Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.

Abstract: Provided herein are binding molecules, such as those that recognize or bind a peptide epitope of a cancer antigen, such as expressed on a cancer cell, including cells infected with human papilloma virus (HPV) or that contain HPV DNA sequences and/or those that recognize or bind a peptide epitope of HPV 16 E6 or E7, in the context of a major histocompatibility complex (MHC) molecule. Among the provided binding molecules are T cell receptors (TCRs) or antibodies, including antigen-binding fragments thereof, that bind or recognize such peptide epitopes. The present disclosure further relates to engineered cells comprising such binding molecules, e.g., TCRs or antibodies (and chimeric antigen receptors containing the antibodies), and uses thereof in adoptive cell therapy.

Abstract: Provided herein are binding molecules, such as those that recognize or bind a peptide epitope of a cancer antigen, such as expressed on a cancer cell, including cells infected with human papilloma virus (HPV) or that contain HPV DNA sequences and/or those that recognize or bind a peptide epitope of HPV 16 E6 or E7, in the context of a major histocompatibility complex (MHC) molecule. Among the provided binding molecules are T cell receptors (TCRs) or antibodies, including antigen-binding fragments thereof, that bind or recognize such peptide epitopes. The present disclosure further relates to engineered cells comprising such binding molecules, e.g., TCRs or antibodies (and chimeric antigen receptors containing the antibodies), and uses thereof in adoptive cell therapy.

Abstract: Provided are receptor tyrosine kinase-like orphan receptor 1 (ROR1)-binding molecules, in particular, to human antibodies specific for ROR1, including antibody fragments. The present disclosure further relates to recombinant receptors, including chimeric antigen receptors (CARs) that contain such antibodies or fragments, and polynucleotides that encode the antibodies, antigen-binding fragments or receptors specific for ROR1. The disclosure further relates to genetically engineered cells, containing such ROR1-binding proteins and receptors, and related methods and uses thereof in adoptive cell therapy.

Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.

Abstract: Provided herein are binding molecules, such as those that recognize or bind a peptide epitope of a cancer antigen, such as expressed on a cancer cell, including cells infected with human papilloma virus (HPV) or that contain HPV DNA sequences and/or those that recognize or bind a peptide epitope of HPV 16 E6 or E7, in the context of a major histocompatibility complex (MHC) molecule. Among the provided binding molecules are T cell receptors (TCRs) or antibodies, including antigen-binding fragments thereof, that bind or recognize such peptide epitopes. The present disclosure further relates to engineered cells comprising such binding molecules, e.g., TCRs or antibodies (and chimeric antigen receptors containing the antibodies), and uses thereof in adoptive cell therapy.

Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.

Abstract: A method and system for customizing access to content aggregated from multiple sources. A method includes selecting at least two content items, where the at least two content items are the result of a search from at least two sources, saving the at least two content items in a container, determining a channel, mapping the container to the channel and allowing access to the at least two content items in the container via the channel.

Abstract: A method and apparatus for a user to interface with a mobile computing device is disclosed.

Abstract: Techniques to generate information using a remote control are described. An apparatus may comprise a user interface module to receive movement information representing handwriting from a remote control, and to perform handwriting recognition operations using the movement information. Other embodiments are described and claimed.

Abstract: A user interface with software lensing may be described. An apparatus may comprise a user interface module to display information objects for an electronic program guide, receive movement information from a remote control, and move a pointer in response to the movement information. The apparatus may further include a media lensing module to increase a first information object to a first size when the pointer approaches or coincides with the first information object. Other embodiments are described and claimed.

Abstract: A user interface for a media device may be described. An apparatus may comprise a user interface module to receive movement information representing handwriting from a remote control, convert the handwriting into characters, and display the characters in a first viewing layer with graphical objects in a second viewing layer. Other embodiments are described and claimed.

Abstract: An embodiment of the present invention is a technique to dynamically swap processor cores. A first core has a first instruction set. The first core executes a program at a first performance level. The first core stops executing the program when a triggering event occurs. A second core has a second instruction set compatible with the first instruction set and has a second performance level different than the first performance level. The second core is in a power down state when the first core is executing the program. A circuit powers up the second core after the first core stops executing the program such that the second core continues executing the program at the second performance level.

Abstract: A computing system is described that includes a main system bus that remains active while said computing system operates within a non main CPU/OS based operational state. The computing system also includes a controller that operates functional tasks while the computing system is within the non main CPU/OS based operational state. The computing system also includes an I/O unit coupled to the main system bus that remains active while the computing system operates within the non main CPU/OS based operational state.

Abstract: A method is described that involves operating a computing system within a normal on state and transitioning from the normal on state to a main CPU/OS based state. In the main CPU/OS based state one or more components of the computing system are inactivated so as to cause the computing system to consume less power in the main CPU/OS based state than in the normal on state. The computing system is able to execute software application routines on a main CPU and a main OS of the computing system while in the main CPU/OS based state.

Abstract: A method and system for reducing power consumption of a computer system by allocating memory pages that are associated with lower memory address before those associated with higher memory addresses. Memory elements that do not include any allocated memory pages and that are positioned at a higher address than a threshold address may have its power consumption reduced when the computer system enters a low power consumption state.

Abstract: A method is described that involves operating a computing system within a normal on state and transitioning from the normal on state to a main CPU/OS based state. In the main CPU/OS based state one or more components of the computing system are inactivated so as to cause the computing system to consume less power in the main CPU/OS based state than in the normal on state. The computing system is able to execute software application routines on a main CPU and a main OS of the computing system while in the main CPU/OS based state.

Abstract: Embodiments of the present invention can make data from a primary system of a computer available to an extended mobile access module embedded in the computer.

Abstract: An apparatus comprising a usage analysis engine may be capable of receiving data on the environment of the apparatus, the data used to create a profile. The usage analysis engine may be further capable of correlating a present profile with previous profiles. The apparatus may take some action or prohibits some action based on the correlation of the present profile with the previous profiles provided by the usage analysis engine and may take no action based on lack of correlation of the present profile with the previous profiles provided by the usage analysis engine.

Abstract: A method, apparatus and system enable users to utilize their personal computers (“PCs”) to manage incoming cell phone calls. A cell phone may be coupled to a PC, and the PC may be configured to notify the user of incoming calls or to automatically respond to incoming calls. If the user is notified, an application on the PC may enable the user to view information associated with the call, and select a response option to handle the call. If the PC is configured to respond automatically, the PC may select an appropriate response for the incoming call.