Abstract: A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images.

Abstract: A device includes: housing having top surface, bottom surface, and at least one side surface connected between top surface and bottom surface; a load cell positioned within housing; flexible section positioned within at least one of bottom surface or top surface of housing; rigid section positioned within flexible section, rigid section having opening surrounded by rigid material; rigid support having first end, second end, and center section; wherein first end of rigid support is positioned within housing and coupled to load cell; and wherein center section of rigid support passes through opening in rigid section positioned within flexible section, wherein center section of rigid support contacts rigid material of rigid section surrounding opening, wherein second end of rigid support is outside of housing.

Abstract: A compound includes a polysaccharide moiety and one or more chelating agents. The one or more chelating agents are covalently bonded to the polysaccharide moiety. The polysaccharide moiety can include a glycosaminoglycan moiety, such as a hyaluronic acid polymer or a sulfated glycosaminoglycan moiety. The compound can be used to treat or prevent a disease or disorder in a patient with a metal implant. The compound reduces a concentration of metal particulates or metal ions in the subject.

Abstract: The present invention provides certain chemical compounds or materials having adhesive properties or functionality that act as adhesives or sealants in a variety of applications. In particular, the invention, including its various embodiments, relates to certain functional graphenic materials having an attached adhesive moiety that provides adhesive properties or functionality to the resulting compound and that can be used as an adhesive or sealant in a variety of applications, such as in-situ repair of a leak or defect in a tube carrying a fluid, such as a condenser tube in a power plant.

Abstract: A method for functionalizing graphene oxide includes reacting graphene oxide with a phosphite compound and a metal salt in the presence of a Lewis acid to produce phosphate functionalized graphene oxide including ions of the metal. An apparatus includes a bone scaffold construct formed of phosphate functionalized graphene oxide including metal ions. A bone scaffold construct includes a graphene oxide material formed in the shape of the bone scaffold construct, the graphene oxide material including graphene oxide, phosphate moieties covalently bound to the graphene oxide, and metal counter ions chemically associated with the phosphate moieties. A method for treating a bone defect includes administering a therapeutically effective amount of phosphate functionalized graphene oxide including metal ions.

Abstract: A compound includes a polysaccharide moiety and one or more chelating agents. The one or more chelating agents are covalently bonded to the polysaccharide moiety. The polysaccharide moiety can include a glycosaminoglycan moiety, such as a hyaluronic acid polymer or a sulfated glycosaminoglycan moiety. The compound can be used to treat or prevent a disease or disorder in a patient with a metal implant. The compound reduces a concentration of metal particulates or metal ions in the subject.

Abstract: A substance measurement device includes: a container portion configured to receive a substance; a sensing device configured to measure a property of the substance related to at least one of a flow rate of the substance into the container portion, a level of the substance within the container portion, and a volume of the substance within the container portion; and at least one shield positioned within the container portion and configured to provide at least one of: a mechanical buffer between the substance entering the container portion and the sensing device; and an electrical shield between the substance entering the container portion and the sensing device.

Abstract: A substance measurement device includes: a container portion configured to receive a substance; a sensing device configured to measure a property of the substance related to at least one of a flow rate of the substance into the container portion, a level of the substance within the container portion, and a volume of the substance within the container portion; and at least one shield positioned within the container portion and configured to provide at least one of: a mechanical buffer between the substance entering the container portion and the sensing device; and an electrical shield between the substance entering the container portion and the sensing device.

Abstract: A housing of a pump apparatus includes an undivided cavity, an inlet valve through which liquid can enter the cavity, and an outlet valve through which the liquid can exit the cavity. A primary piston is configured to reciprocate in the cavity to draw the liquid into the cavity through the inlet valve during an intake stroke of the piston and discharge the liquid out of the cavity through the outlet valve during a delivery stroke. A reservoir structure is configured to add, to the total volume of the cavity, an extra volume that is a smooth positive function of liquid pressure in the cavity.

Abstract: A method of matching a vehicle with a vacant parking space in a parking facility having numerous parking spaces. The method includes storing identifying characteristics of each of the parking spaces in a database. To request a parking space, a garage customer inputs data concerning his or her preferences for parking. The inventive method then determines which of the plurality of parking spaces are vacant, matches the data inputted by the user with the data identifying characteristics of each of the parking spaces determined to be vacant, and determines which of the parking spaces determined to be vacant most closely matches the data inputted by the user. The closest parking space is reserved for parking by the user.

Abstract: A railroad vital relay control circuit has a first input for receiving a reference alternating current signal of a selected frequency and a second input for receiving a track alternating current signal having the selected frequency of the reference signal and a predetermined phase and magnitude relationship therewith. A magnetic core provides a logical AND function and has two input arms and an intermediate output arm. There is a winding on each of the input arms and a winding on the output arm. There are frequency tuned voltage limiting circuit elements connecting the first input and a first one of the magnetic core input windings and the second input and the second input winding of the magnetic core. The magnetic core has an output winding on the intermediate arm which is connected to a vital relay. The input windings on the magnetic core are connected to produce flux in the same direction in the output arm.