Patents by Inventor Brian D. O'Connor

Brian D. O'Connor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12228574
    Abstract: Systems, media, compositions, methods, and kits disclosed herein relate to a panel of protein biomarkers for the early detection of colon cell proliferative disorders, including colorectal cancer. The presence or levels of the proteins in a biological sample for the protein panels described herein may be used for classifier generation, and as inputs in machine learning models useful to classify subjects in a population for the detection of colon cell proliferative disorders.
    Type: Grant
    Filed: February 1, 2023
    Date of Patent: February 18, 2025
    Assignee: Freenome Holdings, Inc.
    Inventors: Hayley Warsinske, Adam Drake, Krishnan Kanna Palaniappan, Brian D. O'Donovan, John Hawkins
  • Patent number: 11717707
    Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: August 8, 2023
    Assignee: Guided Therapy Systems, LLC
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Publication number: 20230243830
    Abstract: Systems, media, compositions, methods, and kits disclosed herein relate to a panel of autoantibody biomarkers for the early detection of colon cell proliferative disorders, including colorectal cancer. The presence or levels of the autoantibodies in a biological sample for the autoantibody panels described herein may be used for classifier generation, and as inputs in machine learning models useful to classify subjects in a population for the detection of colon cell proliferative disorders.
    Type: Application
    Filed: February 1, 2023
    Publication date: August 3, 2023
    Inventors: Brian D. O'DONOVAN, Shivani MAHAJAN
  • Publication number: 20230176058
    Abstract: Systems, media, compositions, methods, and kits disclosed herein relate to a panel of protein biomarkers for the early detection of colon cell proliferative disorders, including colorectal cancer. The presence or levels of the proteins in a biological sample for the protein panels described herein may be used for classifier generation, and as inputs in machine learning models useful to classify subjects in a population for the detection of colon cell proliferative disorders.
    Type: Application
    Filed: February 1, 2023
    Publication date: June 8, 2023
    Inventors: Hayley WARSINSKE, Adam DRAKE, Krishnan Kanna PALANIAPPAN, Brian D. O'DONOVAN, John HAWKINS
  • Patent number: 11338156
    Abstract: Systems and methods for noninvasive tissue tightening are disclosed. Thermal treatment of tissues such as superficial muscular aponeurosis system (SMAS) tissue, muscle, adipose tissue, dermal tissue, and combinations thereof are described. In one aspect, a system is configured for treating tissue through delivery of ultrasound energy at a depth, distribution, temperature, and energy level to achieve a desired cosmetic effect.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: May 24, 2022
    Assignee: Guided Therapy Systems, LLC
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Publication number: 20220105364
    Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
    Type: Application
    Filed: December 17, 2021
    Publication date: April 7, 2022
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Patent number: 11235180
    Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: February 1, 2022
    Assignee: Guided Therapy Systems, LLC
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Publication number: 20210205637
    Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
    Type: Application
    Filed: March 23, 2021
    Publication date: July 8, 2021
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Patent number: 10960236
    Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: March 30, 2021
    Assignee: Guided Therapy Systems, LLC
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Patent number: 10794889
    Abstract: Imaging techniques are provided to determine the presence of trace chemicals corresponding to various materials of interest. In one example, a method includes receiving a test sample and capturing a plurality of infrared images of the test sample. Each infrared image corresponds to a different range of infrared radiation wavelengths. The method also includes determining a spectral profile of the test sample using the infrared images, comparing the determined spectral profile to a known spectral profile of a material of interest, and determining whether the material is present in the test sample based on the comparing. Additional methods and related devices are also provided.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: October 6, 2020
    Assignee: FLIR DETECTION, INC.
    Inventors: Robert K. Shelton, Brian D. O'Dell, Shiou-Jyh Ja
  • Publication number: 20200094083
    Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
    Type: Application
    Filed: November 27, 2019
    Publication date: March 26, 2020
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Patent number: 10525288
    Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: January 7, 2020
    Assignee: Guided Therapy Systems, LLC
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Publication number: 20190366128
    Abstract: Systems and methods for noninvasive tissue tightening are disclosed. Thermal treatment of tissues such as superficial muscular aponeurosis system (SMAS) tissue, muscle, adipose tissue, dermal tissue, and combinations thereof are described. In one aspect, a system is configured for treating tissue through delivery of ultrasound energy at a depth, distribution, temperature, and energy level to achieve a desired cosmetic effect.
