Patents by Inventor Brian Brandt

Brian Brandt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210284709
    Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.
    Type: Application
    Filed: September 28, 2018
    Publication date: September 16, 2021
    Applicants: Juno Therapeutics, Inc., Editas Medicine, Inc.
    Inventors: Cameron BRANDT, Brian BELMONT, Christopher BORGES, Stephen Michael BURLEIGH, Alexandra CROFT, Stephen Jacob GOLDFLESS, David Jeffrey HUSS, Yue JIANG, Timothy G. JOHNSTONE, David KOPPSTEIN, Hieu NGUYEN, Christopher Heath NYE, Haley PEPER, Blythe D. SATHER, Sonia TIMBERLAKE, Dean Y. TOY, Queenie VONG, Gordon Grant WELSTEAD, James SISSONS
  • Patent number: 9220145
    Abstract: An illumination system detects a peak value of a voltage of a transformer supplying an LED module by analyzing the current value of the voltage and an on-time of the voltage. Based on the detected peak value, a property of the illumination system is adjusted.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: December 22, 2015
    Assignee: TerraLUX, Inc.
    Inventor: Brian Brandt
  • Patent number: 9192011
    Abstract: A bleed circuit is applied to a transformer based on a bleed-on time and a bleed-off time determined by monitoring an output voltage waveform of the transformer.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: November 17, 2015
    Assignee: TerraLUX, Inc.
    Inventor: Brian Brandt
  • Publication number: 20150145441
    Abstract: A bleed circuit is applied to a transformer based on a bleed-on time and a bleed-off time determined by monitoring an output voltage waveform of the transformer.
    Type: Application
    Filed: October 22, 2014
    Publication date: May 28, 2015
    Inventor: Brian Brandt
  • Publication number: 20150123567
    Abstract: An illumination system detects a peak value of a voltage of a transformer supplying an LED module by analyzing the current value of the voltage and an on-time of the voltage. Based on the detected peak value, a property of the illumination system is adjusted.
    Type: Application
    Filed: November 5, 2014
    Publication date: May 7, 2015
    Inventor: Brian Brandt
  • Patent number: 8907588
    Abstract: An illumination system detects a peak value of a voltage of a transformer supplying an LED module by analyzing the current value of the voltage and an on-time of the voltage. Based on the detected peak value, a property of the illumination system is adjusted.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: December 9, 2014
    Assignee: Terralux, Inc.
    Inventor: Brian Brandt
  • Patent number: 8896231
    Abstract: A bleed circuit is applied to a transformer based on a bleed-on time and a bleed-off time determined by monitoring an output voltage waveform of the transformer.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: November 25, 2014
    Assignee: TerraLUX, Inc.
    Inventor: Brian Brandt
  • Patent number: 8763606
    Abstract: The present disclosure provides an inhaler having a vibration element for aerosolizing medicament contained in a blister pack, wherein a plurality of individual blister packs are arranged in a rotary cassette that fits within a housing, and wherein the individual blister packs are dragged up into a clamping position between the vibration element and a piercing element. The motion of the blister pack is controlled by a rotary disk within the housing which further coordinates the movement of the piercing and vibrating elements for the piercing and deaggregation, respectively, of the individual blister packs.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: July 1, 2014
    Assignee: Microdose Therapeutx, Inc.
    Inventors: Kent D. Mosier, Brian Brandt-Madsen, Steen G. Lassen, Morten E. Andersen, Jan Olesen
  • Publication number: 20130187564
    Abstract: An illumination system detects a peak value of a voltage of a transformer supplying an LED module by analyzing the current value of the voltage and an on-time of the voltage. Based on the detected peak value, a property of the illumination system is adjusted.
    Type: Application
    Filed: December 14, 2012
    Publication date: July 25, 2013
    Inventor: Brian Brandt
  • Publication number: 20130154515
    Abstract: A bleed circuit is applied to a transformer based on a bleed-on time and a bleed-off time determined by monitoring an output voltage waveform of the transformer.
    Type: Application
    Filed: December 17, 2012
    Publication date: June 20, 2013
    Inventor: Brian Brandt
  • Patent number: 8295902
    Abstract: A tissue electrode assembly includes a membrane configured to form an expandable, conformable body that is deployable in a patient. The assembly further includes a flexible circuit positioned on a surface of the membrane and comprising at least one base substrate layer, at least one insulating layer and at least one planar conducting layer. An electrically-conductive electrode covers at least a portion of the flexible circuit and a portion of the surface of the membrane not covered by the flexible circuit, wherein the electrically-conductive electrode is foldable upon itself with the membrane to a delivery conformation having a diameter suitable for minimally-invasive delivery of the assembly to the patient.
    Type: Grant
    Filed: November 11, 2009
    Date of Patent: October 23, 2012
    Assignee: Shifamed Holdings, LLC
    Inventors: Amr Salahieh, Jonah Lepak, Emma Leung, Brian Brandt, John P. Claude
  • Publication number: 20110144736
    Abstract: The present invention is directed to a flexible expandable stent for implantation in a body lumen, such as a coronary artery. The stent generally includes a series of metallic cylindrical rings longitudinally aligned on a common axis of the stent and interconnected by a series of links which be polymeric or metallic. Varying configurations and patterns of the links provides longitudinal and flexural flexibility to the stent while maintaining sufficient column strength to space the cylindrical rings along the longitudinal axis. The metallic material forming the rings provides the necessary radial stiffness.
