Patents by Inventor Brett Jordan
Brett Jordan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230243730Abstract: Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. A contrast pattern for autofocusing is provided on the flowcell, for example at an edge of a rear illumination opening. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and/or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Blood cell images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.Type: ApplicationFiled: April 11, 2023Publication date: August 3, 2023Inventors: Bart J. Wanders, Brett Jordan, Gregory A. Farrell, Thomas H. Adams, Warren Groner
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Publication number: 20230075298Abstract: Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. A contrast pattern for autofocusing is provided on the flowcell, for example at an edge of a rear illumination opening. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and/or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Blood cell images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.Type: ApplicationFiled: November 9, 2022Publication date: March 9, 2023Inventors: Bart J. Wanders, Brett Jordan, Gregory A. Farrell, Thomas H. Adams, Warren Groner
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Patent number: 11543340Abstract: Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. A contrast pattern for autofocusing is provided on the flowcell, for example at an edge of a rear illumination opening. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and/or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Blood cell images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.Type: GrantFiled: September 18, 2019Date of Patent: January 3, 2023Assignee: Iris International, Inc.Inventors: Bart J. Wanders, Brett Jordan, Gregory A. Farrell, Thomas H. Adams, Warren Groner
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Patent number: 10794900Abstract: The present disclosure relates to apparatus, systems, compositions, and methods for analyzing a sample containing particles. A particle imaging system or analyzer can include a flowcell through which a urine sample containing particles is caused to flow, and a high optical resolution imaging device which captures images for image analysis. A contrast pattern for autofocusing is provided on the flowcell. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and/or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Cell or particle images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.Type: GrantFiled: November 21, 2017Date of Patent: October 6, 2020Assignee: Iris International, Inc.Inventors: Bart J. Wanders, Eric Chapoulaud, Brett Jordan
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Patent number: 10705008Abstract: Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. A contrast pattern for autofocusing is provided on the flowcell, for example at an edge of a rear illumination opening. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and/or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Blood cell images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.Type: GrantFiled: March 17, 2014Date of Patent: July 7, 2020Assignee: Iris International, Inc.Inventors: Bart J. Wanders, Brett Jordan, Gregory A. Farrell, Thomas H. Adams, Warren Groner
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Publication number: 20200080926Abstract: Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. A contrast pattern for autofocusing is provided on the flowcell, for example at an edge of a rear illumination opening. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and/or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Blood cell images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.Type: ApplicationFiled: September 18, 2019Publication date: March 12, 2020Inventors: Bart J. Wanders, Brett Jordan, Gregory A. Farrell, Thomas H. Adams, Warren Groner
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Patent number: 10495561Abstract: Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. A contrast pattern for autofocusing is provided on the flowcell, for example at an edge of a rear illumination opening. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and/or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Blood cell images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.Type: GrantFiled: March 17, 2014Date of Patent: December 3, 2019Assignee: Iris International, Inc.Inventors: Bart J. Wanders, Brett Jordan, Gregory A. Farrell, Thomas H. Adams, Warren Groner
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Patent number: 10195483Abstract: An exercise system comprising: an exercise cycle comprising a crank, wherein the crank is configured to be rotated by a user; and a sensing unit coupled to the exercise cycle, wherein the sensing unit is configured to sense information related to at least one crank measurement and to transmit the information related to the at least one crank measurement to a remote device via wireless communication. In some embodiments, the remote device is a mobile device. In some embodiments, the at least one crank measurement comprises a rotational speed of the crank or a force applied to the crank. The remote device can display information related to use of the exercise cycle based on the information received from the exercise cycle.Type: GrantFiled: June 28, 2016Date of Patent: February 5, 2019Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: William J. Kaiser, Lawrence Au, Maxim A. Batalin, Alexander A. Bui, Bruce H. Dobkin, Xiaoyu Xu, Brett Jordan, Seth Thomas
