Patents by Inventor Brian C. Kraemer

Brian C. Kraemer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210386709
    Abstract: Described herein are compositions and methods for treating Alzheimer's disease, a tauopathy disorder or dementia. The compositions include mammalian suppressor of taupathy 2 (MSUT2) inhibitors. The methods include steps for identifying candidate compositions capable of inhibiting RNA binding proteins to poly(A) RNA and detecting RNA polyadenylation of poly(A) RNA. The methods include reducing accumulation of phosphorylated and aggregated human tau.
    Type: Application
    Filed: May 13, 2021
    Publication date: December 16, 2021
    Inventors: JEREMY D. BAKER, Rikki L. Uhrich, Timothy J. Stovas, Aleen D. Saxton, Brian C. Kraemer
  • Patent number: 10606716
    Abstract: Power line disturbance hold up times are dynamically adjusted based on battery capacity of a plurality of batteries in a plurality of racks upon determining an amount of the power line disturbance one of the plurality of racks, having a fewest number of remaining batteries of the plurality of batteries with the battery capacity, is able to support.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: March 31, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mann Du, Ya-Huey Juan, Larry Juarez, Brian C. Kraemer, Ronald D. Martens, Su Qin, Todd C. Sorenson, Ji Qiu Xu
  • Publication number: 20180081772
    Abstract: Power line disturbance hold up times are dynamically adjusted based on battery capacity of a plurality of batteries in a plurality of racks upon determining an amount of the power line disturbance one of the plurality of racks, having a fewest number of remaining batteries of the plurality of batteries with the battery capacity, is able to support.
    Type: Application
    Filed: November 29, 2017
    Publication date: March 22, 2018
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mann DU, Ya-Huey JUAN, Larry JUAREZ, Brian C. KRAEMER, Ronald D. MARTENS, Su QIN, Todd C. SORENSON, Ji Qiu XU
  • Patent number: 9886356
    Abstract: Power line disturbance hold up times are dynamically adjusted based on battery capacity of a plurality of batteries in a plurality of racks by determining which one of the plurality of racks has a fewest number of remaining batteries of the plurality of batteries having the battery capacity. A determination of an amount of the power line disturbance the one of the plurality of racks, having the fewest number of remaining batteries of the plurality of batteries with the battery capacity, is able to support.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: February 6, 2018
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mann Du, Ya-Huey Juan, Larry Juarez, Brian C. Kraemer, Ronald D. Martens, Su Qin, Todd C. Sorenson, Ji Qiu Xu
  • Patent number: 9866444
    Abstract: Embodiments herein provide for a method of dynamically converting servers and a computer and storage readable medium configured to do the same. In the method a first server enters a server conversion while a second server performs one or more network services. A current physical hardware configuration and logical hardware configuration of a first server and a second server is verified. Possible conversions are calculated of one or more valid logical hardware configurations and one or more valid physical hardware configurations based on the current hardware configurations of the first server and the second server. A valid physical hardware configuration is selected for both servers from the calculated possible conversions. The physical hardware is updated for the conversion of the physical hardware configuration of the first server. The current logical configuration of the first server converts to a valid logical hardware configuration based on the calculated possible conversions.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: January 9, 2018
    Assignee: International Business Machines Corporation
    Inventors: Ya-Huey Juan, Brian C. Kraemer, Michael N. Nguyen, Jing Peng, Tracy N. Waller
  • Publication number: 20160246693
    Abstract: Power line disturbance hold up times are dynamically adjusted based on battery capacity of a plurality of batteries in a plurality of racks by determining which one of the plurality of racks has a fewest number of remaining batteries of the plurality of batteries having the battery capacity. A determination of an amount of the power line disturbance the one of the plurality of racks, having the fewest number of remaining batteries of the plurality of batteries with the battery capacity, is able to support.
