Abstract: The present disclosure provides pharmaceutical compositions comprising i) a MsP1 enzyme and ii) one or more pharmaceutically acceptable carriers. The disclosure also provides methods comprising the pharmaceutical compositions for use in treating patients with various disease states, as well as related sequences and expression vectors.

Abstract: An agricultural stalk sensor, having at least a first wand comprising a first rib extending longitudinally along a first side of the first wand. The stalk sensor optionally having a second wand comprising a second rib extending longitudinally along a first side of the second wand. A stalk sensor system wherein the first rib and the second rib at least partially overlap when the first wand and the second wand are in a resting position.

Abstract: The disclosure is related to an assisted steering unit. In various implementations the assisted steering unit includes a motor drive unit and a ring assembly constructed and arranged to couple to and rotate a steering wheel. The assisted steering unit may include a ring assembly where the ring assembly includes a housing, a ring gear disposed within the housing, an anti-rotation pin operatively engaged with the housing. The assisted steering unit may also include a motor drive unit (MDU) including a motor and a drive gear rotatably engaged with the motor. The ring assembly and motor drive unit are constructed and arranged to be releasably engaged to each other.

Abstract: An exchange computer system includes: at least one communication interface; a crossing facility configured to perform operations of: retrieving portfolio data encoding asset positions, a current measurement of capital efficiency, and participant-configured transaction portfolio attributes for at least two participants, wherein the participant-configured transaction portfolio attributes comprise a goal of capital efficiency, a transaction cost limit, and portfolio limits for each of the at least two participants; and performing a crossing operation between the portfolios of two of the at least two participants so that the at least two participants can each set and forget the respective transaction portfolio attributes by: based on the portfolio data of the two participants, identifying a network of single-leg transactions; and in response to determining that executing the network of single-leg transactions would not violate the transaction cost limit and the portfolio limits of each participant, executing the

Abstract: A stalk sensing system, comprising a bracket, sensor shell configured to be mounted to the bracket, a sensor configured for insertion into the sensor shell, a wand configured to be mounted to the sensor shell, and one or more anti-rotation features. The harvester and stalk sensing system may also into one or more board holding features and, optionally, a crop divertor(s).

Abstract: Systems and methods for transforming and navigating historical map images are presented. The systems and methods embodiments facilitate providing, searching for, retrieving, transforming, and/or navigating a historical map image vis-à-vis a modern location and/or map. A map interface facilitates automatedly overlaying, annotating, and aligning a historical map image(s) with a modern map, allowing a user to search for a location and see the same in the historical map image, and change a visibility of the overlaid and aligned map images relative to each other. The map interface provides user interactions that facilitate retrieving, viewing, and manipulating records, historical districts, and other pertinent data through interacting with a particular location and/or searched-for individual, such as an ancestor or other person of interest.

Abstract: Systems and methods for transforming and navigating historical map images are presented. The systems and methods embodiments facilitate providing, searching for, retrieving, transforming, and/or navigating a historical map image vis-à-vis a modern location and/or map. A map interface facilitates automatedly overlaying, annotating, and aligning a historical map image(s) with a modern map, allowing a user to search for a location and see the same in the historical map image, and change a visibility of the overlaid and aligned map images relative to each other. The map interface provides user interactions that facilitate retrieving, viewing, and manipulating records, historical districts, and other pertinent data through interacting with a particular location and/or searched-for individual, such as an ancestor or other person of interest.

Abstract: The assisted steering unit includes a motor drive unit and a ring assembly constructed and arranged to couple to and rotate a steering wheel. The assisted steering unit may include a ring assembly where the ring assembly includes a housing, a ring gear disposed within the housing, an anti-rotation pin operatively engaged with the housing. The assisted steering unit may also include a motor drive unit (MDU) including a motor and a drive gear rotatably engaged with the motor. The ring assembly and motor drive unit are constructed and arranged to be releasably engaged to each other.

