject which comprise administering to the subject one or more ketobutyrate compounds and compositions thereof.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: August 4, 2020
    Assignee: The Regents of the University of California
    Inventors: Jing Huang, Randall M. Chin, Xudong Fu, Heejun Hwang, Karen Reue, Laurent Vergnes, Meisheng Jiang, Brett E. Lomenick, Xiang Yin, Mansoureh Eghbali, Jingyuan Li, Samuel Wheeler French, Ronik Khachatoorian
  • Ketobutyrate Compounds and Compositions for Treating Age-Related Symptoms and Diseases
    Publication number: 20170128395
    Abstract: Disclosed herein are methods for (a) treating, inhibiting, or reducing aging of a subject, (b) treating, inhibiting, or reducing an age-related symptom or an age-related disease in a subject, and/or (c) increasing the lifespan of a subject which comprise administering to the subject one or more ketobutyrate compounds and compositions thereof.
    Type: Application
    Filed: June 29, 2015
    Publication date: May 11, 2017
    Inventors: Jing Huang, Randall M. Chin, Xudong Fu, Heejun Hwang, Karen Reue, Laurent Vergnes, Meisheng Jiang, Brett E. Lomenick, Xiang Yin, Mansoureh Eghbali, Jingyuan Li, Samuel Wheeler French, Ronik Khachatoorian
  • Compositions and Methods for Treating Aging and Age-Related Diseases and Symptoms
    Publication number: 20160354334
    Abstract: Disclosed herein are methods for (a) inhibiting, reducing, slowing, or preventing, the aging of a subject, (b) for treating, inhibiting, reducing, or preventing an age-related disease in the subject, and/or (c) for increasing the lifespan of the subject which comprise administering to the subject one or more glutamate compounds, such as ?-ketoglutate, and/or one or more glutamate compounds, such as 2-hydroxypentanedioate, and compositions thereof.
    Type: Application
    Filed: February 11, 2015
    Publication date: December 8, 2016
    Inventors: Jing Huang, Randall Chin, Simon Diep, Melody Y. Pai, Brett E. Lomenick, Xudong Fu, Karen Reue, Laurent Vergnes, Michael E. Jung, Gang Deng, Heejun Hwang, Meisheng Jiang