Patents by Inventor Brian A. Carr

Brian A. Carr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies that target HIV gp120 and methods of use
    Patent number: 12338278
    Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
    Type: Grant
    Filed: October 7, 2021
    Date of Patent: June 24, 2025
    Assignee: Gilead Sciences, Inc.
    Inventors: Mini Balakrishnan, Brian A. Carr, Magdeleine S. Hung, Manu Kanwar, Craig S. Pace, Doug Rehder, Matthew R. Schenauer, Loredana Serafini, Heather T. Stephenson, Nathan D. Thomsen, Helen Yu, Xue Zhang
  • MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE
    Publication number: 20250059261
    Abstract: Provided are multi-specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein gp120. Also provided are methods of using such antigen binding molecules to treat or prevent HIV infection.
    Type: Application
    Filed: July 12, 2024
    Publication date: February 20, 2025
    Inventors: Manuel Baca, Wade S. Blair, Brian A. Carr, Sheila B. Clancy, Joshua Goldsmith, Magdeleine S. Hung, Manu Kanwar, Brian Moldt, Mark Nagel, Craig S. Pace, YenRu Pan, Heather T. Stephenson, Nathan D. Thomsen
  • Multi-specific antigen binding molecules targeting HIV and methods of use
    Patent number: 12195524
    Abstract: Provided are multi-specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein gp120. Also provided are methods of using such antigen binding molecules to treat or prevent HIV infection.
    Type: Grant
    Filed: August 23, 2021
    Date of Patent: January 14, 2025
    Assignee: Gilead Sciences, Inc.
    Inventors: Manuel Baca, Brian A. Carr, Sheila B. Clancy, Craig S. Pace, Heather T. Stephenson, Nathan D. Thomsen
  • Antibodies that target HIV GP120 and methods of use
    Patent number: 11987617
    Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
    Type: Grant
    Filed: August 4, 2023
    Date of Patent: May 21, 2024
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Mini Balakrishnan, Brian A. Carr, Magdeleine S. Hung, Manu Kanwar, Doug Rehder, Matthew Robert Schenauer, Loredana Serafini, Nathan D. Thomsen
  • ANTIBODIES THAT TARGET HIV GP120 AND METHODS OF USE
    Publication number: 20240034774
    Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
    Type: Application
    Filed: August 4, 2023
    Publication date: February 1, 2024
    Inventors: Mini Balakrishnan, Brian A. Carr, Magdeleine S. Hung, Manu Kanwar, Craig S. Pace, Doug Rehder, Matthew Robert Schenauer, Loredana Serafini, Heather Theresa Stephenson, Nathan D. Thomsen, Helen Yu, Xue Zhang
  • Human immunodeficiency virus neutralizing antibodies
    Patent number: 11655285
    Abstract: The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
    Type: Grant
    Filed: December 3, 2020
    Date of Patent: May 23, 2023
    Assignee: Gilead Sciences, Inc.
    Inventors: Mini Balakrishnan, Brian A. Carr, John Corbin, Craig S. Pace, Nathan D. Thomsen, Xue Zhang
  • MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE
    Publication number: 20230056252
    Abstract: Provided are multi-specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein gp120. Also provided are methods of using such antigen binding molecules to treat or prevent HIV infection.
    Type: Application
    Filed: August 23, 2021
    Publication date: February 23, 2023
    Inventors: Manuel Baca, Wade S. Blair, Brian A. Carr, Sheila B. Clancy, Joshua Goldsmith, Magdeleine S. Hung, Manu Kanwar, Brian Moldt, Mark Nagel, Craig S. Pace, YenRu Pan, Heather T. Stephenson, Nathan D. Thomsen
  • ANTIBODIES THAT TARGET HIV GP120 AND METHODS OF USE
    Publication number: 20220089698
    Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
    Type: Application
    Filed: October 7, 2021
    Publication date: March 24, 2022
    Inventors: Mini Balakrishnan, Brian A. Carr, Magdeleine S. Hung, Manu Kanwar, Craig S. Pace, Doug Rehder, Matthew Robert Schenauer, Loredana Serafini, Heather Theresa Stephenson, Nathan D. Thomsen, Helen Yu, Xue Zhang
  • FLT3L-Fc FUSION PROTEINS AND METHODS OF USE
    Publication number: 20220049021
    Abstract: Provided are FLT3L-Fc fusion proteins, polynucleotides encoding such fusion proteins, expression cassettes, vectors, cells and kits comprising such fusion proteins, and methods of using.
    Type: Application
    Filed: August 18, 2021
    Publication date: February 17, 2022
    Inventors: Alexandre Ambrogelly, Manuel Baca, Brian A. Carr, Hon Man Hamlet Chu, Magdeleine S. Hung, Manu Kanwar, Michelle R. Kuhne, Douglas S. Rehder, Matthew R. Schenauer, Nicholas S. Wilson
  • Antibodies that target HIV GP120 and methods of use
    Patent number: 11168130
    Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: November 9, 2021
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Mini Balakrishnan, Brian A. Carr, Craig S. Pace, Doug Rehder, Matthew Robert Schenauer, Loredana Serafini, Heather Theresa Stephenson, Nathan D. Thomsen, Helen Yu, Xue Zhang
  • FLT3L-FC fusion proteins
    Patent number: 11124582
    Abstract: Provided are FLT3L-Fc fusion proteins, polynucleotides encoding such fusion proteins, expression cassettes, vectors, cells and kits comprising such fusion proteins, and methods of using.
