Patents by Inventor Brian D. Yard

Brian D. Yard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for affecting homology-directed DNA double stranded break repair
    Patent number: 8563243
    Abstract: Disclosed herein are methods and composition for alteration of the presence, activity, or concentration of RNF138. Disclosed methods can be utilized to affect DNA double strand break repair. Methods and compositions can be utilized to alter RNF138 so as to prevent interaction between RNF138 and RAD51D. Specifically, methods can prevent RNF138-directed ubiquitylation of RAD51D, which is necessary for DNA double strand break repair.
    Type: Grant
    Filed: May 11, 2011
    Date of Patent: October 22, 2013
    Assignee: University of South Carolina
    Inventors: Douglas L. Pittman, Brian D. Yard
  • Methods for Affecting Homology-Directed DNA Double Stranded Break Repair
    Publication number: 20120077757
    Abstract: Disclosed herein are methods and composition for alteration of the presence, activity, or concentration of RNF138. Disclosed methods can be utilized to affect DNA double strand break repair. Methods and compositions can be utilized to alter RNF138 so as to prevent interaction between RNF138 and RAD51D. Specifically, methods can prevent RNF138-directed ubiquitylation of RAD51D, which is necessary for DNA double strand break repair.
    Type: Application
    Filed: May 11, 2011
    Publication date: March 29, 2012
    Applicant: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Douglas L. Pittman, Brian D. Yard