Patents by Inventor Brian Cai

Brian Cai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL FORMULATIONS
    Publication number: 20240139109
    Abstract: The pharmacokinetic profile of the SGLT2 inhibitor bexagliflozin can be improved by formulating it as an extended release tablet. Compared with standard immediate-release dosage forms these tablets can permit a lower peak plasma concentration, Cmax, while maintaining plasma concentrations at therapeutic levels for a desired period. This can be used, for instance, to administer lower doses while still providing the same pharmacological effect.
    Type: Application
    Filed: November 3, 2023
    Publication date: May 2, 2024
    Inventors: Feng WANG, Ankit SHRIVASTAVA, Rina SHAH, Brian SEED, Vinay PATIL, Michael J. HADD, Fuxia DONG, Vipan DHALL, Chunfeng DAI, Joseph Ho-Lun CHAU, Qiuhua CAI
  • Method of detecting cleaved SNAP25 in tissue samples
    Patent number: 10527620
    Abstract: Methods and compositions for detecting BoNT/A enzymatic activity in tissues or a tissue sample are described herein. The invention encompasses antibodies that bind preferentially to BoNT/A cleaved SNAP25 and is able to preferentially detect BoNT/A cleaved SNAP25, as compared to intact (non-cleaved) SNAP25, in a tissue sample.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: January 7, 2020
    Assignee: Allergan, Inc.
    Inventors: Ron S. Broide, Brian Cai, Ester Fernandez-Salas, Joseph Francis, Catherine Rheaume
  • METHOD OF DETECTING CLEAVED SNAP25 IN TISSUE SAMPLES
    Publication number: 20190317095
    Abstract: Methods and compositions for detecting BoNT/A enzymatic activity in tissues or a tissue sample are described herein. The invention encompasses antibodies that bind preferentially to BoNT/A cleaved SNAP25 and is able to preferentially detect BoNT/A cleaved SNAP25, as compared to intact (non-cleaved) SNAP25, in a tissue sample.
    Type: Application
    Filed: June 14, 2019
    Publication date: October 17, 2019
    Inventors: Ron S. Broide, Brian Cai, Ester Fernandez-Salas, Joseph Francis, Catherine Rheaume
  • METHOD OF DETECTING CLEAVED SNAP25 IN TISSUE SAMPLES
    Publication number: 20160003824
    Abstract: Methods and compositions for detecting BoNT/A enzymatic activity in tissues or a tissue sample are described herein. The invention encompasses antibodies that bind preferentially to BoNT/A cleaved SNAP25 and is able to preferentially detect BoNT/A cleaved SNAP25, as compared to intact (non-cleaved) SNAP25, in a tissue sample.
    Type: Application
    Filed: July 7, 2015
    Publication date: January 7, 2016
    Inventors: Ron S. Broide, Brian Cai, Ester Fernandez-Salas, Joseph Francis, Catherine Rheaume