Abstract: Disclosed are methods, devices, and systems for treatment of an abnormal wound healing response. The methods, devices, and systems can be used to treat solid ulcerated tissue, such as diabetic foot ulcers (DFUs), arthritic tissue, muscle soreness, joint pain, varicose veins, obesity, and peripheral artery disease. Additionally, the methods, devices, and systems can promote the healing of xenograft, allograft, autograft, or engineered tissue following reconstruction surgery. The methods, devices, and systems include the ability to determine an optimal set of pulse parameters that are specific to wound healing. In embodiments, the methods, devices, and systems include components for guiding the user on electrode placement based on anatomical or electrical measurements, delivering a custom series of electric pulses, applying heat, and using feedback from physiologic measurements to control the device.

Abstract: A therapeutic apparatus for treating damaged tissue on a limb or body of a subject includes a wearable adapted to cover and be secured to the limb or body of a subject over damaged tissue. The wearable being configured to reduce pressure on the damaged tissue and adapted to deliver one or more treatments selected from the group consisting of heat, oxygen, electrical current, and light to the damaged tissue.

Abstract: A therapeutic apparatus for treating damaged tissue on a limb or body of a subject includes a wearable adapted to cover and be secured to the limb or body of a subject over damaged tissue. The wearable being configured to reduce pressure on the damaged tissue and adapted to deliver one or more treatments selected from the group consisting of heat, oxygen, electrical current, and light to the damaged tissue.

Abstract: An apparatus has a hub including a water inlet for receiving source water, a water outlet for discharging ozonated water, and an interface between the water inlet and the water outlet. The apparatus also has a cartridge including an electrolytic cell for ozonating the source water. The electrolytic cell has a cathode, an anode comprising diamond, and a membrane between the cathode and the anode. The electrolytic cell is configured to flow source water through both the cathode and the anode. The cartridge further includes at least one cartridge port for removably coupling with the interface on the hub. The at least one cartridge port and the interface are configured to flow source water from the hub into the electrolytic cell and to flow ozonated water from the electrolytic cell into the hub.

Abstract: Disclosed are methods, devices, and systems for treatment of an abnormal wound healing response. The methods, devices, and systems can be used to treat solid ulcerated tissue, such as diabetic foot ulcers (DFUs), arthritic tissue, muscle soreness, joint pain, varicose veins, obesity, and peripheral artery disease. Additionally, the methods, devices, and systems can promote the healing of xenograft, allograft, autograft, or engineered tissue following reconstruction surgery. The methods, devices, and systems include the ability to determine an optimal set of pulse parameters that are specific to wound healing. In embodiments, the methods, devices, and systems include components for guiding the user on electrode placement based on anatomical or electrical measurements, delivering a custom series of electric pulses, applying heat, and using feedback from physiologic measurements to control the device.

Abstract: Disclosed are methods, devices, and systems for treatment of an abnormal wound healing response. The methods, devices, and systems can be used to treat solid ulcerated tissue, such as diabetic foot ulcers (DFUs), arthritic tissue, muscle soreness, joint pain, varicose veins, obesity, and peripheral artery disease. Additionally, the methods, devices, and systems can promote the healing of xenograft, allograft, autograft, or engineered tissue following reconstruction surgery. The methods, devices, and systems include the ability to determine an optimal set of pulse parameters that are specific to wound healing. In embodiments, the methods, devices, and systems include components for guiding the user on electrode placement based on anatomical or electrical measurements, delivering a custom series of electric pulses, applying heat, and using feedback from physiologic measurements to control the device.

Abstract: A therapeutic apparatus for treating damaged tissue on a limb or body of a subject includes a wearable adapted to cover and be secured to the limb or body of a subject over damaged tissue. The wearable being configured to reduce pressure on the damaged tissue and adapted to deliver one or more treatments selected from the group consisting of heat, oxygen, electrical current, and light to the damaged tissue.

Abstract: Disclosed are methods, devices, and systems for treatment of an abnormal wound healing response. The methods, devices, and systems can be used to treat solid ulcerated tissue, such as diabetic foot ulcers (DFUs), arthritic tissue, muscle soreness, joint pain, varicose veins, obesity, and peripheral artery disease. Additionally, the methods, devices, and systems can promote the healing of xenograft, allograft, autograft, or engineered tissue following reconstruction surgery. The methods, devices, and systems include the ability to determine an optimal set of pulse parameters that are specific to wound healing. In embodiments, the methods, devices, and systems include components for guiding the user on electrode placement based on anatomical or electrical measurements, delivering a custom series of electric pulses, applying heat, and using feedback from physiologic measurements to control the device.

Abstract: An apparatus has a hub including a water inlet for receiving source water, a water outlet for discharging ozonated water, and an interface between the water inlet and the water outlet. The apparatus also has a cartridge including an electrolytic cell for ozonating the source water. The electrolytic cell has a cathode, an anode comprising diamond, and a membrane between the cathode and the anode. The electrolytic cell is configured to flow source water through both the cathode and the anode. The cartridge further includes at least one cartridge port for removably coupling with the interface on the hub. The at least one cartridge port and the interface are configured to flow source water from the hub into the electrolytic cell and to flow ozonated water from the electrolytic cell into the hub.

Abstract: An apparatus has a hub including a water inlet for receiving source water, a water outlet for discharging ozonated water, and an interface between the water inlet and the water outlet. The apparatus also has a cartridge including an electrolytic cell for ozonating the source water. The electrolytic cell has a cathode, an anode comprising diamond, and a membrane between the cathode and the anode. The electrolytic cell is configured to flow source water through both the cathode and the anode. The cartridge further includes at least one cartridge port for removably coupling with the interface on the hub. The at least one cartridge port and the interface are configured to flow source water from the hub into the electrolytic cell and to flow ozonated water from the electrolytic cell into the hub.