Abstract: One variation of a system includes a chassis: defining a set of platform mounts defining a pivot axis; and a slot arranged between the set of platform mounts and configured to transiently retain a filter receptacle below the pivot axis. The system further includes a tray platform: pivotably coupled to the set of platform mounts; defining a tray-receiving section configured to receive a tray defining a fluid release point and configured to retain a volume of resin; and defining a set of supports arranged about the tray-receiving section and configured to locate the fluid release point at the fixed pivot location. The system further includes a tray lock coupled to the platform and configured to transiently generate a magnetic field to draw the tray against the tray-receiving section and cooperate with the set of tray supports to constrain the fluid release point to the fixed pivot location.

Abstract: A 3D printer includes a chamber configured to receive extruded material to print a part and a tool chamber above the chamber, the tool chamber comprising a viewing window and a tool rack. The 3D printer includes a plurality of print heads, each of the plurality of print heads residing in a docked position on the tool rack and when not in use. Each of the plurality of print heads comprising a illuminated status indicator configured to emit a plurality of signals indicative of a status or error of the print head or a status of the 3D printer, wherein the illuminated status indicator faces the viewing window and a plurality of sensors located on the print head or in the 3D printer and configured to detect a status of the print head or other printer components or an error in the print head or other printer components.

Abstract: One variation of a system includes a chassis: defining a set of platform mounts defining a pivot axis; and a slot arranged between the set of platform mounts and configured to transiently retain a filter receptacle below the pivot axis. The system further includes a tray platform: pivotably coupled to the set of platform mounts; defining a tray-receiving section configured to receive a tray defining a fluid release point and configured to retain a volume of resin; and defining a set of supports arranged about the tray-receiving section and configured to locate the fluid release point at the fixed pivot location. The system further includes a tray lock coupled to the platform and configured to transiently generate a magnetic field to draw the tray against the tray-receiving section and cooperate with the set of tray supports to constrain the fluid release point to the fixed pivot location.

Abstract: A stalk sensor comprising a first wand comprising a contact surface at a distal end, a first magnet disposed at a distal end of the first wand, a second wand comprising a contact surface at a distal end, and a second magnet disposed at a distal end of the second wand, the magnet configured to attract the first magnet and thereby the first wand into contact with the second wand at the contact surfaces with the second wand, wherein the first contact surface and the second contact surface are in contact when the stalk sensor is in a home position. The stalk sensor wherein the wands are self-aligning on horizontal and vertical axes.

Abstract: Systems and techniques are disclosed for reducing regulatory capital requirements for market participants with financial positions. Participant positions are received in a database for matching the participant positions. Additionally, participant assessed theoretical value by position, capital requirement reduction benefit for closing transactions and penalty for opening transactions by position, compression cost constraints, and zero or more custom constraints specifying acceptable risk profile in a portfolio of trades are received from each participant. A set of trades between a plurality of participants that delivers a capital requirement reduction to each of the plurality of participants, while simultaneously satisfying all participant specified cost and risk constraints is calculated. A time period to review and approve compression portfolios prior to consummating trades is provided.

Abstract: Systems and methods for transforming and navigating historical map images are presented. The systems and methods embodiments facilitate providing, searching for, retrieving, transforming, and/or navigating a historical map image vis-à-vis a modern location and/or map. A map interface facilitates automatedly overlaying, annotating, and aligning a historical map image(s) with a modern map, allowing a user to search for a location and see the same in the historical map image, and change a visibility of the overlaid and aligned map images relative to each other. The map interface provides user interactions that facilitate retrieving, viewing, and manipulating records, historical districts, and other pertinent data through interacting with a particular location and/or searched-for individual, such as an ancestor or other person of interest.

Abstract: A consumable assembly for supplying filament to a 3D printer having two or more receptacles having different geometric configurations, the 3D printer builds parts by material extrusion. The consumable assembly includes a container configured to retain a supply of a first filament, and a first filament guide tube having a length, the first filament guide tube having an inlet end attached to the first container and an outlet end, The consumable assembly includes a key having a geometric configuration allowing the key to be plugged into only one receptacle of the two or more receptacles of the 3D printer, the key comprising a conduit having an entrance and an exit, a coupling portion, and an engagement portion, wherein the entrance to the conduit is coupled to the outlet end of the first filament guide tube to thereby form a closed filament path from the first container to the 3D printer.