Patents by Inventor Brett Turney

Brett Turney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chloral-free DCA in oligonucleotide synthesis
    Patent number: 7759480
    Abstract: A process of manufacturing oligonucleotides includes a 5?-deblocking step in which the 5-blocking group is removed with dichloroacetic acid that is essentially free of chloral. The process is useful for making oligonucleotides that are substantially free of chloral adducts.
    Type: Grant
    Filed: January 29, 2007
    Date of Patent: July 20, 2010
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Achim Krotz, Daniel C. Capaldi, Hans-Joachim Josef Gaus, Brett Turney
  • CHLORAL-FREE DCA IN OLIGONUCLEOTIDE SYNTHESIS
    Publication number: 20070123703
    Abstract: A process of manufacturing oligonucleotides includes a 5?-deblocking step in which the 5-blocking group is removed with dichloroacetic acid that is essentially free of chloral. The process is useful for making oligonucleotides that are substantially free of chloral adducts.
    Type: Application
    Filed: January 29, 2007
    Publication date: May 31, 2007
    Applicant: Isis Pharmaceuticals, Inc.
    Inventors: Achim Krotz, Daniel Capaldi, Hans Gaus, Brett Turney
  • Chloral-free DCA in oligonucleotide synthesis
    Patent number: 7169916
    Abstract: A process of manufacturing oligonucleotides includes a 5?-deblocking step in which the 5-blocking group is removed with dichloroacetic acid that is essentially free of chloral. The process is useful for making oligonucleotides that are substantially free of chloral adducts.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: January 30, 2007
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Achim Krotz, Daniel Capaldi, Hans Gaus, Brett Turney
  • Chloral-free DCA in oligonucleotide synthesis
    Publication number: 20050075490
    Abstract: A process of manufacturing oligonucleotides includes a 5?-deblocking step in which the 5-blocking group is removed with dichloroacetic acid that is essentially free of chloral. The process is useful for making oligonucleotides that are substantially free of chloral adducts.
    Type: Application
    Filed: March 31, 2003
    Publication date: April 7, 2005
    Inventors: Achim Krotz, Daniel Capaldi, Hans Gaus, Brett Turney