Patents by Inventor Brian A. MELTZER

Brian A. MELTZER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250322925
    Abstract: Described herein are methods of managing eosinophilic esophagitis (EoE) in a patient, wherein the patient records the number of episodes of dysphagia on a patient report outcome (PRO) questionnaire prior to and during the course of treatment. While on treatment, the number of episodes of dysphagia are reduced, as reported on the PRO questionnaire. In some embodiments, the esophageal eosinophils are counted before or after treatment, or both. In some embodiments, esophageal eosinophils counts are not correlated with a reduction in the episodes of dysphagia.
    Type: Application
    Filed: December 3, 2024
    Publication date: October 16, 2025
    Inventor: Brian A. MELTZER
  • Publication number: 20250170057
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Application
    Filed: June 26, 2024
    Publication date: May 29, 2025
    Inventors: Brian A. MELTZER, Gail M. COMER
  • Patent number: 12059494
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Grant
    Filed: September 11, 2023
    Date of Patent: August 13, 2024
    Assignee: ELLODI PHARMACEUTICALS, L.P.
    Inventors: Brian A. Meltzer, Gail M. Comer, Gina Eagle
  • Patent number: 11896710
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: February 13, 2024
    Assignee: Ellodi Pharmaceuticals, L.P.
    Inventors: Brian A. Meltzer, Gail M. Comer
  • Publication number: 20230414498
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Application
    Filed: September 11, 2023
    Publication date: December 28, 2023
    Inventors: Brian A. MELTZER, Gail M. COMER
  • Patent number: 11684571
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: June 27, 2023
    Assignee: Ellodi Pharmaceuticals, L.P.
    Inventors: Brian A. Meltzer, Gail M. Comer
  • Publication number: 20210346278
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Application
    Filed: July 15, 2021
    Publication date: November 11, 2021
    Inventors: Brian A. MELTZER, Gail M. COMER
  • Publication number: 20210275438
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Application
    Filed: May 3, 2021
    Publication date: September 9, 2021
    Inventors: Brian A. MELTZER, Gail M. COMER
  • Patent number: 11026887
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: June 8, 2021
    Assignee: ELLODI PHARMACEUTICALS, L.P.
    Inventors: Brian A. Meltzer, Gail M. Comer
  • Publication number: 20200381097
    Abstract: Described herein are methods of managing eosinophilic esophagitis (EoE) in a patient, wherein the patient records the number of episodes of dysphagia on a patient report outcome (PRO) questionnaire prior to and during the course of treatment. While on treatment, the number of episodes of dysphagia are reduced, as reported on the PRO questionnaire. In some embodiments, the esophageal eosinophils are counted before or after treatment, or both. In some embodiments, esophageal eosinophils counts are not correlated with a reduction in the episodes of dysphagia.
    Type: Application
    Filed: February 21, 2019
    Publication date: December 3, 2020
    Inventor: Brian A. MELTZER
  • Publication number: 20200368147
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Application
    Filed: August 13, 2020
    Publication date: November 26, 2020
    Inventors: Brian A. MELTZER, Gail M. COMER
  • Publication number: 20190008760
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Application
    Filed: September 14, 2018
    Publication date: January 10, 2019
    Inventors: Brian A. MELTZER, Gail M. COMER
  • Patent number: 10105315
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: October 23, 2018
    Assignee: Adare Pharmaceuticals, Inc.
    Inventors: Brian A. Meltzer, Gail M. Comer
  • Publication number: 20180133145
    Abstract: The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.
    Type: Application
    Filed: August 18, 2017
    Publication date: May 17, 2018
    Inventors: Brian A. MELTZER, Gail M. Comer