Patents by Inventor Brian A. Dukek

Brian A. Dukek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210130911
    Abstract: Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
    Type: Application
    Filed: January 8, 2021
    Publication date: May 6, 2021
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi
  • Patent number: 10934592
    Abstract: Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: March 2, 2021
    Assignees: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, EXACT SCIENCES DEVELOPMENT COMPANY, LLC
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi
  • Publication number: 20200291453
    Abstract: The invention provides compositions and methods for accurately and specifically amplifying sequences to allow for accurate and specific detection of mutations, such as in disease-associated genes and alleles, thus distinguishing true nucleotide variants over random nucleotide sequencing errors. In one embodiment, this is accomplished, prior to sequencing, by using a combination of director and driver in a combination of two PCR reactions. Thus, in one embodiment, this is accomplished by amplifying a nucleotide sequence of interest to introduce a director that creates a specific target for a subsequent amplification in which a driver that specifically hybridizes to the director drives the specificity of further amplification. The amplification produces an amplicon of a sense or antisense strand of a double-stranded nucleotide sequence of interest.
    Type: Application
    Filed: January 15, 2020
    Publication date: September 17, 2020
    Inventors: Brian A. Dukek, Manish J. Gandhi
  • Publication number: 20180245163
    Abstract: Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
    Type: Application
    Filed: February 27, 2018
    Publication date: August 30, 2018
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi