Patents by Inventor Brian A. Leuthner

Brian A. Leuthner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTRAVENTRICULAR DRUG DELIVERY SYSTEM FOR IMPROVING OUTCOME AFTER A BRAIN INJURY AFFECTING CEREBRAL BLOOD FLOW
    Publication number: 20160193198
    Abstract: The described invention provides a flowable sustained release microparticulate composition effective to improve cerebral perfusion and to treat a delayed complication of a brain injury mediated by decreased cerebral perfusion that deposits blood in a subarachnoid space of the brain. The described invention also provides a method for preparing a flowable sustained release microparticulate composition.
    Type: Application
    Filed: March 14, 2016
    Publication date: July 7, 2016
    Inventors: R. Loch Macdonald, Brian A. Leuthner
  • Intraventricular drug delivery system for improving outcome after a brain injury affecting cerebral blood flow
    Patent number: 9364432
    Abstract: The described invention provides a flowable sustained release microparticulate composition, a kit for treating at least one cerebral artery in a subarachnoid space at risk of interruption due to a brain injury, a method of preparing the composition, and a method for treating an interruption of a cerebral artery in a subarachnoid space at risk of interruption caused by brain injury in a mammal, which reduces signs or symptoms of at least one delayed complication associated with brain injury.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: June 14, 2016
    Assignee: Edge Therapeutics, Inc.
    Inventors: R. Loch Macdonald, Brian A. Leuthner
  • DRUG DELIVERY SYSTEM FOR THE PREVENTION OF CEREBRAL VASOSPASM
    Publication number: 20130022660
    Abstract: The present invention relates to the treatment and prevention of vasospasm. The present invention provides a system for treating a cerebral vasospasm in a human utilizing a pharmaceutical composition and administrating a therapeutically effective amount of the pharmaceutical composition to a predetermined location in close proximity to a cerebral artery within a subarachnoid space wherein the pharmaceutical composition produces a localized pharmacologic effect thereby treating the cerebral vasospasm.
    Type: Application
    Filed: July 22, 2012
    Publication date: January 24, 2013
    Applicant: EDGE THERAPEUTICS, INC.
    Inventors: R. Loch Macdonald, Brian A. Leuthner
  • Drug delivery system for the prevention of cerebral vasospasm
    Patent number: 8303974
    Abstract: The present invention relates to the treatment and prevention of vasospasm. The present invention provides a system for treating a cerebral vasospasm in a human utilizing a pharmaceutical composition and administrating a therapeutically effective amount of the pharmaceutical composition to a predetermined location in close proximity to a cerebral artery within a subarachnoid space wherein the pharmaceutical composition produces a localized pharmacologic effect thereby treating the cerebral vasospasm.
    Type: Grant
    Filed: June 11, 2008
    Date of Patent: November 6, 2012
    Assignee: Edge Therapeutics, Inc.
    Inventors: R. Loch Macdonald, Brian Leuthner
  • INTRAVENTRICULAR DRUG DELIVERY SYSTEM FOR IMPROVING OUTCOME AFTER A BRAIN INJURY AFFECTING CEREBRAL BLOOD FLOW
    Publication number: 20120245561
    Abstract: The described invention provides a flowable sustained release microparticulate composition, a kit for treating at least one cerebral artery in a subarachnoid space at risk of interruption due to a brain injury, a method of preparing the composition, and a method for treating an interruption of a cerebral artery in a subarachnoid space at risk of interruption caused by brain injury in a mammal, which reduces signs or symptoms of at least one delayed complication associated with brain injury.
    Type: Application
    Filed: April 5, 2012
    Publication date: September 27, 2012
    Inventors: R. Loch Macdonald, Brian A. Leuthner
  • Compositions and Methods for Improving Prognosis of a Human with Subarachnoid Hemorrhage
    Publication number: 20120164226
    Abstract: The described invention provides a pharmaceutical composition, delivery system and a method for treating a delayed complication associated with a brain injury in a mammal and improving its prognosis in a mammal by implanting a therapeutically effective amount of the pharmaceutical composition containing a voltage-gated calcium channel blocker and a pharmaceutically acceptable carrier into a predetermined location in the brain, which reduces signs or symptoms of at least one delayed complication associated with brain injury.
    Type: Application
    Filed: February 13, 2012
    Publication date: June 28, 2012
    Inventors: Brian A. Leuthner, R. Loch Macdonald
  • Drug Delivery System For The Prevention Of Cerebral Vasospasm
    Publication number: 20080305147
    Abstract: The present invention relates to the treatment and prevention of vasospasm. The present invention provides a system for treating a cerebral vasospasm in a human utilizing a pharmaceutical composition and administrating a therapeutically effective amount of the pharmaceutical composition to a predetermined location in close proximity to a cerebral artery within a subarachnoid space wherein the pharmaceutical composition produces a localized pharmacologic effect thereby treating the cerebral vasospasm.
    Type: Application
    Filed: June 11, 2008
    Publication date: December 11, 2008
    Inventors: R. Loch Macdonald, Brian Leuthner