Abstract: A device for delivery of agent to a biological barrier may comprise a petal bearing main body having a set of guides each having an upstream and downstream portion. The device may further comprise a reservoir including at least one delivery sharp. The device may further comprise a plunger having a set of plunger protrusions each disposed in a respective guide. The device may further comprise a first bias member urging the plunger toward a position in which the protrusions are at an end of the downstream portions. The device may further comprise a trigger body with a first and second set of barriers. The trigger body may be displaceable between a position in which the second barriers are stowed and the first barriers obstruct displacement of the protrusions and another position in which the first barriers are stowed and the second barriers obstruct travel of the protrusions.

Abstract: A surgical instrument includes an end effector having a clamp arm pivotable relative to an ultrasonic blade, an articulation section configured to deflect the end effector, an acoustic waveguide having a distal portion extending along an axis, a clamp arm closure assembly comprising a body configured to actuate in order to drive the pivoting of the clamp arm, and a clamp arm clocking assembly. The clamp arm clocking assembly is capable of driving rotation of the clamp arm about the axis relative to the ultrasonic blade between a first clocked position and a second clocked position. The clamp arm clocking assembly includes a rotating body pivotally coupled with the clamp arm, a translating drive extending through the articulation section, and a rotation driver assembly. The rotation driver is in communication with the translating driver to convert translational motion of the translating driver into rotational motion of the rotating body.

Abstract: A therapeutic electrode component includes a base plate having a first side and a second side having a conductive surface. A repository having an internal volume to releasably retain a conductive fluid is disposed on the first side of the base plate. A rupturable membrane is disposed between the internal volume of the repository and the conductive surface of the base plate. A coupling is disposed on the base plate that is configured to detachably engage a gas charge, whereby the gas charge is detachable from the coupling without causing destruction of the gas charge, to provide a hermetic seal with an outlet of the gas charge, and to provide fluid communication between the internal volume of the repository and the outlet of gas charge when the gas charge is engaged by the coupling. A retainer is configured to detachably secure the gas charge to the base plate.

Abstract: An embodiment enables a first machine to receive an asynchronous data update from a second machine, the asynchronous data update comprising a first stream of identifiers and a second stream of data, wherein the first stream of identifiers comprises a first identifier corresponding to a first data segment in the second stream of data. An embodiment analyzes, as a part of the asynchronous data update, the first stream of identifiers. An embodiment determines at a first time, responsive to the analyzing, that the first data segment corresponding to the first identifier has not arrived at the first machine by the first time. An embodiment updates, responsive to the determining at the first time, a record at the first machine with the first identifier. An embodiment updates the record at a second time, responsive to receiving the first data segment at the first machine at the second time.

Abstract: Techniques and apparatus for extending a range of a ranging procedure performed using ultra-wide band (UWB) are described. An example technique includes receiving, by a first network entity, control information for a ranging procedure via a non-ultra-wide band (non-UWB) communication protocol. The ranging procedure is performed by the first network entity with a second network entity based on the control information and via an ultra-wide band (UWB) communication protocol.

Abstract: A resonant beam accelerometer employing a pair of double ended tuning forks and a proof mass having meso-scale mass as it is formed in the handle layer of a SOI wafer and a method of fabricating same is disclosed. The resonant frequencies of the pair of double ended tuning forks change in opposite directions when an externally applied acceleration is in a direction parallel to the pair of double ended tuning forks. Due to the proof mass having meso-scale mass, the resonant beam accelerometer is very sensitive. By employing a lid and a stator cap, the active portions of the resonant beam accelerometer may be sealed in a vacuum to further increase sensitivity.

Abstract: A staple cartridge assembly capable of coupling with a cartridge channel of a surgical stapler. The staple cartridge includes a staple cartridge body, a swing gate pivotably coupled with the staple cartridge body, and a bridge member extending across the central slot and located proximally relative to the swing gate. The staple cartridge body defines a central slot dimensioned to slidably receive a firing beam of the surgical stapler. The staple cartridge body includes a proximal end, a distal end, and a staple deck extending between the proximal end and the distal end. The staple deck defines staple openings. The swing gate can pivot between a first position and a second position. The swing gate extends across the central slot in the first position, while the swing gate extends alongside the central slot in the second position. The bridge member defines a closed proximal end of the central slot.

Abstract: Disclosed are systems, methods, and apparatuses for automatically and optically determining structural integrity and catch weight information for a pallet. The apparatus can include: a conveyor belt to route a pallet having cases in a facility once the pallet is ingested into the facility, a turntable to receive the pallet from the conveyor belt and rotate the pallet, at least one imaging device proximate the turntable to capture optical data of the pallet, a partial enclosure to enclose the turntable, the at least one imaging device, and at least a portion of the conveyor belt, and an edge computing device in network communication with the at least one imaging device. The edge computing device can: receive the optical data from the at least one imaging device, process the optical data to determine structural integrity and catch weight information for the pallet, and determine routing or storage information for the pallet.

