Patents by Inventor Brian Curtis Turner

Brian Curtis Turner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONDITIONALLY IMMORTALIZED LONG-TERM STEM CELLS AND METHODS OF MAKING AND USING SUCH CELLS
    Publication number: 20160040129
    Abstract: Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of using such cells, and methods to identify compounds related to cell differentiation and development or to treat diseases, using such cells. A mouse model of acute myeloid leukemia (AML) and cells and methods related to such mouse model are also described.
    Type: Application
    Filed: October 2, 2015
    Publication date: February 11, 2016
    Inventors: John C. CAMBIER, Yosef REFAELI, Sara Ann JOHNSON, Brian Curtis Turner
  • Methods for preparing mature erythrocytes from conditionally immortalized hematopoietic stem cells
    Patent number: 9169462
    Abstract: Provided herein are methods for preparing differentiated cells, and the cells prepared by such methods.
    Type: Grant
    Filed: July 21, 2009
    Date of Patent: October 27, 2015
    Assignee: Taiga Biotechnologies, Inc.
    Inventors: Yosef Refaeli, Brian Curtis Turner
  • Conditionally immortalized long-term stem cells and methods of making and using such cells
    Patent number: 9150831
    Abstract: Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of using such cells, and methods to identify compounds related to cell differentiation and development or to treat diseases, using such cells. A mouse model of acute myeloid leukemia (AML) and cells and methods related to such mouse model are also described.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: October 6, 2015
    Assignees: The Regents of the University of Colorado, National Jewish Health
    Inventors: John C. Cambier, Yosef Refaeli, Sara Ann Johnson, Brian Curtis Turner
  • CONDITIONALLY IMMORTALIZED LONG-TERM STEM CELLS AND METHODS OF MAKING AND USING SUCH CELLS
    Publication number: 20150240205
    Abstract: Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of using such cells, and methods to identify compounds related to cell differentiation and development or to treat diseases, using such cells. A mouse model of acute myeloid leukemia (AML) and cells and methods related to such mouse model are also described.
    Type: Application
    Filed: October 8, 2014
    Publication date: August 27, 2015
    Inventors: John C. CAMBIER, Yosef REFAELI, Sara Ann JOHNSON, Brian Curtis Turner
  • Antibodies and processes for preparing the same
    Patent number: 8986702
    Abstract: Provided herein are various processes for the improved production of antibody producing organisms, antibody producing tissues, antibody producing cells and antibodies. In certain embodiments, provided herein are methods for rapidly producing antibody producing organisms, tissues, cells and antibodies derived from humans, organisms, plants or cells that are genetically altered to over-express certain proteins.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: March 24, 2015
    Assignee: Taiga Biotechnologies, Inc.
    Inventors: Yosef Refaeli, Brian Curtis Turner
  • MODULATORS OF MYC, METHODS OF USING THE SAME, AND METHODS OF IDENTIFYING AGENTS THAT MODULATE MYC
    Publication number: 20140356392
    Abstract: Disclosed herein are methods of modulation of the viability of a cell. Further disclosed herein are methods of modulating an immune response. Further disclosed herein are methods of identifying agents capable of modulation of the viability of a cell or an immune response. Further disclosed herein are agents and compositions capable of modulation of the viability of a cell or an immune response.
    Type: Application
    Filed: August 15, 2014
    Publication date: December 4, 2014
    Applicant: TAIGA BIOTECHNOLOGIES, INC.
    Inventors: Yosef REFAELI, Brian Curtis Turner
  • Conditionally immortalized long-term hematopoietic stem cells and methods of making and using such cells
    Patent number: 8883507
    Abstract: Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of using such cells, and methods to identify compounds related to cell differentiation and development or to treat diseases, using such cells. A mouse model of acute myeloid leukemia (AML) and cells and methods related to such mouse model are also described.
    Type: Grant
    Filed: October 18, 2006
    Date of Patent: November 11, 2014
    Assignees: The Regents of the University of Colorado, National Jewish Health
    Inventors: John C. Cambier, Yosef Refaeli, Sara Ann Johnson, Brian Curtis Turner
  • EXPANSION OF ADULT STEM CELLS IN VITRO
    Publication number: 20140273212
    Abstract: Disclosed are methods for manipulating and expanding stem cell populations, including adult stem cells, the cells produced by such methods, and various protein constructs related thereto.
    Type: Application
    Filed: March 12, 2013
    Publication date: September 18, 2014
    Applicant: Taiga Biotechnologies, Inc.
    Inventors: BRIAN CURTIS TURNER, YOSEF REFAELI, GREGORY BIRD
  • Modulators of MYC, methods of using the same, and methods of identifying agents that modulate MYC
    Patent number: 8828723
    Abstract: Disclosed herein are methods of modulation of the viability of a cell. Further disclosed herein are methods of modulating an immune response. Further disclosed herein are methods of identifying agents capable of modulation of the viability of a cell or an immune response. Further disclosed herein are agents and compositions capable of modulation of the viability of a cell or an immune response.
    Type: Grant
    Filed: February 26, 2013
    Date of Patent: September 9, 2014
    Assignee: Taiga Biotechnologies, Inc.
