Abstract: Catheter blood pumps that include an expandable conduit coupled to at least one hub shaped to promote smooth blood flow. In some examples, the at least one hub includes a body with radially extending arms that are coupled to struts of the conduit. The hub may include channels having curved surfaces for promoting non-turbulent fluid flow around a distal opening and/or a proximal opening of the conduit. The arms may have ridge regions that extend axially along the body of the hub to define at least a portion of the channels.

Abstract: Catheter blood pump that include an expandable pump portion extending distally from an elongate shaft. The pump portions include an expandable impeller housing including an expandable blood conduit that defines a blood lumen between an inflow and an outflow. The pump portions include one or more expandable impellers disposed at least partially within the blood lumen.

Abstract: Intravascular blood pumps and methods of use. The blood pump include a pump portion that includes a collapsible blood conduit defining a blood flow lumen between an inflow and an outflow. The pump portion includes a distal collapsible impeller axially spaced from a proximal collapsible impeller, at least a portion of each of the distal and proximal collapsible impellers disposed between the inflow and the outflow.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

Abstract: Catheter blood pumps that include an expandable pump portion, which include an expandable impeller housing. The housings include an expandable blood conduit that defines a blood lumen, and one or more pluralities of expandable struts extending axially from an end region of the expandable blood conduit. At least one of the pluralities of struts are non-unitary with a blood conduit at the end region.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include an collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers. The collapsible scaffold and/or an elongate member extending proximally from the pump portion may include portions of differing radial stiffness or flexibility.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers. The collapsible scaffold may include portions of differing radial stiffness based on location of the one or more impellers therein.

Abstract: Catheter blood pump that include an expandable pump portion extending distally from an elongate shaft. The pump portions include an expandable impeller housing including an expandable blood conduit that defines a blood lumen between an inflow and an outflow. The pump portions include one or more expandable impellers disposed at least partially within the blood lumen.

Abstract: Catheter blood pumps that include a sensor system. The pumps may include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pumps may also include one or more impellers. One or more sensors may be arranged with respect to inflow and outflow regions of the blood lumen, the scaffold and/or the impellers.

Abstract: Catheter blood pumps that include a collapsible blood conduit, a collapsible scaffold portion, and a bend formed in the collapsible scaffold. The collapsible blood conduit defines a blood lumen. The collapsible scaffold is adapted to provide radial support to the blood conduit. The blood pump also includes one or more impellers.

Abstract: Cardiac tissue ablation catheters including an inflatable and flexible toroidal or spherically shaped balloon disposed at a distal region of an elongate member, a flexible circuit carried by an outer surface of the balloon, the flexible circuit including, a plurality of flexible branches conforming to the radially outer surface of the balloon, each of the plurality of flexible branches including a substrate, a conductive trace carried by the substrate, and an ablation electrode carried by the substrate, the ablation electrode in electrical communication with the conductive trace, and an elongate shaft comprising a guidewire lumen extending in the elongate member and extending from a proximal region of the inflatable balloon to distal region of the inflatable balloon and being disposed within the inflatable balloon, wherein a distal region of the elongate shaft is secured directly or indirectly to the distal region of the inflatable balloon.

Abstract: Catheter blood pumps that include an expandable pump portion, which include an expandable impeller housing. The housings include an expandable blood conduit that defines a blood lumen, and one or more pluralities of expandable struts extending axially from an end region of the expandable blood conduit. At least one of the pluralities of struts are non-unitary with a blood conduit at the end region.

Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

Abstract: Catheter blood pumps that include an expandable pump portion, which include an expandable impeller housing. The housings include an expandable blood conduit that defines a blood lumen, and one or more pluralities of expandable struts extending axially from an end region of the expandable blood conduit. At least one of the pluralities of struts are non-unitary with a blood conduit at the end region.

Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include an collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.