    Type: Application
    Filed: November 16, 2010
    Publication date: June 16, 2011
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Santosh Prabhu, Brian Brandt, Henjen Ho, Kyle Marie Krueger, Grayson Morris, Carla Rosa Pienknagura
  • Publication number: 20100294278
    Abstract: The present disclosure provides an inhaler having a vibration element for aerosolizing medicament contained in a blister pack, wherein a plurality of individual blister packs are arranged in a rotary cassette that fits within a housing, and wherein the individual blister packs are dragged up into a clamping position between the vibration element and a piercing element. The motion of the blister pack is controlled by a rotary disk within the housing which further coordinates the movement of the piercing and vibrating elements for the piercing and deaggregation, respectively, of the individual blister packs.
    Type: Application
    Filed: May 21, 2010
    Publication date: November 25, 2010
    Inventors: Kent D. Mosier, Brian Brandt-Madsen, Steen G. Lassen, Morten E. Andersen, Jan Olesen
  • Patent number: 7824443
    Abstract: An apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes a replacement heart valve implant comprising a valve and an expandable anchor; and a deployment tool adapted to endovascularly deliver the replacement heart valve implant to an implant site within the patient, the deployment tool comprising an actuator adapted to exert an axially directed force on the anchor. The invention also provides a method for endovascularly replacing a heart valve of a patient. In some embodiments, the method includes the steps of endovascularly delivering a replacement heart valve implant having a valve and an anchor to an implant site within the patient; and applying an axially directed force from an actuator outside of the patient to the anchor. In invention also provides deployment tools for performing the method.
    Type: Grant
    Filed: February 2, 2006
    Date of Patent: November 2, 2010
    Assignee: Sadra Medical, Inc.
    Inventors: Amr Salahieh, Dwight Morejohn, Ulrich R. Haug, Brian Brandt, Hans Valencia, Tom Saul
  • Publication number: 20070244552
    Abstract: Methods and devices for assessing the operation of a replacement heart valve. The method includes endovascularly delivering a replacement heart valve to a vicinity of a heart valve in an unexpanded configuration, and assessing the operation of the replacement heart valve in the vicinity of the heart valve before fully expanding the replacement heart valve. Methods and devices for assessing the location of a replacement heart valve. The method includes endovascularly delivering a replacement heart valve to a vicinity of the heart valve in an unexpanded configuration, expanding the replacement heart valve to a partially deployed configuration, and assessing the location of the replacement heart valve in the vicinity of the heart valve before fully expanding the replacement heart valve.
    Type: Application
    Filed: April 4, 2007
    Publication date: October 18, 2007
    Inventors: Amr Salahieh, Brian Brandt, Dwight Morejohn, Ulrich Haug, Jean-Pierre Dueri, Hans Valencia, Robert Geshlider, Jeff Krolik
  • Publication number: 20070239251
    Abstract: The present invention is directed to a flexible expandable stent for implantation in a body lumen, such as a coronary artery. The stent generally includes a series of metallic cylindrical rings longitudinally aligned on a common axis of the stent and interconnected by a series of links which be polymeric or metallic. Varying configurations and patterns of the links provides longitudinal and flexural flexibility to the stent while maintaining sufficient column strength to space the cylindrical rings along the longitudinal axis. The metallic material forming the rings provides the necessary radial stiffness.
    Type: Application
    Filed: June 13, 2007
    Publication date: October 11, 2007
    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
    Inventors: Santosh Prabhu, Brian Brandt, Henjen Ho, Kyle Krueger, Grayson Morris, Carla Pienknagura
  • Publication number: 20070203503
    Abstract: The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.
    Type: Application
    Filed: February 14, 2007
    Publication date: August 30, 2007
    Inventors: Amr Salahieh, Hans Valencia, Brian Brandt, Claudio Argento, Ulrich Haug, Jean-Pierre Dueri, Daniel Hildebrand, Dwight Morejohn, Tom Saul
  • Publication number: 20070010877
    Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
    Type: Application
    Filed: September 14, 2006
    Publication date: January 11, 2007
    Inventors: Amr Salahieh, Jean-Pierre Dueri, Hans Valencia, Daniel Hildebrand, Brian Brandt, Dwight Morejohn, Claudio Argento, Tom Saul, Ulrich Haug
  • Publication number: 20070010876
    Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulic or non-pneumatic actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor.
    Type: Application
    Filed: September 14, 2006
    Publication date: January 11, 2007
    Inventors: Amr Salahieh, Brian Brandt, Dwight Morejohn, Ulrich Haug, Jean-Pierre Dueri, Hans Valencia, Robert Geshlider, Jeff Krolik
  • Publication number: 20060173524
    Abstract: An apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes a replacement heart valve implant comprising a valve and an expandable anchor; and a deployment tool adapted to endovascularly deliver the replacement heart valve implant to an implant site within the patient, the deployment tool comprising an actuator adapted to exert an axially directed force on the anchor. The invention also provides a method for endovascularly replacing a heart valve of a patient. In some embodiments, the method includes the steps of endovascularly delivering a replacement heart valve implant having a valve and an anchor to an implant site within the patient; and applying an axially directed force from an actuator outside of the patient to the anchor. In invention also provides deployment tools for performing the method.
    Type: Application
    Filed: February 2, 2006
    Publication date: August 3, 2006
    Inventors: Amr Salahieh, Dwight Morejohn, Ulrich Haug, Brian Brandt, Hans Valencia, Tom Saul