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Patent number: 10060846Abstract: Aspects and embodiments of the instant disclosure provide a particle and/or intracellular organelle alignment agent for a particle analyzer used to analyze particles contained in a sample. An exemplary particle and/or intracellular organelle alignment agent includes an aqueous solution, a viscosity modifier, and/or a buffer. Embodiments also encompass systems, compositions, and methods for analyzing a sample containing particles. Parrticles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed, for example using certain focusing techniques, into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. Blood cell images can be collected and analyzed using dynamic range extension processes and systems.Type: GrantFiled: July 10, 2017Date of Patent: August 28, 2018Assignee: Iris International, Inc.Inventors: Bart J. Wanders, Gregory A. Farrell, Thomas H. Adams, Warren Groner, Xiaodong Zhao, Brett Jordan, Jack Cremins, Carol Quon
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Publication number: 20180143182Abstract: The present disclosure relates to apparatus, systems, compositions, and methods for analyzing a sample containing particles. A particle imaging system or analyzer can include a flowcell through which a urine sample containing particles is caused to flow, and a high optical resolution imaging device which captures images for image analysis. A contrast pattern for autofocusing is provided on the flowcell. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and/or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Cell or particle images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.Type: ApplicationFiled: November 21, 2017Publication date: May 24, 2018Applicant: Iris International, Inc.Inventors: Bart J. Wanders, Eric Chapoulaud, Brett Jordan
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Patent number: 9857361Abstract: The present disclosure relates to apparatus, systems, compositions, and methods for analyzing a sample containing particles. A particle imaging system or analyzer can include a flowcell through which a urine sample containing particles is caused to flow, and a high optical resolution imaging device which captures images for image analysis. A contrast pattern for autofocusing is provided on the flowcell. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and/or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Cell or particle images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.Type: GrantFiled: March 17, 2014Date of Patent: January 2, 2018Assignee: IRIS International, Inc.Inventors: Bart J. Wanders, Eric Chapoulaud, Brett Jordan
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Publication number: 20170370820Abstract: Aspects and embodiments of the instant disclosure provide a particle and/or intracellular organelle alignment agent for a particle analyzer used to analyze particles contained in a sample. An exemplary particle and/or intracellular organelle alignment agent includes an aqueous solution, a viscosity modifier, and/or a buffer. Embodiments also encompass systems, compositions, and methods for analyzing a sample containing particles. Parrticles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed, for example using certain focusing techniques, into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. Blood cell images can be collected and analyzed using dynamic range extension processes and systems.Type: ApplicationFiled: July 10, 2017Publication date: December 28, 2017Applicant: Iris International, Inc.Inventors: Bart J. Wanders, Gregory A. Farrell, Thomas H. Adams, Warren Groner, Xiaodong Zhao, Brett Jordan, Jack Cremins, Carol Quon
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Patent number: 9702806Abstract: Aspects and embodiments of the instant disclosure provide a particle and/or intracellular organelle alignment agent for a particle analyzer used to analyze particles contained in a sample. An exemplary particle and/or intracellular organelle alignment agent includes an aqueous solution, a viscosity modifier, and/or a buffer. Embodiments also encompass systems, compositions, and methods for analyzing a sample containing particles. Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed, for example using certain focusing techniques, into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. Blood cell images can be collected and analyzed using dynamic range extension processes and systems.Type: GrantFiled: March 18, 2014Date of Patent: July 11, 2017Assignee: Iris International, Inc.Inventors: Bart J. Wanders, Gregory A. Farrell, Thomas H. Adams, Warren Groner, Xiaodong Zhao, Brett Jordan, Jack Cremins, Carol Quon
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Publication number: 20160303427Abstract: An exercise system comprising: an exercise cycle comprising a crank, wherein the crank is configured to be rotated by a user; and a sensing unit coupled to the exercise cycle, wherein the sensing unit is configured to sense information related to at least one crank measurement and to transmit the information related to the at least one crank measurement to a remote device via wireless communication. In some embodiments, the remote device is a mobile device. In some embodiments, the at least one crank measurement comprises a rotational speed of the crank or a force applied to the crank. The remote device can display information related to use of the exercise cycle based on the information received from the exercise cycle.Type: ApplicationFiled: June 28, 2016Publication date: October 20, 2016Applicant: The Regents of the University of CaliforniaInventors: William J. Kaiser, Lawrence Au, Maxim A. Batalin, Alexander A. Bui, Bruce H. Dobkin, Xiaoyu Xu, Brett Jordan, Seth Thomas
