Patents by Inventor Brian Biehs

Brian Biehs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating hedgehog-related diseases with an anti-LGR5 antibody
    Patent number: 10246515
    Abstract: Provided herein are methods of using anti-LGR5 antibodies, for example, for treating a hedgehog-related disease including basal cell carcinoma.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: April 2, 2019
    Assignee: Genentech, Inc.
    Inventors: Frederic J. De Sauvage, Brian Biehs
  • Notch pathway inhibition
    Patent number: 9914774
    Abstract: The invention provides Notch pathway inhibition with reduced toxicity.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: March 13, 2018
    Assignees: Genentech, Inc., The Regents of the University of California
    Inventors: Fred de Sauvage, Christian Siebel, Brian Biehs, Hua Tian, Ophir Klein
  • METHODS OF USING ANTI-LGR5 ANTIBODIES
    Publication number: 20170002085
    Abstract: Provided herein are methods of using anti-LGR5 antibodies, for example, for treating a hedgehog-related disease including basal cell carcinoma.
    Type: Application
    Filed: March 15, 2016
    Publication date: January 5, 2017
    Applicant: Genentech, Inc.
    Inventors: FREDERIC J. DE SAUVAGE, BRIAN BIEHS
  • NOTCH PATHWAY INHIBITION
    Publication number: 20160068596
    Abstract: The invention provides Notch pathway inhibition with reduced toxicity.
    Type: Application
    Filed: July 9, 2015
    Publication date: March 10, 2016
    Inventors: Fred de Sauvage, Christian Siebel, Brian Biehs, Hua Tian
  • LIQUID CULTURING OF EPITHELIAL STEM CELLS
    Publication number: 20150361392
    Abstract: Provided herein is a method of culturing epithelial stem cells and tissue fragments comprising epithelial stem cells in liquid cultures.
    Type: Application
    Filed: August 25, 2015
    Publication date: December 17, 2015
    Applicant: GENENTECH, INC.
    Inventor: Brian Biehs