Abstract: A system including a prosthesis assembly for a constrained knee including a tibial baseplate, a mobile bearing, and a fixed bearing. The tibial baseplate can include a distal surface and a proximal surface that can be configured to receive a hinge post. The mobile bearing can be configured to couple with the tibial baseplate and to rotate about at least a first axis approximated by a centerline of the hinge post. The rotation about at least the first axis can be limited by at least the first engagement feature. The fixed bearing can be configured to be coupled to the tibial baseplate. The fixed bearing can be restrained from rotating about the first axis by at least the first engagement feature of the tibial baseplate. The tibial baseplate can be configured to be assembled with either the mobile bearing or the fixed bearing.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

Abstract: Applicants have developed an amplification system and methodology for IHC and ISH staining that utilizes “click chemistry” to covalently bind reporter molecules to tissue.

Abstract: A composite material includes a plurality of metallic particles formed through modulation-assisted machining. The composite includes a thermoplastic polymer matrix which binds the plurality of metallic particles.

Abstract: A system for priming an infusion pump is disclosed. The system includes a priming cap including a septum and configured to matably connect with a male part comprising a needle and attached to a length of tubing for fluid, wherein when matably connected with the male part, the priming cap occludes the tubing.

Abstract: The subject technology provides for concurrent streaming of media content to multiple media devices. A host device may receive, from a first accessory device, a first request for first media content, the first request corresponding to a first voice input, and receive, from a second accessory device, a second request for second media content, the second request corresponding to a second voice input to the second accessory device. The host device may store a first context record including identification information for the first accessory device and the first media content, and store, while storing the first context record, a second context record including identification information for the second accessory device and the second media content. The host device may stream the first media content to the first accessory device, and stream, to second accessory device and concurrently with the streaming of the first media content, the second media content.

Abstract: Systems, media, compositions, methods, and kits disclosed herein relate to a panel of autoantibody biomarkers for the early detection of colon cell proliferative disorders, including colorectal cancer. The presence or levels of the autoantibodies in a biological sample for the autoantibody panels described herein may be used for classifier generation, and as inputs in machine learning models useful to classify subjects in a population for the detection of colon cell proliferative disorders.

Abstract: Technologies and implementations for a wearable healthcare system including an information management module (IMM). The IMM may be configured to detect proximity of a healthcare device. The IMM may be configured to determine a type of the detected healthcare device. Once the type of healthcare device is determined, the IMM may be configured to communicate information regarding a medical device, where the communicated information may be adapted to correspond to the determined type of healthcare device.

Abstract: An apparatus includes a shaft assembly, an ultrasonic blade, and a clamp assembly. The shaft assembly includes an acoustic waveguide operable to transmit ultrasonic vibrations to the blade. The clamp assembly includes a clamp arm pivotable toward and away from the blade about a pivot axis, to clamp tissue between the clamp arm and the blade. A rotation feature may provide rotation of the blade relative to the clamp arm about the longitudinal axis of the waveguide. Alternatively, the rotation feature may provide rotation of the clamp arm relative to the blade about the longitudinal axis. The rotation feature may be driven based on pivotal positioning of the clamp arm relative to the blade about the pivot axis. The rotation feature may selectively lock and unlock the angular position of either the blade or the clamp arm about the longitudinal axis at any of a number of predetermined angular positions.

Abstract: Techniques for media processing and item recognition are provided. A digital media is received from a user. Objects depicted within the digital media are identified. Items currently available at a physical location are determined by analyzing information collected by a set of cameras at the physical location. A set of target items, from the items currently available at the physical location, that are similar to at least one of the objects are identified based on the digital media and the collected information. A guidance that navigates the user to at least one of the set of target items within the physical location is generated.

Abstract: A hedge trimmer and a tool assembly for assembling a blade assembly are provided. The hedge trimmer includes a housing at which a motor is disposed. The blade assembly extends from the housing and includes a blade component forming a blade opening through which a fastener is extendable. A retainer forms a retainer opening through which the fastener is extendable. A second spine opening at a spine extends from a first spine opening at the spine. The second spine opening forms a narrower cross section relative to the first spine opening. The fastener is extendable into the second spine opening from the first spine opening. The retainer is positioned between the spine and the blade component.

Abstract: A system for detecting strokes includes a sensor device configured to obtain physiological data from a patient, for example brain activity data. The sensor device can include electrodes configured to be disposed at the back of the patient's neck or base of the skull. The electrodes can detect electrical signals corresponding to brain activity in the P3, Pz, and/or P4 brain regions or other brain regions. A computing device communicatively coupled to the sensor device is configured to receive the physiological data and analyze it to indicate whether the patient has suffered a stroke.