Patents by Inventor Brian Brown

Brian Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11143723
    Abstract: A flexible coil with improved tolerance for overlapping antennas and with reduced susceptibility to the introduction of image artifacts as a result of overlapping antennas utilizes antennas with multiple conductors extending in parallel for the length of the antenna. Each conductor is connected to the other conductor at each end creating parallel conduction paths for the length of the antenna. The parallel conduction paths reduce the resistance of the antenna which, in turn, improves the quality factor of the antenna. The improved quality factor results in antennas that are less susceptible to image artifacts being induced in the antenna due to coupling from an overlapping antenna.
    Type: Grant
    Filed: January 8, 2020
    Date of Patent: October 12, 2021
    Assignee: NEOCOIL, LLC
    Inventor: Brian Brown
  • Publication number: 20210308636
    Abstract: A hemp extract-based emulsion and method for forming includes cannabinoids, including at least tetrahydrocannabinol and cannabigerol, at least one emulsifier, and an aqueous phase. An emulsion of at least the tetrahydrocannabinol is present as droplets suspended in the aqueous phase.
    Type: Application
    Filed: April 1, 2021
    Publication date: October 7, 2021
    Inventor: Brian Brown
  • Publication number: 20210208220
    Abstract: A flexible coil with improved tolerance for overlapping antennas and with reduced susceptibility to the introduction of image artifacts as a result of overlapping antennas utilizes antennas with multiple conductors extending in parallel for the length of the antenna. Each conductor is connected to the other conductor at each end creating parallel conduction paths for the length of the antenna. The parallel conduction paths reduce the resistance of the antenna which, in turn, improves the quality factor of the antenna. The improved quality factor results in antennas that are less susceptible to image artifacts being induced in the antenna due to coupling from an overlapping antenna.
    Type: Application
    Filed: January 8, 2020
    Publication date: July 8, 2021
    Inventor: Brian Brown
  • Patent number: 11044896
    Abstract: This invention relates to a transgenic non-human mammal whose genome comprises a polynucleotide sequence encoding a T cell receptor that is specific to a fluorescent protein, where the T cell of the non-human mammal comprises the T cell receptor. The present invention also relates to an isolated T cell from the transgenic non-human mammal of the present invention, an isolated T cell comprising an expression construct comprising a polynucleotide sequence that encodes a T cell receptor that is specific to a fluorescent protein, methods of making transgenic non-human mammals comprising T cell receptors that are specific to a fluorescent protein, a method of depleting cells in a non-human mammal using isolated T cells that encode a T cell receptor that is specific to a target protein, and a method of characterizing a T cell response to an agent.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: June 29, 2021
    Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Brian Brown, Judith Agudo
  • Publication number: 20210161460
    Abstract: Apparatus for determining the electrical conductivity of target cervical tissue using magnetic impedance spectroscopy comprising: an excitation coil for producing a magnetic field which is capable of inducing currents in the target cervical tissue; a gradiometer for detecting perturbations in said magnetic field caused by said induced currents, the gradiometer including screening means for minimising sensitivity to tissues other than the target tissue; processing means for determining an electrical conductivity of said target cervical tissue from said perturbations.
    Type: Application
    Filed: December 21, 2016
    Publication date: June 3, 2021
    Inventors: Brian BROWN, Dilichukwu ANUMBA
  • Publication number: 20210140164
    Abstract: A form for a plastic lined septic system distribution box is configured to receive a fill material. The form includes a jacket, a plastic core, a plastic inlet ring, and a plastic outlet ring. The jacket defines an exterior wall and exterior floor of the distribution box. The core defines an interior wall interior floor of the distribution box. The inlet portal ring and outlet portal ring extend between the core interior wall and the jacket exterior wall. The core and jacket are arranged to leave a space therebetween to receive the fill material, and the core is configured to serve as the interior wall and interior floor of the distribution box and to line the fill material for the distribution box during use.
    Type: Application
    Filed: June 8, 2017
    Publication date: May 13, 2021
    Inventor: Brian Brown
  • Publication number: 20210110952
    Abstract: A robotic system for laying out a specified wiring harness. A robotic arm is configured to arrange a plurality of wire segments along the harness support surface. A system controller is configured to direct the robotic arm to arrange each of the plurality of wire segments on the harness support surface along a specified wire route. A preparation device can label one or both ends of each wire segment as they are being laid out on the support surface. The labeler can automatically apply adhesive labels as flags at selected locations along the length of the wire segment. In a method of making a wiring harness, the robotic arm positions pins on a harness support surface to define wire routes and then arranges at least one wire segment on the harness support surface along each of the wire routes.
    Type: Application
    Filed: September 19, 2020
    Publication date: April 15, 2021
    Inventors: Brian Brown, Michael Wescott, Alexander VanPelt
  • Publication number: 20210070061
    Abstract: An inkjet printhead includes: a fluid manifold having a base defining a plurality of fluid outlets and printhead chips attached to the base. Each printhead chip receives printing fluid from a set of the fluid outlets. All fluid outlets are flared with a respect to a width dimension of the printhead chips for facilitating removal of air bubbles.
