Abstract: The present invention provides tools and methods for the systematic analysis of genetic interactions, including higher order interactions. The present invention provides tools and methods for combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.

Abstract: Methods and compositions for producing induced pluripotent stem cell by introducing nucleic acids encoding one or more transcription factors including Obox6 into a target cell.

Abstract: The present invention relates to tissue and cell imaging utilizing genomic informatics and gene-expression profiling. Gene-expression profiles utilized in methods to obtain in situ imaging of cells and tissues provide complex molecular fingerprints regarding the relative state of a cell or tissue.

Abstract: The present invention provides tools and methods for the systematic analysis of genetic interactions, including higher order interactions. The present invention provides tools and methods for combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.

Abstract: The present invention relates to genomic informatics and gene-expression profiling. Gene-expression profiles provide complex molecular fingerprints regarding the relative state of a cell or tissue. Similarities in gene-expression profiles between organic states provide molecular taxonomies, classification, and diagnostics. Similarities in gene-expression profiles resulting from various external perturbations reveal functional similarities between these perturbagens, of value in pathway and mechanism-of-action elucidation. Similarities in gene-expression profiles between organic and induced states may identify clinically-effective therapies. Systems and methods herein provide for the measurement of relative gene abundances, including unbiased selection of and construction of probes and targets designed and methods for using known properties of sparsity of measurements to reach gene abundances.

Abstract: This tool would make automotive wheel lug nut tightening an exact science, insuring precision from one job to the next. Chances for human error are minimized; once the tool is correctly applied to the lug nuts, there is no need to rely on any particular expertise from the mechanic, as the tool takes over setting the wheel properly, and then applying the final correct torque in accord with manufacturer's specification.

Abstract: A method describes enriching a Call Detail Record (CDR) to identify traffic routing through network providers. The method comprises the steps of obtaining Operator Carrier Numbers (OCNs) assigned to network providers operating in a network; obtaining trunk group identifiers for identifying trunks configured to interconnect an Originating Provider's network including a Mobile Switching Center (MSC) with network providers; and identifying network providers configured to communicate through the trunk groups with the Originating Provider's network, including the MSC. The method also obtains a Called Party Number (CdPN) from the CDR; and associates the CdPN with an OCN of a network provider. The method also determines whether the OCN associated with the trunk group and the OCN of the CdPN are the same.

Abstract: A method includes receiving, at a processor, Call Detail Records (CDRs) from a Data Mediation System, in which each CDR includes a called party number (CdPN) associated with a first device, and a Cell Site ID associated with a location of a cell carrying a communication from a second device. Also included are: obtaining, from a first digital table, a first Major Trading Area (MTA) associated with the CdPN; obtaining, from a second digital table, a second MTA associated with the Cell Site ID; and concluding that the first and second devices are communicating in Local Traffic, if the first MTA is the same as the second MTA. The method may also conclude that the first and second devices are communicating in Long Distance Traffic, if the first MTA and second MTA are not the same.

Abstract: A method includes receiving, at a processor, Call Detail Records (CDRs) from a Data Mediation System, in which each CDR includes a called party number (CdPN) associated with a first device, and a Cell Site ID associated with a location of a cell carrying a communication from a second device. Also included are: obtaining, from a first digital table, a first Major Trading Area (MTA) associated with the CdPN; obtaining, from a second digital table, a second MTA associated with the Cell Site ID; and concluding that the first and second devices are communicating in Local Traffic, if the first MTA is the same as the second MTA. The method may also conclude that the first and second devices are communicating in Long Distance Traffic, if the first MTA and second MTA are not the same.

Abstract: A method describes enriching a Call Detail Record (CDR) to identify traffic routing through network providers. The method comprises the steps of obtaining Operator Carrier Numbers (OCNs) assigned to network providers operating in a network; obtaining trunk group identifiers for identifying trunks configured to interconnect an Originating Provider's network including a Mobile Switching Center (MSC) with network providers; and identifying network providers configured to communicate through the trunk groups with the Originating Provider's network, including the MSC. The method also obtains a Called Party Number (CdPN) from the CDR; and associates the CdPN with an OCN of a network provider. The method also determines whether the OCN associated with the trunk group and the OCN of the CdPN are the same.

Abstract: An interactive greeting card having a multi-panel greeting card body, a sound module and a molded track contained between two or more panels of the multi-panel greeting card body, and a moveable object which is attached to the molded track through an opening in one or more of the greeting card panels. The moveable object is operative to move from one end of the molded track to the opposite end of the molded track whereby playback of a pre-recorded digital audio file is initiated. The interactive greeting card may additionally contain a small motor which causes movement of a second moveable object and an object launcher which is operative to launch an object along the track and into the air. Other special effects may be included such as lights, additional sounds or movement, or any other special effects which can be incorporated into a greeting card.

Abstract: An interactive greeting card having a multi-panel greeting card body, a sound module and a molded track contained between two or more panels of the multi-panel greeting card body, and a moveable object which is attached to the molded track through an opening in one or more of the greeting card panels. The moveable object is operative to move from one end of the molded track to the opposite end of the molded track whereby playback of a pre-recorded digital audio file is initiated. The interactive greeting card may additionally contain a small motor which causes movement of a second moveable object and an object launcher which is operative to launch an object along the track and into the air. Other special effects may be included such as lights, additional sounds or movement, or any other special effects which can be incorporated into a greeting card.