Abstract: Executing a query in a disaggregated cluster. A query is received at the disaggregated cluster. A query graph is created based on the query that identifies a hierarchy of vertices, where each vertex is associated with a set of data responsive to at least a portion of the query. The compute nodes process the query graph by first identifying a minimum set of tables, files, and objects stored on the storage nodes required to retrieve data that satisfy the query. Next, the compute nodes selectively assign the identified tables, files, and objects to a leaf vertex of the query graph to optimize retrieving data from the storage nodes. Thereafter, the compute nodes process the retrieved data sets associated with each vertex using separate threads of execution for each vertex of the query graph such that leaf vertices are performed in parallel. The compute nodes then provide a result set.

Abstract: Examples are disclosed that relate to display devices and mounting brackets for securing a bezel to a display device. In one example, a display device comprises a display unit and a bezel comprising at least one pocket. The display device comprises a mounting bracket comprising a display unit attachment portion affixed to the display unit and at least one tongue that extends at least partially into the at least one pocket. Adhesive binds the at least one tongue to at least one surface of the at least one pocket, thereby coupling the bezel to the display unit via the mounting bracket.

Abstract: Executing a query in a disaggregated cluster. A query is received at the disaggregated cluster. A query graph is created based on the query that identifies a hierarchy of vertices, where each vertex is associated with a set of data responsive to at least a portion of the query. The compute nodes process the query graph by first identifying all tables, files, and objects stored on the storage nodes whose access is required to retrieve data that satisfy the query. Next, the compute nodes selectively assign the identified tables, files, and objects to a leaf vertex of the query graph to optimize retrieving data from the storage nodes. Thereafter, the compute nodes process the retrieved data sets associated with each vertex using separate threads of execution for each vertex of the query graph such that leaf vertices are performed in parallel. The compute nodes then provide a result set.

Abstract: Examples are disclosed that relate to display devices and mounting brackets for securing a bezel to a display device. In one example, a display device comprises a display unit and a bezel comprising at least one pocket. The display device comprises a mounting bracket comprising a display unit attachment portion affixed to the display unit and at least one tongue that extends at least partially into the at least one pocket. Adhesive binds the at least one tongue to at least one surface of the at least one pocket, thereby coupling the bezel to the display unit via the mounting bracket.

Abstract: In order to provide a method for producing a composite of a bipolar plate and an MEA, the following is proposed: arranging the bipolar plate in a tool, which has a ferromagnetic or magnetic element, which partially forms the contact surface for the bipolar plate and is designed to be removable from the tool, arranging a membrane electrode assembly on the bipolar plate, arranging a second ferromagnetic or magnetic element on the membrane electrode assembly, removing the membrane electrode assembly and bipolar plate fixed to one another by the two ferromagnetic or magnetic elements, inserting the bipolar plate fixed to the membrane electrode assembly into a second tool, injecting a melt of a polymeric sealing material into the at least one mold cavity of the tool, allowing the melt to solidify, and demolding and removing the composite or the composites. In addition, a composite and a fuel cell stack are disclosed.

Abstract: The subject matter described herein is directed to Ferroportin inhibitor compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds and methods of administering the compounds for prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, particularly iron overload states, such as thalassemia, sickle cell disease and hemochromatosis. The compounds of Formula I and pharmaceutical salts thereof have the following structure: wherein R1, R2, R3, X1, X2, X3, X4, Y1, Y2, and Y3 are as described herein.

Abstract: Example multi-device storage systems, storage devices, and methods provide hosted services on peer storage devices. Storage devices include a storage medium, a logical mapping memory, and a processor for executing hosted services using the logical mapping memory. Each storage device is configured to communicate with peer storage devices over an interconnect fabric. The logical mapping memory includes storage device media logical mapping information configured in continuous logical blocks with a media block size equal to a page programming size of the storage medium. The logical mapping memory also includes host logical mapping information, configured in host logical blocks with a host block size smaller than the media block size, for the peer storage devices.

Abstract: Embodiments described herein relate to apparatus and techniques for aligning and coupling a sensor device to a wearable patch. A shoe apparatus is coupled to the wearable patch. The sensor device is coupled to the shoe apparatus via one or more connectors of the shoe apparatus. As the sensor device is inserted into the shoe apparatus, features of the shoe apparatus enable alignment of the sensor device with the shoe apparatus and the one or more connectors.

Abstract: The invention provides immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions and methods thereof.

Abstract: Embodiments described herein relate to apparatus and techniques for aligning and coupling a sensor device to a wearable patch. A shoe apparatus is coupled to the wearable patch. The sensor device is coupled to the shoe apparatus via one or more connectors of the shoe apparatus. As the sensor device is inserted into the shoe apparatus, features of the shoe apparatus enable alignment of the sensor device with the shoe apparatus and the one or more connectors.

Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD20 or CD22. The invention also relates to chimeric antigen receptor (CAR) specific to CD20 or CD22, vectors encoding the same, and recombinant T or natural killer (NK) cells comprising the CD20 CAR or CD22 CAR. The invention also includes methods of administering a genetically modified T cell or NK cell expressing a CAR that comprises a CD20 or CD22 binding domain.

Abstract: Some implementations of the disclosure are directed to tapping input/output (I/O) data from an industrial control system (ICS) or applying the tapped I/O data to a learned model to perform predictive or prescriptive maintenance. In one implementation, a method comprises: tapping I/O data from a controller of an ICS while the controller executes first control code to control one or more devices of the ICS; transmitting the tapped I/O data over a network to a second system; and executing, via the second system, second control code comprising an original or modified version of all or a subset of the first control code of the ICS, wherein the second control code executes in response to receiving the tapped I/O data. The output of executing the second control code may be provided to a model to predict a future event involving the ICS or to prescribe maintenance of the ICS.

Abstract: A fuel transfer adapter for a fuel cartridge, the fuel transfer adapter comprising: an adapter body; at least one fuel filling channel through said adapter body for the passage of fuel from a valve of the fuel cartridge to a fuel tank of an appliance through a filling port of said fuel tank; a fuel cartridge engaging portion at one end of the adapter body, for engaging the adapter body with the valve of the fuel cartridge; and, a port engaging portion at the other end of the adapter body for releasably engaging with the filling port, whereby the fuel transfer adapter incorporates at least one vent for the passage of vapour from the fuel tank to the atmosphere, said at least one vent being configured, in use, to transfer vapour displaced from the fuel tank by the fuel entering therein to the atmosphere.

Abstract: In order to provide a method for producing a composite of a bipolar plate and an MEA, the following is proposed: arranging the bipolar plate in a tool, which has a ferromagnetic or magnetic element, which partially forms the contact surface for the bipolar plate and is designed to be removable from the tool, arranging a membrane electrode assembly on the bipolar plate, arranging a second ferromagnetic or magnetic element on the membrane electrode assembly, removing the membrane electrode assembly and bipolar plate fixed to one another by the two ferromagnetic or magnetic elements, inserting the bipolar plate fixed to the membrane electrode assembly into a second tool, injecting a melt of a polymeric sealing material into the at least one mold cavity of the tool, allowing the melt to solidify, and demolding and removing the composite or the composites. In addition, a composite and a fuel cell stack are disclosed.

Abstract: Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., tendinopathy, dermatitis, psoriasis, morphea, ichthyosis, Raynaud's syndrome, Darier's disease, scleroderma, cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as neurological conditions/disorders/diseases linked to overexpression of DYRK1A.

Abstract: A wireless transaction request may be received by a vehicle from a retailer. The vehicle may validate that the vehicle is located in proximity to the retailer and may receive confirmation of the request from a vehicle occupant. The vehicle may also initiate a payment for the transaction with a server, responsive to the confirmation of the request and validation of the vehicle location. Communications between the vehicle and the retailer may be performed using Dedicated Short Range Communications (DSRC). The identity of the vehicle occupant may be confirmed using biometric sensors. The payment transaction may be performed using the Automated Clearing House (ACH) electronic network to avoid credit card interchange fees.

Abstract: Methods, systems, and other aspects for reconstructing data and rebuilding a failed storage device in a storage system using one or more functioning compute resources and/or storage resources of the failed storage device. For example, a method may include, responsive to a detection of a failed storage device in a storage system, locating data and redundancy information in functioning storage device(s) in the storage system for reconstructing data of the failed storage device; issuing peer-to-peer commands to the functioning storage device(s) to obtain the data and the redundancy information from the functioning storage device(s); and reconstructing the data of the failed storage device based on the data and the redundancy information obtained from the functioning storage device(s), wherein a functioning compute resource of the failed computing device at least partially performs one or more of the locating, issuing, and reconstructing.

Abstract: To provide a space-saving bipolar plate for a fuel cell comprising an anode plate and a cathode plate, anode gas channels and cathode gas channels lead from main gas ports on opposite sides into an active area and are distributed across the width of said area such that they are subsequently diverted towards an opposite distribution area, and the coolant channels branch in the distribution area and, after branching, are diverted towards the anode gas channels and towards the cathode gas channels and, in each region of overlap with the anode gas channels and the cathode gas channels, are diverted collectively such that the coolant channels lead, together with the anode gas channels and the cathode gas channels, into the active area with no overlap and alternatingly with said anode gas channels and cathode gas channels.

Abstract: Example multi-device storage systems, storage devices, and methods provide hosted services on peer storage devices. Storage devices include a storage medium, a logical mapping memory, and a processor for executing hosted services using the logical mapping memory. Each storage device is configured to communicate with peer storage devices over an interconnect fabric. The logical mapping memory includes storage device media logical mapping information configured in continuous logical blocks with a media block size equal to a page programming size of the storage medium. The logical mapping memory also includes host logical mapping information, configured in host logical blocks with a host block size smaller than the media block size, for the peer storage devices.