Patents by Inventor Brian Castle

Brian Castle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to identify and analyze genes having modified expression in stimulated T cells
    Publication number: 20060019303
    Abstract: A method of identifying genes involved in the stimulation of primary T cells comprising the steps of: a) contacting experimental cells with a stimulating agent; b) preparing RNA from said experimental cells at one or more stimulation phases; c) measuring the level of gene expression in the cells; d) comparing the levels of gene expression of said experimental cells to the level of gene expression in control cells that have not been exposed to an stimulation agent; e) identifying genes that are up regulated or down regulated in said experimental cells relative to said control cells.
    Type: Application
    Filed: July 22, 2005
    Publication date: January 26, 2006
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Brian Castle, Jianfei Yang, Xiang Li, Jun Li
  • Collateral data combined with other data to select web site
    Publication number: 20020062382
    Abstract: The present invention provides a system where collateral information stored in an image (or in some other data) is used together with other information such as information from a cookie on the machine used to access the collateral data, to direct a user to a particular web site. The site to which a user is directed is selected based both upon the collateral information in a web site, information from the computer that was used to read the collateral data, and information from a data base. The result is that user is directed to a web site that is more appropriate for the user at that particular time.
    Type: Application
    Filed: November 5, 2001
    Publication date: May 23, 2002
    Inventors: Geoffrey B. Rhoads, Christopher Oney, Phlipr Seder, William Hein, James Brian Castle
  • B cell culture system comprising high density membrane bound CD40 ligand
    Patent number: 6297052
    Abstract: The present invention provides methods of proliferating B cells as a means of obtaining large numbers of B cells. The present invention further provides methods of differentiating a proliferating B cell population to antibody producing cells.
    Type: Grant
    Filed: April 24, 1997
    Date of Patent: October 2, 2001
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Marilyn Kehry, Brian Castle
  • Methods for proliferating and differentiating B cells with high density membrane CD40 ligand
    Patent number: 5817516
    Abstract: The present invention provides methods of proliferating B cells as a means of obtaining large numbers of B cells. The present invention further provides methods of differentiating a proliferating B cell population to antibody producing cells.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: October 6, 1998
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Marilyn Kehry, Brian Castle