Patents by Inventor Brett Hirsch

Brett Hirsch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antigen analogue for calibration of immunometric diagnostic assays
    Patent number: 12123875
    Abstract: An antigen with an increased half-life is provided for the formulation of more stable and consistent clinical diagnostic immunoassay controls and calibrators. An antigen analogue comprises a first and a second polypeptide which is identical or similar to corresponding terminal amino acid sequences of an antigen. The first and second polypeptides are connected with a PEG chain. Also provided are methods of calibrating assays using a compound disclosed herein.
    Type: Grant
    Filed: June 14, 2022
    Date of Patent: October 22, 2024
    Assignee: Ortho Clinical Diagnostics, Inc.
    Inventors: Brett Hirsch, Jian Zheng, Stephen Daggett
  • ANTIGEN ANALOGUE FOR IMMUNOMETRIC DIAGNOSTIC ASSAYS AND METHOD OF USE THEREOF
    Publication number: 20220404358
    Abstract: An antigen with an increased half-life is provided for the formulation of more stable and consistent clinical diagnostic immunoassay controls and calibrators. An antigen analogue comprises a first and a second polypeptide which is identical or similar to corresponding terminal amino acid sequences of an antigen. The first and second polypeptides are connected with a PEG chain. Also provided are methods of calibrating assays using a compound disclosed herein.
    Type: Application
    Filed: June 14, 2022
    Publication date: December 22, 2022
    Applicant: ORTHO-CLINICAL DIAGNOSTICS, INC.
    Inventors: Brett HIRSCH, Jian ZHENG, Stephen Daggett
  • LITHIUM HEPARIN AS A BLOCKING AGENT
    Publication number: 20220178914
    Abstract: Described herein are blocking agents that can be used in diagnostic assays to prevent false positive results.
    Type: Application
    Filed: December 1, 2021
    Publication date: June 9, 2022
    Inventors: Brett Hirsch, Paul Contestable