    Inventors: Yosef Refaeli, Brian Curtis Turner
  • Modulators of MYC, methods of using the same, and methods of identifying agents that modulate MYC
    Patent number: 8784825
    Abstract: Disclosed herein are methods of modulation of the viability of a cell. Further disclosed herein are methods of modulating an immune response. Further disclosed herein are methods of identifying agents capable of modulation of the viability of a cell or an immune response. Further disclosed herein are agents and compositions capable of modulation of the viability of a cell or an immune response.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: July 22, 2014
    Assignee: Taiga Biotechnologies, Inc.
    Inventors: Yosef Refaeli, Brian Curtis Turner
  • Methods for generation of antibodies
    Patent number: 8551968
    Abstract: This invention generally relates to methods for the production of antibody producing cells and antibodies in protooncogene expressing animals. The invention also relates to methods for the efficient production of antibodies specific for antigens that are normally subject to immunological constraints such as self tolerance. The invention further relates to the production of antibody producing cells and antibodies without the need for the conventional fusing of antibody producing B cells with a myeloma fusion partner.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: October 8, 2013
    Assignee: National Jewish Health
    Inventors: Yosef Refaeli, Brian Curtis Turner
  • ANTIBODIES AND PROCESSES FOR PREPARING THE SAME
    Publication number: 20110263820
    Abstract: Provided herein are various processes for the improved production of antibody producing organisms, antibody producing tissues, antibody producing cells and antibodies. In certain embodiments, provided herein are methods for rapidly producing antibody producing organisms, tissues, cells and antibodies derived from humans, organisms, plants or cells that are genetically altered to over-express certain proteins.
    Type: Application
    Filed: December 7, 2010
    Publication date: October 27, 2011
    Applicant: Taiga Biotechnologies, Inc.
    Inventors: Yosef Refaeli, Brian Curtis Turner
  • COMPOUNDS FOR TREATING ABNORMAL CELLULAR PROLIFERATION
    Publication number: 20110218210
    Abstract: Provided herein are compounds, compositions and methods for treating disorders mediated by abnormal cellular proliferation and processes for identifying such compounds.
    Type: Application
    Filed: November 3, 2008
    Publication date: September 8, 2011
    Applicant: Taiga Biotechnologies
    Inventors: Yosef Refaeli, Brian Curtis Turner
  • CONDITIONALLY IMMORTALIZED LONG-TERM STEM CELLS AND METHODS OF MAKING AND USING SUCH CELLS
    Publication number: 20100297763
    Abstract: Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of using such cells, and methods to identify compounds related to cell differentiation and development or to treat diseases, using such cells. A mouse model of acute myeloid leukemia (AML) and cells and methods related to such mouse model are also described.
    Type: Application
    Filed: February 5, 2010
    Publication date: November 25, 2010
    Applicant: TAIGA BIOTECHNOLOGIES, INC.
    Inventors: John C. Cambier, Yosef Refaeli, Sara Ann Johnson, Brian Curtis Turner
  • Method for Generation of Antibodies
    Publication number: 20100279351
    Abstract: This invention generally relates to methods for the production of antibody producing cells and antibodies in protooncogene expressing animals. The invention also relates to methods for the efficient production of antibodies specific for antigens that are normally subject to immunological constraints such as self tolerance. The invention further relates to the production of antibody producing cells and antibodies without the need for the conventional fusing of antibody producing B cells with a myeloma fusion partner.
    Type: Application
    Filed: March 13, 2008
    Publication date: November 4, 2010
    Applicant: NATIONAL JEWISH MEDICAL AND RESEARCH CENTER
    Inventors: Yosef Refaeli, Brian Curtis Turner
  • MODULATORS OF MYC, METHODS OF USING THE SAME, AND METHODS OF INDENTIFIYING AGENTS THAT MODULATE MYC
    Publication number: 20100055129
    Abstract: Disclosed herein are methods of modulation of the viability of a cell. Further disclosed herein are methods of modulating an immune response. Further disclosed herein are methods of identifying agents capable of modulation of the viability of a cell or an immune response. Further disclosed herein are agents and compositions capable of modulation of the viability of a cell or an immune response.
    Type: Application
    Filed: August 28, 2009
    Publication date: March 4, 2010
    Applicant: TAIGA BIOTECHNOLOGIES, INC.
    Inventors: Yosef Refaeli, Brian Curtis Turner
  • DIFFERENTIATED ANUCLEATED CELLS AND METHOD FOR PREPARING THE SAME
    Publication number: 20100047217
    Abstract: Provided herein are methods for preparing differentiated cells, and the cells prepared by such methods.
    Type: Application
    Filed: July 21, 2009
    Publication date: February 25, 2010
    Applicant: TAIGA BIOTECHNOLOGIES, INC.
    Inventors: Yosef REFAELI, Brian Curtis TURNER
  • ANTIBODIES AND PROCESSES FOR PREPARING THE SAME
    Publication number: 20090291094
    Abstract: Provided herein are various processes for the improved production of antibody producing organisms, antibody producing tissues, antibody producing cells and antibodies. In certain embodiments, provided herein are methods for rapidly producing antibody producing organisms, tissues, cells and antibodies derived from humans, organisms, plants or cells that are genetically altered to over-express certain proteins.
    Type: Application
    Filed: May 18, 2009
    Publication date: November 26, 2009
    Applicant: TAIGA BIOTECHNOLOGIES, INC.
    Inventors: Yosef Refaeli, Brian Curtis Turner