Patents by Inventor Brian A. Dougherty

Brian A. Dougherty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • polypeptides
    Patent number: 8168205
    Abstract: The present invention provides polynucleotide sequences of the genome of Streptococcus pneumoniae, polypeptide sequences encoded by the polynucleotide sequences, corresponding polynucleotides and polypeptides, vectors and hosts comprising the polynucleotides, and assays and other uses thereof. The present invention further provides polynucleotide and polypeptide sequence information stored on computer readable media, and computer-based systems and methods which facilitate its use.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: May 1, 2012
    Assignee: Human Genome Sciences, Inc.
    Inventors: Charles A. Kunsch, Gil H. Choi, Patrick J. Dillon, Craig A. Rosen, Steven C. Barash, Michael R. Fannon, Brian A. Dougherty
  • Essential fungal polypeptide, CaYDR341c, and methods of use thereof
    Patent number: 7790428
    Abstract: The present invention provides essential fungal polynucleotides and their encoded polypeptides, homologues thereof and their uses. Additionally, the invention provides methods for the identification of essential polynucleotides and fungal strains which may be used for drug screening.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: September 7, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ying-Kai Wang, Mengping Liu, Brian A. Dougherty, Matthew D. Healy, Daniel B. Davison, Charles E. Mazzucco, Trina Maurice
  • Streptococcus pneumoniae Polynucleotides and Sequences
    Publication number: 20100221287
    Abstract: The present invention provides polynucleotide sequences of the genome of Streptococcus pneumoniae, polypeptide sequences encoded by the polynucleotide sequences, corresponding polynucleotides and polypeptides, vectors and hosts comprising the polynucleotides, and assays and other uses thereof. The present invention further provides polynucleotide and polypeptide sequence information stored on computer readable media, and computer-based systems and methods which facilitate its use.
    Type: Application
    Filed: December 11, 2009
    Publication date: September 2, 2010
    Applicant: Human Genome Sciences, Inc.
    Inventors: Charles A. Kunsch, Gil H. Choi, Patrick J. Dillon, Craig A. Rosen, Steven C. Barash, Michael R. Fannon, Brian A. Dougherty
  • Essential fungal polynucleotides, polypeptides, and methods of use
    Patent number: 7465568
    Abstract: The presnt invention provides essential fungal polynucleotides and their encoded polypeptides, homologues thereof and their uses. Additionally, the invention provides methods for the identification of essential polynucleotides and fungal strains which may be used for drug screening.
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: December 16, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ying-Kai Wang, Mengping Liu, Brian A. Dougherty, Matthew D. Healy, Daniel B. Davison, Charles E. Mazzucco, Trina C. Maurice
  • Essential fungal CaYLR100w polypeptides, and methods of use
    Patent number: 7442532
    Abstract: The present invention provides essential fungal polynucleotides and their encoded polypeptides, homologues thereof and their uses. Additionally, the invention provides methods for the identification of essential polynucleotides and fungal strains which may be used for drug screening.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: October 28, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ying-Kai Wang, Mengping Liu, Brian A. Dougherty, Matthew D. Healy, Daniel B. Davison, Charles E. Mazzucco, Trina Maurice
  • Compositions and methods for altering biosynthesis of taxanes and taxane-related compounds
    Patent number: 7273755
    Abstract: Isolated nucleic acid and amino acid sequences for phenylalanine aminomutase enzyme and methods for purifying this enzyme are provided. Methods for altering biosynthesis of compounds in plant cell cultures are also provided. In particular, methods for altering production of taxanes and taxane-related compounds are provided.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: September 25, 2007
    Assignee: Bristol Myers Squibb Co.
    Inventors: Christopher L. Steele, Yijun Chen, Brian A. Dougherty, Sandra Hofstead, Kin S. Lam, Wenying Li, Zizhuo Xing
  • polynucleotides and sequences
    Patent number: 7141418
    Abstract: The present invention provides polynucleotide sequences of the genome of Streptococcus pneumoniae, polypeptide sequences encoded by the polynucleotide sequences, corresponding polynucleotides and polypeptides, vectors and hosts comprising the polynucleotides, and assays and other uses thereof. The present invention further provides polynucleotide and polypeptide sequence information stored on computer readable media, and computer-based systems and methods which facilitate its use.
    Type: Grant
    Filed: June 3, 2002
    Date of Patent: November 28, 2006
    Assignee: Human Genome Sciences, Inc.
    Inventors: Charles A. Kunsch, Gil H. Choi, Patrick J. Dillon, Craig A. Rosen, Steven C. Barash, Michael R. Fannon, Brian A. Dougherty
  • Streptococcus pneumoniae polynucleotides and sequences
    Publication number: 20040029118
    Abstract: The present invention provides polynucleotide sequences of the genome of Streptococcus pneumoniae, polypeptide sequences encoded by the polynucleotide sequences, corresponding polynucleotides and polypeptides, vectors and hosts comprising the polynucleotides, and assays and other uses thereof. The present invention further provides polynucleotide and polypeptide sequence information stored on computer readable media, and computer-based systems and methods which facilitate its use.
    Type: Application
    Filed: June 3, 2002
    Publication date: February 12, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Charles A. Kunsch, Gil H. Choi, Patrick J. Dillon, Craig A. Rosen, Steven C. Barash, Michael R. Fannon, Brian A. Dougherty
  • Compositions and methods for altering biosynthesis of taxanes and taxane-related compounds
    Publication number: 20030175913
    Abstract: Isolated nucleic acid and amino acid sequences for phenylalanine aminomutase enzyme and methods for purifying this enzyme are provided. Methods for altering biosynthesis of compounds in plant cell cultures are also provided. In particular, methods for altering production of taxanes and taxane-related compounds are provided.
    Type: Application
    Filed: February 10, 2003
    Publication date: September 18, 2003
    Inventors: Christopher L. Steele, Yijun Chen, Brian A. Dougherty, Sandra Hofstead, Kin S. Lam, Wenying Li, Zizhuo Xing
  • Streptococcus pneumoniae polynucleotides and sequences
    Patent number: 6420135
    Abstract: The present invention provides polynucleotide sequences of the genome of Streptococcus pneumoniae, polypeptide sequences encoded by the polynucleotide sequences, corresponding polynucleotides and polypeptides, vectors and hosts comprising the polynucleotides, and assays and other uses thereof. The present invention further provides polynucleotide and polypeptide sequence information stored on computer readable media, and computer-based systems and methods which facilitate its use.
    Type: Grant
    Filed: October 30, 1997
    Date of Patent: July 16, 2002
    Assignee: Human Genome Sciences, Inc.
    Inventors: Charles A. Kunsch, Gil H. Choi, Patrick S. Dillon, Craig A. Rosen, Steven C. Barash, Michael R. Fannon, Brian A. Dougherty