Patents by Inventor Brett Runge

Brett Runge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240117138
    Abstract: Disclosed are polymeric foamed compositions, foam padded materials that include such polymeric foamed compositions disposed on a sheet material, and packaging articles (e.g., envelopes) made from such foam padded materials. The polymeric foamed composition on the sheet material has a plurality of foamed structures formed from the foamable composition attached to the sheet material by a layer of the foamable composition, and the plurality foam structures each having a hollow core and a foam exterior shell.
    Type: Application
    Filed: February 1, 2022
    Publication date: April 11, 2024
    Inventors: Yaohua Gao, Stephen M. Sanocki, Sithya S. Khieu, Ignatius A. Kadoma, Cory D. Sauer, Tien Yi T.H. Whiting, Mitchell A.F. Johnson, Jeffrey P. Kalish, Daniel L. Schlosser, Michael Brett Runge, Matt R. Branscomb
  • Publication number: 20200181318
    Abstract: A polycaprolactone fumarate copolymer useful as a material for a biocompatible scaffold for tissue engineering applications is disclosed. The copolymer includes at least one caprolactone unit, at least one fumarate unit, and at least one third unit selected from the group consisting of acrylate units and styrenic units. A linking moiety forms a link between the third unit and at least one caprolactone unit or at least one fumarate unit. The linking moiety can be photodegradable. In one form, the third unit includes at least one methyl methacrylate unit. The copolymer can be used to form the wall of a nerve conduit.
    Type: Application
    Filed: January 14, 2020
    Publication date: June 11, 2020
    Inventors: Michael Brett Runge, Michael J. Yaszemski
  • Publication number: 20200108171
    Abstract: A polycaprolactone fumarate polymer useful as a matrix material for a biocompatible scaffold for tissue engineering applications is disclosed. The polycaprolactone fumarate polymer can be prepared by reacting caprolactone with an alkane polyol to prepare a polycaprolactone precursor, and then reacting the polycaprolactone precursor with fumaric acid or a salt thereof to prepare the polycaprolactone fumarate polymer. The use of an alkane diol, such as 1,2-propanediol, provides a linear polycaprolactone diol precursor. The use of an alkane triol, such as glycerol, provides a branched polycaprolactone triol precursor. The biocompatible polycaprolactone fumarate formulation releases no diethylene glycol or other undesirable byproducts during degradation.
    Type: Application
    Filed: September 27, 2019
    Publication date: April 9, 2020
    Inventors: Michael Brett Runge, Michael J. Yaszemski
  • Patent number: 10568985
    Abstract: A polycaprolactone fumarate copolymer useful as a material for a biocompatible scaffold for tissue engineering applications is disclosed. The copolymer includes at least one caprolactone unit, at least one fumarate unit, and at least one third unit selected from the group consisting of acrylate units and styrenic units. A linking moiety forms a link between the third unit and at least one caprolactone unit or at least one fumarate unit. The linking moiety can be photodegradable. In one form, the third unit includes at least one methyl methacrylate unit. The copolymer can be used to form the wall of a nerve conduit.