    Type: Grant
    Filed: November 18, 2020
    Date of Patent: September 21, 2021
    Assignee: Gilead Sciences, Inc.
    Inventors: Alexandre Ambrogelly, Manuel Baca, Brian A. Carr, Hon Man Hamlet Chu, Magdeleine S. Hung, Manu Kanwar, Michelle R. Kuhne, Douglas S. Rehder, Matthew R. Schenauer, Nicholas S. Wilson
  • HUMAN IMMUNODEFICIENCY VIRUS NEUTRALIZING ANTIBODIES
    Publication number: 20210155676
    Abstract: The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
    Type: Application
    Filed: December 3, 2020
    Publication date: May 27, 2021
    Inventors: Mini Balakrishnan, Brian A. Carr, John Corbin, Craig S. Pace, Nathan D. Thomsen, Xue Zhang
  • FLT3L-Fc FUSION PROTEINS AND METHODS OF USE
    Publication number: 20210070887
    Abstract: Provided are FLT3L-Fc fusion proteins, polynucleotides encoding such fusion proteins, expression cassettes, vectors, cells and kits comprising such fusion proteins, and methods of using.
    Type: Application
    Filed: November 18, 2020
    Publication date: March 11, 2021
    Inventors: Alexandre Ambrogelly, Manuel Baca, Brian A. Carr, Hon Man Hamlet Chu, Magdeleine S. Hung, Manu Kanwar, Michelle R. Kuhne, Douglas S. Rehder, Matthew R. Schenauer, Nicholas S. Wilson
  • FLT3L-Fc FUSION PROTEINS AND METHODS OF USE
    Publication number: 20210009718
    Abstract: Provided are FLT3L-Fc fusion proteins, polynucleotides encoding such fusion proteins, expression cassettes, vectors, cells and kits comprising such fusion proteins, and methods of using.
    Type: Application
    Filed: June 23, 2020
    Publication date: January 14, 2021
    Inventors: Alexandre Ambrogelly, Manuel Baca, Brian A. Carr, Hon Man Hamlet Chu, Magdeleine S. Hung, Manu Kanwar, Michelle R. Kuhne, Douglas S. Rehder, Matthew R. Schenauer, Nicholas S. Wilson
  • Human immunodeficiency virus neutralizing antibodies
    Patent number: 10882898
    Abstract: The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: January 5, 2021
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Mini Balakrishnan, Brian A. Carr, John Corbin, Craig S. Pace, Nathan D. Thomsen, Xue Zhang
  • ANTIBODIES THAT TARGET HIV GP120 AND METHODS OF USE
    Publication number: 20200223907
    Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
    Type: Application
    Filed: July 2, 2019
    Publication date: July 16, 2020
    Applicant: Gilead Sciences, Inc.
    Inventors: Mini Balakrishnan, Brian A. Carr, Magdeleine S. Hung, Manu Kanwar, Craig S. Pace, Doug Rehder, Matthew Robert Schenauer, Loredana Serafini, Heather Theresa Stephenson, Nathan D. Thomsen, Helen Yu, Xue Zhang
  • HUMAN IMMUNODEFICIENCY VIRUS NEUTRALIZING ANTIBODIES
    Publication number: 20190211083
    Abstract: The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
    Type: Application
    Filed: February 12, 2019
    Publication date: July 11, 2019
    Applicant: Gilead Sciences, Inc.
    Inventors: Mini Balakrishnan, Brian A. Carr, John Corbin, Craig S. Pace, Nathan D. Thomsen, Xue Zhang
  • Human immunodeficiency virus neutralizing antibodies
    Patent number: 10239935
    Abstract: The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: March 26, 2019
    Assignee: Gilead Sciences, Inc.
    Inventors: Mini Balakrishnan, Brian A. Carr, John Corbin, Craig S. Pace, Nathan D. Thomsen, Xue Zhang
  • HUMAN IMMUNODEFICIENCY VIRUS NEUTRALIZING ANTIBODIES
    Publication number: 20170190763
    Abstract: The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
    Type: Application
    Filed: December 14, 2016
    Publication date: July 6, 2017
    Inventors: Mini Balakrishnan, Brian A. Carr, John Corbin, Craig S. Pace, Nathan D. Thomson, Xue Zhang
  • Monolithic backplane having a first and second portion
    Patent number: 7388757
    Abstract: A subrack having a front side and a rear side, wherein the subrack is coupled to receive an Advanced Mezzanine Card module, the subrack includes a monolithic backplane having a first portion and second portion, where the first portion runs substantially along the front side and the second portion runs substantially along the rear side. A first slot is to receive the Advanced Mezzanine Card module inserted via the front side and connect the Advanced Mezzanine Card module directly to the second portion of the monolithic backplane. A second slot is to receive the Advanced Mezzanine Card module inserted via the rear side and connect the Advanced Mezzanine Card module directly to the first portion of the monolithic backplane.
    Type: Grant
    Filed: November 28, 2005
    Date of Patent: June 17, 2008
    Assignee: Emerson Network Power - Embedded Computing, Inc.
    Inventors: Paul A. Moakes, Brian A. Carr