    Type: Application
    Filed: November 18, 2020
    Publication date: March 11, 2021
    Inventors: Garry Jackson, Norman Berry, Michael Hudson, Brian Brown, Samuel Mallinson, Geordie McBain
  • Patent number: 10932323
    Abstract: A reactor for chemical vapor deposition is equipped with an IR radiation compensating susceptor assembly that supports one or more semiconductor substrates above linear IR heater lamps arranged in a parallel array. A set of primary IR radiation reflectors beneath the lamps directs IR radiation back toward the susceptor in a pattern selected to provide uniform IR irradiation of the susceptor assembly to thereby uniformly heat the substrates. Secondary IR shield reflectors may be provided in selected patterns on the underside of the susceptor assembly as a fine tuning measure to direct IR radiation away from the assembly in a controlled pattern. The combined IR radiation reflectors have an IR signature that compensates for any non-uniform heating profile created by the linear IR heater lamp array. The heating profile of the lamp array might also be tailored in order to reduce the amount of compensation required to be supplied by the IR reflectors.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: February 23, 2021
    Assignee: ALTA DEVICES, INC.
    Inventors: Brian Burrows, Abril Cabreros, David M. Ishikawa, Brian Brown, Alexander Lerner
  • Patent number: 10905330
    Abstract: The subject matter disclosed herein describes an improved MR imaging system for breast tissue. The MR imaging system includes a pair of antenna coil arrays that are movable with respect to a base plate on which the coil arrays are mounted. A fixed coil array may also be mounted in a medial location on the base plate. The MR imaging system provides an abdominal support structure and a head support structure to position a patient in a prone position over the movable and fixed coil arrays. An additional support pad may be provided on the upper surface of the medial coil to support the patient's chest. Each of the movable antenna coil arrays may be moved laterally along the base plate to adjust the space between the two arrays. Once adjusted, each of the movable antenna coil arrays may be secured in the adjusted position to immobilize the breast tissue.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: February 2, 2021
    Assignee: NeoCoil, Inc.
    Inventors: Kyle Johnson, Brian Brown, Chris Salimes, Emad Abdelsalam
  • Patent number: 10870287
    Abstract: A method of inkjet printing includes the steps of: (i) delivering ink to a printhead manifold having a longitudinal ink channel, one or printhead chips mounted to a floor of the printhead manifold and in fluid communication with the longitudinal ink channel, and a plurality of sealed air cavities positioned over the longitudinal ink channel for dampening pressure fluctuations in the ink; (ii) printing from the printhead chips; and (iii) replenishing the air cavities with air.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: December 22, 2020
    Inventors: Garry Jackson, Norman Berry, Michael Hudson, Brian Brown, Samuel Mallinson, Geordie McBain
  • Publication number: 20200326393
    Abstract: A shoulder coil for use in MR imaging includes a rigid housing configured to be positioned on the posterior portion of the shoulder and a flexible coil assembly, mounted to the rigid housing, where the flexible coil assembly is repositionable with respect to the first housing. The flexible coil assembly may be folded outward to facilitate loading of the patient or positioning of the shoulder coil with respect to the patient and folded inward to rest on the shoulder of the patient during imaging. The shoulder coil is positioned at an angle with respect to the shoulder to extend from the superior surface to the lateral surface of the shoulder. Antennas are located in the rigid housing, flexible coil assembly and between the two housings to detect NMR signals from each surface of the shoulder.
    Type: Application
    Filed: April 11, 2019
    Publication date: October 15, 2020
    Inventors: Kyle Johnson, Brian Brown, Venkat Goruganti, Michael Haase
  • Patent number: 10799144
    Abstract: A patient support assembly for use in a magnetic resonance image (MRI) scanner includes a first and a second patient support structure and a first and a second imaging coil. The patient support assembly provides support for multiple anatomical regions being imaged, improving patient comfort during the procedure. Access to the patient is improved by: providing a flexible coil that wraps around at least one of the anatomical regions being imaged, providing a support structure open to the anterior region of the anatomical region being imaged, and providing a support structure that may be opened and closed about the anatomical region being imaged. The patient support assembly also aligns the two imaging coils to minimize interference between coils during imaging.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: October 13, 2020
    Assignee: Neocoil, LLC
    Inventors: Robert D. Rohr, Christopher J. Salimes, Leslie A. Wagner, Venkat Goruganti, Brian Brown
  • Publication number: 20200299340
    Abstract: The present invention is directed to a fusion protein comprising a scaffold protein and a series of two or more epitopes, where the distinct epitopes are recognized by distinct antibodies, and where the series of epitopes forms a detectable protein tag. The present invention further relates to a nucleic acid molecule encoding a nucleic acid sequence encoding the fusion protein, as well as vectors comprising the nucleic acid molecule. Methods of tracking a cell and kits using such vectors are also disclosed.