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Patent number: 9403053Abstract: An exercise system comprising: an exercise cycle comprising a crank, wherein the crank is configured to be rotated by a user; and a sensing unit coupled to the exercise cycle, wherein the sensing unit is configured to sense information related to at least one crank measurement and to transmit the information related to the at least one crank measurement to a remote device via wireless communication. In some embodiments, the remote device is a mobile device. In some embodiments, the at least one crank measurement comprises a rotational speed of the crank or a force applied to the crank. The remote device can display information related to use of the exercise cycle based on the information received from the exercise cycle.Type: GrantFiled: May 25, 2012Date of Patent: August 2, 2016Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: William J. Kaiser, Lawrence Au, Maxim A. Batalin, Alexander A. Bui, Bruce H. Dobkin, Xiaoyu Xu, Brett Jordan, Seth Thomas
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Patent number: 9329173Abstract: An aptamer-based solid-state electrochemical biosensor for label-free detection of Salmonella enterica serovars utilizing immobilized aptamers. The device is realized by forming a matrix array of parallel capacitors, thus allowing the realization of low-cost, portable, fully integrated devices. Protein-aptamer binding modulates the threshold voltage of a circuit, changing the impedance (capacitance) of the circuit. This circuit is further characterized by an electrode coded with a p-Si substrate, enhancing the affinity between the Salmonella outer membrane proteins (OMPs) and the aptamer. An aptamer embedded detection plate is configured within a testing lid device that fits a standard, commercially available polymer specimen jar. A sample is mixed with broth for incubation and cultivation of any present Salmonella bacteria to obtain acceptable concentration of the pathogen for testing. The information obtained can then be transmitted by wireless network.Type: GrantFiled: January 7, 2010Date of Patent: May 3, 2016Assignee: Sensor-Kinesis CorporationInventors: Yehoshua Shachar, Winston Wu, Thomas Chen, Leslie Farkas, Brett Jordan, Paladin Luboff, Herwin Chan, Kyle Zimmerman
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Patent number: 9310363Abstract: An aptamer-based solid-state electrochemical biosensor for label-free detection of Salmonella enterica serovars utilizing immobilized aptamers. The device is realized by forming a matrix array of parallel capacitors, thus allowing the realization of low-cost, portable, fully integrated devices. Protein-aptamer binding modulates the threshold voltage of a circuit, changing the impedance (capacitance) of the circuit. This circuit is further characterized by an electrode coded with a p-Si substrate, enhancing the affinity between the Salmonella outer membrane proteins (OMPs) and the aptamer. An aptamer embedded detection plate is configured within a testing lid device that fits a standard, commercially available polymer specimen jar. A sample is mixed with broth for incubation and cultivation of any present Salmonella bacteria to obtain acceptable concentration of the pathogen for testing. The information obtained can then be transmitted by wireless network.Type: GrantFiled: April 21, 2010Date of Patent: April 12, 2016Assignee: Sensor-Kinesis CorporationInventors: Yehoshua Shachar, Winston Wu, Thomas Chen, Leslie Farkas, Brett Jordan, Paladin Luboff, Herwin Chan, Kyle Zimmerman
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Publication number: 20160041083Abstract: Aspects and embodiments of the instant disclosure provide a particle and/or intracellular organelle alignment agent for a particle analyzer used to analyze particles contained in a sample. An exemplary particle and/or intracellular organelle alignment agent includes an aqueous solution, a viscosity modifier, and/or a buffer. Embodiments also encompass systems, compositions, and methods for analyzing a sample containing particles. Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed, for example using certain focusing techniques, into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. Blood cell images can be collected and analyzed using dynamic range extension processes and systems.Type: ApplicationFiled: March 18, 2014Publication date: February 11, 2016Inventors: Bart J. WANDERS, Gregory A. FARRELL, Thomas H. ADAMS, Warren GRONER, Xiaodong ZHAO, Brett JORDAN, Jack CREMINS, Carol QUON
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Publication number: 20140329265Abstract: The present disclosure relates to apparatus, systems, compositions, and methods for analyzing a sample containing particles. A particle imaging system or analyzer can include a flowcell through which a urine sample containing particles is caused to flow, and a high optical resolution imaging device which captures images for image analysis. A contrast pattern for autofocusing is provided on the flowcell. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and/or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Cell or particle images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.Type: ApplicationFiled: March 17, 2014Publication date: November 6, 2014Applicant: IRIS International, Inc.Inventors: Bart J. Wanders, Eric Chapoulaud, Brett Jordan
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Patent number: D929674Type: GrantFiled: January 30, 2020Date of Patent: August 31, 2021Inventor: Brett Jordan McNay