    Type: Application
    Filed: August 16, 2019
    Publication date: December 5, 2019
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Patent number: 10067071
    Abstract: Techniques are disclosed for systems and methods to provide reliable analyte spatial detection systems. An analyte spatial detection system includes an imaging module, a visible light projector, associated processing and control electronics, and, optionally, orientation and/or position sensors integrated with the imaging module and/or the visible light projector. The imaging module includes sensor elements configured to detect electromagnetic radiation in one or more selected spectrums, such as infrared, visible light, and/or other spectrums. The visible light projector includes one or more types of projectors configured project visible light within a spatial volume monitored by the imaging module. The system may be partially or completely portable and/or fixed in place. The visible light projector is used to indicate presence of a detected analyte on a surface near or adjoining the spatial position of the detected analyte.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: September 4, 2018
    Assignee: FLIR Systems, Inc.
    Inventors: Brian D. O'Dell, Robert K. Shelton, Vu L. Nguyen
  • Publication number: 20180236273
    Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 23, 2018
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Patent number: 9974982
    Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: May 22, 2018
    Assignee: Guided Therapy Systems, LLC
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor
  • Patent number: 9973692
    Abstract: In one embodiment, a method for displaying a panoramic view image includes transmitting video data from a plurality of sensors to a data processor and using the processor to stitch the video data from respective ones of the sensors into a single panoramic image. A focus view of the image is defined and the panoramic image is scrolled such that the focus view is centered in the display. A high resolution camera is aimed along a line corresponding to a center of the focus view of the image and an image produced by the camera is stitched into the panoramic image. A mapping function is applied to the image data to compress the data and thereby reduce at least the horizontal resolution of the image in regions adjacent to the side edges thereof.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: May 15, 2018
    Assignee: FLIR SYSTEMS, INC.
    Inventors: Matthew Joseph Szabo, Phillip Vickery, Brian D. O'Dell, Andrew C. Teich, Jeffrey D. Frank
  • Publication number: 20180003689
    Abstract: Imaging techniques are provided to determine the presence of trace chemicals corresponding to various materials of interest. In one example, a method includes receiving a test sample and capturing a plurality of infrared images of the test sample. Each infrared image corresponds to a different range of infrared radiation wavelengths. The method also includes determining a spectral profile of the test sample using the infrared images, comparing the determined spectral profile to a known spectral profile of a material of interest, and determining whether the material is present in the test sample based on the comparing. Additional methods and related devices are also provided.
    Type: Application
    Filed: June 29, 2017
    Publication date: January 4, 2018
    Inventors: Robert K. Shelton, Brian D. O'Dell, Shiou-Jyh Ja
  • Publication number: 20170292917
    Abstract: Techniques are disclosed for systems and methods to provide reliable analyte spatial detection systems. An analyte spatial detection system includes an imaging module, a visible light projector, associated processing and control electronics, and, optionally, orientation and/or position sensors integrated with the imaging module and/or the visible light projector. The imaging module includes sensor elements configured to detect electromagnetic radiation in one or more selected spectrums, such as infrared, visible light, and/or other spectrums. The visible light projector includes one or more types of projectors configured project visible light within a spatial volume monitored by the imaging module. The system may be partially or completely portable and/or fixed in place. The visible light projector is used to indicate presence of a detected analyte on a surface near or adjoining the spatial position of the detected analyte.
    Type: Application
    Filed: April 5, 2017
    Publication date: October 12, 2017
    Inventors: Brian D. O'Dell, Robert K. Shelton, Vu L. Nguyen
  • Publication number: 20160228729
    Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
    Type: Application
    Filed: April 13, 2016
    Publication date: August 11, 2016
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin, Brian D. O'Connor