    Type: Application
    Filed: August 24, 2018
    Publication date: September 24, 2020
    Inventors: Brian BROWN, Aleksandra WROBLEWSKA
  • Publication number: 20200171838
    Abstract: A method of inkjet printing includes the steps of: (i) delivering ink to a printhead manifold having a longitudinal ink channel, one or printhead chips mounted to a floor of the printhead manifold and in fluid communication with the longitudinal ink channel, and a plurality of sealed air cavities positioned over the longitudinal ink channel for dampening pressure fluctuations in the ink; (ii) printing from the printhead chips; and (iii) replenishing the air cavities with air.
    Type: Application
    Filed: February 6, 2020
    Publication date: June 4, 2020
    Inventors: Garry Jackson, Norman Berry, Michael Hudson, Brian Brown, Samuel Mallinson, Geordie McBain
  • Publication number: 20200172972
    Abstract: Modified nucleic acid adapters are provided that collectively provide a mixture of nucleotides at the 3? end of 5? adapters and at the 5? end of 3? adapters such that at least one adapter in each set has any given nucleotide at position 1, i.e., the nucleotide position available for ligation to a small RNA, and has any given nucleotide at position 2 adjacent to position 1 for use in overcoming bias during nucleic acid manipulation, such as small RNA characterization and/or profiling by, e.g., deep sequencing, along with methods for use of the modified adapters in small RNA characterization. The modified adapters have at least two mixed nucleotides at the adapter terminus to be ligated to a nucleic acid such as a small RNA.
    Type: Application
    Filed: February 7, 2020
    Publication date: June 4, 2020
    Inventors: Ravi Sachidanandam, Anitha Jayaprakash, Brian Brown
  • Patent number: 10589537
    Abstract: An inkjet printhead including: an elongate fluid manifold having a base defining a plurality of fluid outlets; and printhead chips attached to the base, each printhead chip receiving printing fluid from a plurality of the fluid outlets. All fluid outlets are laterally flared towards a side of a respective printhead chip.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: March 17, 2020
    Assignee: Memjet Technology Limited
    Inventors: Garry Jackson, Norman Berry, Michael Hudson, Brian Brown, Samuel Mallinson, Geordie McBain
  • Patent number: 10557169
    Abstract: Modified nucleic acid adapters are provided that collectively provide a mixture of nucleotides at the 3? end of 5? adapters and at the 5? end of 3? adapters such that at least one adapter in each set has any given nucleotide at position 1, i.e., the nucleotide position available for ligation to a small RNA, and has any given nucleotide at position 2 adjacent to position 1 for use in overcoming bias during nucleic acid manipulation, such as small RNA characterization and/or profiling by, e.g., deep sequencing, along with methods for use of the modified adapters in small RNA characterization. The modified adapters have at least two mixed nucleotides at the adapter terminus to be ligated to a nucleic acid such as a small RNA.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: February 11, 2020
    Assignee: Mount Sinai School of Medicine
    Inventors: Ravi Sachidanandam, Anitha Jayaprakash, Brian Brown
  • Publication number: 20200023925
    Abstract: The invention relates to an apparatus and related method for cleaning vessel hulls and other subsea structures at sea. In an embodiment, a hull cleaning system comprises a housing defining an interior void; a multifunction bar; a propulsion system; a power system; a positioning system; a water pump operatively connected to the power system; a high flow manifold operatively in fluid communication with the water pump; a hull cleaner; and a suction device configured to selectively adhere the hull cleaning system to a hull.
    Type: Application
    Filed: July 26, 2019
    Publication date: January 23, 2020
    Applicant: Oceaneering International, Inc.
    Inventors: Jeffery Neal Ledda, Bruce Brian Brown, George Kotula, Thomas Knight Tolman, Gary Wieboldt, Christopher Embree Wong
  • Publication number: 20190358214
    Abstract: The present invention features compositions and methods for the treatment of HCV infection. In one embodiment, the compositions of the invention comprise (1) Compound 1 or a pharmaceutically acceptable salt thereof, and (2) Compound 2a or a pharmaceutically acceptable salt thereof. In another embodiment, the compositions of the invention comprise (1) Compound 1 or a pharmaceutically acceptable salt thereof, and (2) a prodrug of Compound 2a (e.g., one of Compounds 2b-2k or Examples 3-1 to 3-10) or a pharmaceutically acceptable salt of said prodrug.
    Type: Application
    Filed: November 13, 2017
    Publication date: November 28, 2019
    Applicant: AbbVie Inc.
    Inventors: Brian Brown, Hui-Ju Chen, David DeGoey, Geoff Halvorsen, John Hartung, Howard R. Heyman, Nathan Ide, Dale Kempf, Allen C. Krueger, Tao Li, Tongmei Li, Steven R. Martinez, Christopher C. Marvin, John T. Randolph, Eric Voight, Rolf Wagner, Jaclyn Chau