Patents by Inventor Brian A. Marples

Brian A. Marples has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8539948
    Abstract: A breathing system for hyperthermic assisted radiation therapy includes at least one heating element that modulates the temperature of air inhaled by a patient, at least one cooling element that modulates the humidity of the air inhaled by a patient, and a controller that maintains the desired humidity and temperature.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: September 24, 2013
    Assignee: William Beaumont Hospital
    Inventors: Dan Ionascu, Brian Marples, Di Yan, Alvaro Martinez
  • Publication number: 20100294279
    Abstract: A breathing system for hyperthermic assisted radiation therapy includes at least one heating element that modulates the temperature of air inhaled by a patient, at least one cooling element that modulates the humidity of the air inhaled by a patient, and a controller that maintains the desired humidity and temperature.
    Type: Application
    Filed: May 18, 2010
    Publication date: November 25, 2010
    Applicant: William Beaumont Hospital
    Inventors: Dan Ionascu, Brian Marples, Di Yan, Alvaro Martinez
  • Patent number: 5304551
    Abstract: Compounds of the general formula (7): ##STR1## wherein X is a hydrogen atom or a hydroxyl group, Y is a hydrogen atom or a hydroxyl group and at least one of X and Y is a hydroxyl group and Z is a hydroxyl group or a methylol (--CH.sub.2 OH) group, have anti-fungal activity, especially against organisms selected from Candida spp. and the athlete's foot/ringworm organisms Trichophyton mentagrophytes and Microsporum audonii. Compounds in which Z is a methylol (--CH.sub.2 OH) group are claimed per se.
    Type: Grant
    Filed: October 27, 1992
    Date of Patent: April 19, 1994
    Assignee: British Technology Group Limited
    Inventors: Brian A. Marples, Reginald J. Stretton
  • Patent number: 5266566
    Abstract: Compounds of the general formula (2): ##STR1## wherein X is a hydrogen atom or a hydroxyl group, Y is a hydrogen atom or a hydroxyl group and R is an alkyl group of 1 to 4 carbon atoms, have anti-fungal activity, especially against organisms selected from Candida spp. and the athlete's foot organism Trichophyton mentagrophytes and the ringworm organism Microsporum audonii. Further, the compounds wherein X and R are hydrogen atoms and Y is a hydroxyl group (or its non-toxic salts) are useful against Microsporum audonii.
    Type: Grant
    Filed: November 4, 1991
    Date of Patent: November 30, 1993
    Assignee: British Technology Group Limited
    Inventors: Brian A. Marples, Reginald J. Stretton
  • Patent number: 4681876
    Abstract: A valuable alternative antifungal antibiotic, for treatment especially of candidiasis, particularly vaginal candidiasis, is proposed. The antibiotic is a bile acid or simple derivative (salt or conjugate) thereof. Cholic, deoxycholic, chenodeoxycholic and lithocholic acid are preferred bile acids. The antibiotic is formulated for topical application. It can be used in association with an anti-inflammatory steroid for the treatment of fungal infections of the skin. It is also proposed to inhibit fungal growth in a variety of pharmaceutical compositions (containing some other active ingredient) by including in the composition, or coating a tablet, pill or capsule with, the bile acid component.
    Type: Grant
    Filed: July 15, 1985
    Date of Patent: July 21, 1987
    Assignee: National Research Development Corporation
    Inventors: Brian A. Marples, Reginald J. Stretton