    Type: Grant
    Filed: July 31, 2013
    Date of Patent: February 25, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Michael Brett Runge, Michael J. Yaszemski
  • Patent number: 10426867
    Abstract: A polycaprolactone fumarate polymer useful as a matrix material for a biocompatible scaffold for tissue engineering applications is disclosed. The polycaprolactone fumarate polymer can be prepared by reacting caprolactone with an alkane polyol to prepare a polycaprolactone precursor, and then reacting the polycaprolactone precursor with fumaric acid or a salt thereof to prepare the polycaprolactone fumarate polymer. The use of an alkane diol, such as 1,2-propanediol, provides a linear polycaprolactone diol precursor. The use of an alkane triol, such as glycerol, provides a branched polycaprolactone triol precursor. The biocompatible polycaprolactone fumarate formulation releases no diethylene glycol or other undesirable byproducts during degradation.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: October 1, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Michael Brett Runge, Michael J. Yaszemski
  • Patent number: 10157601
    Abstract: A strap button and connector for connecting one end of a strap to a musical instrument or other body consists of a connector fixed to the instrument and a removable strap button to hold a strap securely. The connector has a large opening or mouth and is designed so that the strap button and the connector be easily engaged or disengaged. When the threaded neck of strap button is received into threaded connector cavity the strap button is easily hand screwed together and the additional aid of a rubber washer placed between strap button neck and connector head or lip keeps the two parts from disengaging. The strap at this point is secure from coming off the strap button and the strap still has movability between player and instrument.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: December 18, 2018
    Inventor: Brett Runge
  • Publication number: 20140099278
    Abstract: A polycaprolactone fumarate polymer useful as a matrix material for a biocompatible scaffold for tissue engineering applications is disclosed. The polycaprolactone fumarate polymer can be prepared by reacting caprolactone with an alkane polyol to prepare a polycaprolactone precursor, and then reacting the polycaprolactone precursor with fumaric acid or a salt thereof to prepare the polycaprolactone fumarate polymer. The use of an alkane diol, such as 1,2-propanediol, provides a linear polycaprolactone diol precursor. The use of an alkane triol, such as glycerol, provides a branched polycaprolactone triol precursor. The biocompatible polycaprolactone fumarate formulation releases no diethylene glycol or other undesirable byproducts during degradation.
    Type: Application
    Filed: April 4, 2012
    Publication date: April 10, 2014
    Inventors: Michael Brett Runge, Michael J. Yaszemski
  • Publication number: 20140039075
    Abstract: A polycaprolactone fumarate copolymer useful as a material for a biocompatible scaffold for tissue engineering applications is disclosed. The copolymer includes at least one caprolactone unit, at least one fumarate unit, and at least one third unit selected from the group consisting of acrylate units and styrenic units. A linking moiety forms a link between the third unit and at least one caprolactone unit or at least one fumarate unit. The linking moiety can be photodegradable. In one form, the third unit includes at least one methyl methacrylate unit. The copolymer can be used to form the wall of a nerve conduit.
    Type: Application
    Filed: July 31, 2013
    Publication date: February 6, 2014
    Inventors: Michael Brett Runge, Michael J. Yaszemski
  • Publication number: 20130331869
    Abstract: A novel electrically conductive polymer composite composed of polycaprolactone fumarate-polypyrrole (PCLF-PPy) for applications in nerve regeneration is disclosed. The synthesis and characterization of PCLF-PPy and in vitro studies showing PCLF-PPy supports both PC12 cell and Dorsal Root Ganglia neurite extension. PCLF-PPy composite materials were synthesized by polymerizing pyrrole in pre-formed scaffolds of PCLF resulting in an interpenetrating network of PCLF-PPy. PCLF-PPy composite materials possess electrical conductivity up to 6 mS cm?1 with compositions ranging from 5-13.5 percent polypyrrole of the bulk material. Surface topographies of PCLF-PPy materials show microstructures with a RMS roughness of 1195 nm and nanostructures with RMS roughness of 8 nm. PCLF-PPy derivatives were synthesized with anionic dopants to determine effects on electrical conductivity and to optimize the chemical composition for biocompatibility.
    Type: Application
    Filed: October 15, 2010
    Publication date: December 12, 2013
    Inventors: M. Brett Runge, Mahrokh Dadsetan, Michael J. Yaszemski
  • Patent number: 8227635
    Abstract: The invention provides methods and an apparatus useful for site-isolating reagents or catalysts during chemical reactions. The methods and apparatus are useful for carrying out cascade or domino reactions.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: July 24, 2012
    Assignee: University of Iowa Research Foundation
    Inventors: Ned Bowden, Michael Brett Runge, Alan Lee Miller, III
  • Publication number: 20090299102
    Abstract: The invention provides methods and an apparatus useful for site-isolating reagents or catalysts during chemical reactions. The methods and apparatus are useful for carrying out cascade or domino reactions.
    Type: Application
    Filed: June 2, 2009
    Publication date: December 3, 2009
    Applicant: University of Iowa Research Foundation
    Inventors: Ned Bowden, Michael Brett Runge, Alan Lee Miller, III