Patents by Inventor Brian A. RABINOVICH

Brian A. RABINOVICH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250002579
    Abstract: Provided are methods of generating chimeric antigen receptors (CAR). In some embodiments, library screening of CAR is performed by generating a vector encoding the CAR from random attachment of vectors from libraries of vectors encoding antigen-binding domains (e.g., scFv regions), hinge regions, and endodomains. In some embodiments, the vectors contain a transposon.
    Type: Application
    Filed: July 5, 2024
    Publication date: January 2, 2025
    Inventors: Laurence J.N. COOPER, Ana Beatriz KORNGOLD, Brian A. RABINOVICH, Harjeet SINGH, Simon OLIVARES
  • Patent number: 12065490
    Abstract: Provided are methods of generating chimeric antigen receptors (CAR). In some embodiments, library screening of CAR is performed by generating a vector encoding the CAR from random attachment of vectors from libraries of vectors encoding antigen-binding domains (e.g., scFv regions), hinge regions, and endodomains. In some embodiments, the vectors contain a transposon.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: August 20, 2024
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Laurence J. N. Cooper, Ana Beatriz Korngold, Brian A. Rabinovich, Harjeet Singh, Simon Olivares
  • Publication number: 20210324071
    Abstract: Provided are methods of generating chimeric antigen receptors (CAR). In some embodiments, library screening of CAR is performed by generating a vector encoding the CAR from random attachment of vectors from libraries of vectors encoding antigen-binding domains (e.g., scFv regions), hinge regions, and endodomains. In some embodiments, the vectors contain a transposon.
    Type: Application
    Filed: February 26, 2021
    Publication date: October 21, 2021
    Inventors: Laurence J.N. COOPER, Ana Beatriz KORNGOLD, Brian A. RABINOVICH, Harjeet SINGH, Simon OLIVARES
  • Publication number: 20190085079
    Abstract: Provided are methods of generating chimeric antigen receptors (CAR). In some embodiments, library screening of CAR is performed by generating a vector encoding the CAR from random attachment of vectors from libraries of vectors encoding antigen-binding domains (e.g., scFv regions), hinge regions, and endodomains. In some embodiments, the vectors contain a transposon.
    Type: Application
    Filed: September 28, 2018
    Publication date: March 21, 2019
    Inventors: Laurence J.N. Cooper, Ana Beatriz Korngold, Brian A. Rabinovich, Harjeet Singh, Simon Olivares
  • Patent number: 10125193
    Abstract: Provided are methods of generating chimeric antigen receptors (CAR). In some embodiments, library screening of CAR is performed by generating a vector encoding the CAR from random attachment of vectors from libraries of vectors encoding antigen-binding domains (e.g., scFv regions), hinge regions, and endodomains. In some embodiments, the vectors contain a transposon.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: November 13, 2018
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Laurence J. N. Cooper, Ana Beatriz Korngold, Brian A. Rabinovich, Harjeet Singh, Simon Olivares
  • Publication number: 20170183407
    Abstract: Provided are methods of generating chimeric antigen receptors (CAR). In some embodiments, library screening of CAR is performed by generating a vector encoding the CAR from random attachment of vectors from libraries of vectors encoding antigen-binding domains (e.g., scFv regions), hinge regions, and endodomains. In some embodiments, the vectors contain a transposon.
    Type: Application
    Filed: February 16, 2015
    Publication date: June 29, 2017
    Inventors: Laurence J.N. COOPER, Ana Beatriz KORNGOLD, Brian A. RABINOVICH, Harjeet SINGH, Simon OLIVARES