Abstract: A self-calibrating monitoring system based on microdialysis for measurement of a body analyte is disclosed. In one embodiment, perfusate containing a known concentration of body analyte is mixed with an enzyme solution after passing through a microdialysis needle and instead of passing through the microdialysis needle to measure the body analyte and to calibrate the analysis chamber that measures the body analyte.

Abstract: A method and a system for preserving patient specific data in implantable pulse generator systems. A communication link is established with a first implantable pulse generator. Electronic cardiac data contained within the first implantable pulse generator is retrieved through the communication link. The electronic cardiac data is then electronically downloaded to a second implantable pulse generator. Prior to downloading, the electronic cardiac data can be formatted into a format compatible with the second implantable pulse generator.

Abstract: An implantable atrial defibrillator for converting atrial arrhythmias into normal sinus rhythm includes a patient activated mode, a programmable safety timer, and means for deactivating the patient activated mode. The programmable safety timer starts counting down when AF is detected. If the safety timer times out before the patient activates delivery of an atrial defibrillation shock, the device will deactivate the atrial defibrillation function, and will not allow an atrial defibrillation shock to be delivered until the physician reactivates it with a programmer. This allows the physician to administer anticoagulants to the patient prior to atrial cardioversion. The preferred length of time between AF detection and lock out of the atrial defibrillation function is 24 hours.