Patents by Inventor Brett Neilan

Brett Neilan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes to make neosaxitoxin and analogues thereof
    Patent number: 11566271
    Abstract: The present invention relates to processes to make neosaxitoxin, and analogues and variants thereof, and intermediates in the production of neosaxitoxin in recombinant host cells. Neosaxitoxin and the analogues and variants thereof may be used in the production of pharmaceutical compositions.
    Type: Grant
    Filed: October 19, 2020
    Date of Patent: January 31, 2023
    Assignees: Vestlandets Innovasjonsseiskap AS, Newsouth Innovations Pty Limited
    Inventors: Ralf Kellmann, Brett Neilan
  • Recombinant microcystin production
    Patent number: 11130784
    Abstract: The present invention relates generally to methods for producing microcystin and recombinant cells capable of producing microcystin. The recombinant cells express exogenous microcystin synthase polypeptides under the control of an exogenous promoter, and further express an exogenous phosphopantethienyl transferase (PPTase). The present invention further relates to microcystin as produced in recombinant cells by the methods described herein.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: September 28, 2021
    Assignee: NewSouth Innovations Pty Ltd
    Inventors: Brett Neilan, Tianzhe Liu, Rabia Mazmouz, Sarah Ongley
  • PROCESS
    Publication number: 20210108239
    Abstract: The present invention relates to processes to make neosaxitoxin, and analogues and variants thereof, and intermediates in the production of neosaxitoxin in recombinant host cells. Neosaxitoxin and the analogues and variants thereof may be used in the production of pharmaceutical compositions.
    Type: Application
    Filed: October 19, 2020
    Publication date: April 15, 2021
    Inventors: Ralf Kellmann, Brett Neilan
  • Process
    Patent number: 10920256
    Abstract: The present invention relates to processes to make neosaxitoxin, and analogues and variants thereof, and intermediates in the production of neosaxitoxin in recombinant host cells. Neosaxitoxin and the analogues and variants thereof may be used in the production of pharmaceutical compositions.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: February 16, 2021
    Assignees: Vestlandets Innovasjonsseiskap AS, NEWSOUTH INNOVATIONS PTY LIMITED
    Inventors: Ralf Kellmann, Brett Neilan
  • RECOMBINANT MICROCYSTIN PRODUCTION
    Publication number: 20190263868
    Abstract: The present invention relates generally to methods for producing microcystin and recombinant cells capable of producing microcystin. The recombinant cells express exogenous microcystin synthase polypeptides under the control of an exogenous promoter, and further express an exogenous phosphopantethienyl transferase (PPTase). The present invention further relates to microcystin as produced in recombinant cells by the methods described herein.
    Type: Application
    Filed: October 17, 2017
    Publication date: August 29, 2019
    Inventors: Brett Neilan, Tianzhe Liu, Rabia Mazmouz, Sarah Ongley
  • PROCESS
    Publication number: 20190048375
    Abstract: The present invention relates to processes to make neosaxitoxin, and analogues and variants thereof, and intermediates in the production of neosaxitoxin in recombinant host cells. Neosaxitoxin and the analogues and variants thereof may be used in the production of pharmaceutical compositions.
    Type: Application
    Filed: February 10, 2017
    Publication date: February 14, 2019
    Applicants: Bergen Teknologioverføring AS, University of New South Wales Innovations, University of New South Wales Innovations
    Inventors: Ralf Kellmann, Brett Neilan
  • Detection of hepatotoxic cyanobacteria
    Publication number: 20090275018
    Abstract: The present invention relates to methods and kits for the detection of toxic cyanobacteria, in particular of hepatotoxin-producing cyanobacteria.
    Type: Application
    Filed: May 31, 2006
    Publication date: November 5, 2009
    Applicant: New South Innovations PTY Limited
    Inventor: Brett Neilan