Abstract: A laminar material suitable for use in the manufacture of shoes comprising an extruded core (10) having laminated thereto on both sides a fiber fabric layer (12), the thermoplastic sheet core (10) comprising a mixture of granulated scrap shoe stiffener material with virgin extrudable thermoplastics material the core including at least 40% by weight of virgin extrudable thermoplastics material. Hot melt adhesive coatings (14) are applied on both sides. The scrap material in the core (10) includes fibrous particles (16). A method of making such a material is also described.

Abstract: The present invention provides novel sulphonamide derivatives which are useful for potentiating glutamate receptor function in a mammal requiring treatment, processes for their preparation, and pharmaceutical compositions containing them.

Abstract: The present invention provides compounds of formula ##STR1## in which R represents an organic group, or a pharmaceutically acceptable metabolically labile ester or amide thereof, or a pharmaceutically acceptable salt thereof, which are useful as antagonists of one or more of the actions of L-glutamate at metabotropic excitatory amino acid receptors.

Abstract: This invention provides novel decahydroisoquinoline compounds which are useful as excitatory amino acid receptor antagonists and in the treatment of neurological disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as, novel intermediates in the synthesis thereof.

Abstract: This invention provides novel decahydroisoquinoline compounds which are useful as excitatory amino acid receptor antagonists and in the treatment of neurological disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as, novel intermediates in the synthesis thereof.

Abstract: This invention provides novel decahydroisoquinoline compounds which are useful as excitatory amino acid receptor antagonists and in the treatment of neurological disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as, novel intermediates in the synthesis thereof.

Abstract: A reinforcing material comprises an E-polycaprolactone binder in admixture with a filler. Said filler is pulverized fuel ash, and said mixture comprises from 50 to 95% by weight of polycaprolactone, from 5 to 45% by weight of pulverized fuel ash and from 0 to 20% by weight of other fillers and/or diluents.The reinforcing material is particularly suitable for the reinforcing and stiffening of materials for use in the manufacture of shoes.

Abstract: The invention presents to the art a novel, improved shoe stiffener which comprises co-extruded layers of plastics film. The shoe stiffener comprises co-extruded layers of plastics film, a first of the layers comprising an ionomeric material and providing a main body of the stiffener and a second layer comprising a plastics material which does not adhere to a fusion press under conditions normally encountered therein during bonding of a shoe stiffener to a shoe upper. Nylon 6 is the preferred second layer plastics material. The co-extrusion product replaces fabric backed shoe stiffeners in which flaws induced in the film by the fabric may provide notches from which cracks in the material can propagate.

Abstract: Shoe insoles comprise two layers of non-woven fibre fleece adhered to an impermeable plastics film. In preferred constructions at least one layer of woven reinforcing fabric is included and more than one plastics film layer may also be included in the insoles.

Abstract: An endoprosthetic shoulder joint device has a scapular component of generally L-shape, usually with one arm longer than the other, and formed with a spherical concave bearing surface in its inner face to extend at least over the free end portion of the longer arm. If the concave surface extends in the shorter arm, the latter arm is thickened for this purpose. The concave surface can open into the edges of the L-shape, the longer arm is usually of cranked form, and the outer face is relieved for cement securement keying. The associated humeral component can be of conventional ball-headed, stemmed form, but is preferred as a spherical segmental form which is solid with a short stem projecting from its chordal face, or hollowed and grooved in its interior.