Patents by Inventor Brian Cathers

Brian Cathers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • UREA DERIVATIVES AS PYRUVATE KINASE ACTIVATORS
    Publication number: 20230278984
    Abstract: The subject matter described herein is directed to pyruvate kinase activating compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds and methods of administering the compounds for the treatment of diseases associated with PKR and/or PKM2, such as pyruvate kinase deficiency, sickle cell disease, and beta-thalassemia.
    Type: Application
    Filed: August 3, 2021
    Publication date: September 7, 2023
    Inventors: Lina Q. Setti, Brian Cathers, Zhe Li, Shahul Nilar, James Partridge, Chul Yu, Ming Yu, Manuel Zancanella