    Type: Application
    Filed: May 5, 2016
    Publication date: August 25, 2016
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mann DU, Ya-Huey JUAN, Larry JUAREZ, Brian C. KRAEMER, Ronald D. MARTENS, Su QIN, Todd C. SORENSON, Ji Qiu XU
  • Publication number: 20160156525
    Abstract: Embodiments herein provide for a method of dynamically converting servers and a computer and storage readable medium configured to do the same. In the method a first server enters a server conversion while a second server performs one or more network services. A current physical hardware configuration and logical hardware configuration of a first server and a second server is verified. Possible conversions are calculated of one or more valid logical hardware configurations and one or more valid physical hardware configurations based on the current hardware configurations of the first server and the second server. A valid physical hardware configuration is selected for both servers from the calculated possible conversions. The physical hardware is updated for the conversion of the physical hardware configuration of the first server. The current logical configuration of the first server converts to a valid logical hardware configuration based on the calculated possible conversions.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 2, 2016
    Inventors: Ya-Huey Juan, Brian C. Kraemer, Michael N. Nguyen, Jing Peng, Tracy N. Waller
  • Patent number: 9348390
    Abstract: Power line disturbance hold up times are dynamically adjusted prior to the commencement of the power disturbance failover based on battery capacity of batteries in racks of the storage system as the batteries either fail, are repaired, or are added to the storage system having at least one uninterruptible power supply (UPS).
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: May 24, 2016
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mann Du, Ya-Huey Juan, Larry Juarez, Brian C. Kraemer, Ronald D. Martens, Su Qin, Todd C. Sorenson, Ji Qiu Xu
  • Patent number: 9306805
    Abstract: Embodiments herein provide for a method of dynamically converting servers and a computer and storage readable medium configured to do the same. In the method a first server enters a server conversion while a second server performs one or more network services. A current physical hardware configuration and logical hardware configuration of a first server and a second server is verified. Possible conversions are calculated of one or more valid logical hardware configurations and one or more valid physical hardware configurations based on the current hardware configurations of the first server and the second server. A valid physical hardware configuration is selected for both servers from the calculated possible conversions. The physical hardware is updated for the conversion of the physical hardware configuration of the first server. The current logical configuration of the first server converts to a valid logical hardware configuration based on the calculated possible conversions.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: April 5, 2016
    Assignee: International Business Machines Corporation
    Inventors: Ya-Huey Juan, Brian C. Kraemer, Michael N. Nguyen, Jing Peng, Tracy N. Waller
  • Publication number: 20150127784
    Abstract: Embodiments herein provide for a method of dynamically converting servers and a computer and storage readable medium configured to do the same. In the method a first server enters a server conversion while a second server performs one or more network services. A current physical hardware configuration and logical hardware configuration of a first server and a second server is verified. Possible conversions are calculated of one or more valid logical hardware configurations and one or more valid physical hardware configurations based on the current hardware configurations of the first server and the second server. A valid physical hardware configuration is selected for both servers from the calculated possible conversions. The physical hardware is updated for the conversion of the physical hardware configuration of the first server. The current logical configuration of the first server converts to a valid logical hardware configuration based on the calculated possible conversions.
    Type: Application
    Filed: November 7, 2013
    Publication date: May 7, 2015
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Ya-Huey Juan, Brian C. Kraemer, Michael N. Nguyen, Jing Peng, Tracy N. Waller
  • Publication number: 20140331070
    Abstract: Power line disturbance hold up times are dynamically adjusted prior to the commencement of the power disturbance failover based on battery capacity of batteries in racks of the storage system as the batteries either fail, are repaired, or are added to the storage system having at least one uninterruptible power supply (UPS).
    Type: Application
    Filed: May 3, 2013
    Publication date: November 6, 2014
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mann DU, Ya-Huey JUAN, Larry JUAREZ, Brian C. KRAEMER, Ronald D. MARTENS, Su QIN, Todd C. SORENSON, Ji Qiu XU
  • Patent number: 7533292
    Abstract: A RAID system employs a storage controller, a primary storage array having a plurality of primary storage units, and a spare storage pool having one or more spare storage units. A method of operating the storage controller in managing the primary storage array and the spare storage pool involves a testing by the storage controller of at least one repair service threshold representative of one or more operational conditions indicative of a necessity to repair at least one of the primary storage array and the spare storage unit, and a selective initiation by the storage controller of a repair service action for repairing one of the primary storage array and the spare storage unit based on the testing of the at least one repair service threshold.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: May 12, 2009
    Assignee: International Business Machines Corporation
    Inventors: Steven R. Van Gundy, Michael T. Benhase, Brian C. Kraemer, Richard A. Ripberger