Patents by Inventor Brian Abraham

Brian Abraham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10160977
    Abstract: The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: December 25, 2018
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Denes Hnisz, Brian Abraham, Tong Ihn Lee, Richard A. Young
  • Publication number: 20160237490
    Abstract: The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).
    Type: Application
    Filed: October 2, 2015
    Publication date: August 18, 2016
    Inventors: Denes Hnisz, Brian Abraham, Tong Ihn Lee, Richard A. Young
  • Publication number: 20140287932
    Abstract: The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).
    Type: Application
    Filed: October 25, 2013
    Publication date: September 25, 2014
    Inventors: Denes Hnisz, Brian Abraham, Tong Ihn Lee, Richard A. Young
  • Patent number: 8366144
    Abstract: An inflatable cushion for a side of a vehicle is provided, the inflatable cushion having: a first cushion section formed from a first sheet of material secured to a second sheet of material, the first cushion section having a plurality of separate inflatable cells each of which having an inlet opening for receipt of an inflation gas; an internal passageway formed in the first cushion section, the internal passageway linking and fluidly coupling to each of the plurality of separate inflatable cells via the inlet opening of each of the plurality of separate inflatable cells, the internal passageway being formed by an upper portion of the first sheet of material and an upper portion of the second sheet of material; a fabric diffuser member located in the internal passageway, the fabric diffuser member being sealed at one end and open on another end for receipt of an inflation gas, the fabric diffuser being configured to supply the inflation gas to each of the plurality of separate inflatable cells through a plur
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: February 5, 2013
    Assignee: Nxgen Technologies, LLC
    Inventors: Michael Fink, Ryan T. Pinsenschaum, Douglas S. Weston, Dayne B. Hassett, Brian Abraham
  • Patent number: 8240708
    Abstract: An inflatable cushion for a side of a vehicle, the inflatable cushion having: a first cushion section formed from a first sheet of material secured to a second sheet of material, the first cushion section having a plurality of separate inflatable cells each of which having an inlet opening for receipt of an inflation gas; an internal passageway formed in the first cushion section, the internal passageway linking and fluidly coupling to each of the plurality of separate inflatable cells via the inlet opening of each of the plurality of separate inflatable cells, the internal passageway being formed by an upper portion of the first sheet of material and an upper portion of the second sheet of material; a fabric diffuser member secured in the internal passageway, the fabric diffuser member being configured to supply the inflation gas to each of the plurality of separate inflatable cells; and means for restricting fluid flow between the plurality of inflatable cells by limiting fluid flow between an exterior port
    Type: Grant
    Filed: May 14, 2010
    Date of Patent: August 14, 2012
    Assignee: Nxgen Technologies, LLC
    Inventors: Michael Fink, Ryan T. Pinsenschaum, Douglas S. Weston, Dayne B. Hassett, Brian Abraham, Ever E. Luna, Raul A. Hernandez
  • Publication number: 20110062689
    Abstract: An inflatable cushion for a side of a vehicle is provided, the inflatable cushion having: a first cushion section formed from a first sheet of material secured to a second sheet of material, the first cushion section having a plurality of separate inflatable cells each of which having an inlet opening for receipt of an inflation gas; an internal passageway formed in the first cushion section, the internal passageway linking and fluidly coupling to each of the plurality of separate inflatable cells via the inlet opening of each of the plurality of separate inflatable cells, the internal passageway being formed by an upper portion of the first sheet of material and an upper portion of the second sheet of material; a fabric diffuser member located in the internal passageway, the fabric diffuser member being sealed at one end and open on another end for receipt of an inflation gas, the fabric diffuser being configured to supply the inflation gas to each of the plurality of separate inflatable cells through a plur
    Type: Application
    Filed: June 18, 2010
    Publication date: March 17, 2011
    Inventors: Michael Fink, Ryan T. Pinsenschaum, Douglas S. Weston, Dayne B. Hassett, Brian Abraham
  • Publication number: 20110057424
    Abstract: An inflatable cushion for a side of a vehicle, the inflatable cushion having: a first cushion section formed from a first sheet of material secured to a second sheet of material, the first cushion section having a plurality of separate inflatable cells each of which having an inlet opening for receipt of an inflation gas; an internal passageway formed in the first cushion section, the internal passageway linking and fluidly coupling to each of the plurality of separate inflatable cells via the inlet opening of each of the plurality of separate inflatable cells, the internal passageway being formed by an upper portion of the first sheet of material and an upper portion of the second sheet of material; a fabric diffuser member secured in the internal passageway, the fabric diffuser member being configured to supply the inflation gas to each of the plurality of separate inflatable cells; and means for restricting fluid flow between the plurality of inflatable cells by limiting fluid flow between an exterior port
    Type: Application
    Filed: May 14, 2010
    Publication date: March 10, 2011
    Inventors: Michael Fink, Ryan T. Pinsenschaum, Douglas S. Weston, Dayne B. Hassett, Brian Abraham, Ever E. Luna, Raul A. Hernandez
  • Publication number: 20050258624
    Abstract: A vehicle seat in accordance with an exemplary embodiment is provided. The vehicle seat includes an air bag module coupled to a vehicle seat frame, the air bag module having an inflatable cushion. The vehicle seat further includes a seat cover configured to cover at least a portion of the air bag module. The seat cover has a deployment opening defining a first edge and a second edge adjacent the first edge. The vehicle seat further includes first and second interlocking members attached to the seat cover proximate the first and second edges, respectively. The first interlocking member is configured to interlock with the second interlocking member to thereby close the deployment opening. The first and second interlocking members extend substantially an entire length of the first and second edges. The first and second interlocking members disengage from one another upon deployment of the inflatable cushion to allow the inflatable cushion to pass through the deployment opening.
    Type: Application
    Filed: May 21, 2004
    Publication date: November 24, 2005
    Inventors: Brian Abraham, Rebecca Bevak, Margaret Fisher, Michelle Frank