Patents by Inventor Brian E. Collins

Brian E. Collins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-acetylhexosamine-containing N-glycans in glycoprotein products
    Patent number: 9170249
    Abstract: The present invention provides methods of evaluating a glycoprotein preparation for the absence, presence or amount of an N-acetylhexosamine glycan, e.g., an N-acetylglucosamine glycan.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: October 27, 2015
    Assignee: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Nathaniel J. Washburn, Enrique Arevalo, Kevin Millea, Carlos J. Bosques, Jay Duffner, Brian E. Collins
  • N-ACETYLHEXOSAMINE-CONTAINING N-GLYCANS IN GLYCOPROTEIN PRODUCTS
    Publication number: 20120295273
    Abstract: The present invention provides methods of evaluating a glycoprotein preparation for the absence, presence or amount of an N-acetylhexosamine glycan, e.g., an N-acetylglucosamine glycan.
    Type: Application
    Filed: March 12, 2012
    Publication date: November 22, 2012
    Inventors: Nathaniel J. Washburn, Enrique Arevalo, Kevin Millea, Carlos J. Bosques, Jay Duffner, Brian E. Collins
  • METHODS OF MODULATING FUCOSYLATION OF GLYCOPROTEINS
    Publication number: 20120277165
    Abstract: The present invention provides methods and materials useful for monitoring and regulating the glycosylation of glycoproteins that are recombinantly produced from cells. In particular, methods are provided for monitoring and regulating levels of cellular indicators which affect the level of fucosylation produced by cells.
    Type: Application
    Filed: June 4, 2010
    Publication date: November 1, 2012
    Inventors: Brian E. Collins, Lakshmanan Thiruneelakantapillai, Dorota A. Bulik, Kevin Millea
  • Compounds for altering cell surface sialic acids and methods of use therefor
    Patent number: 6274568
    Abstract: The present invention is based on the identification of compounds in the form of biosynthetic precursors which can be used to modulate neuronal growth, inhibit cellular entry by pathogens and modulate immune responses. The invention further describes acylated mannosamines, and derivatives thereof, which can be used to alter the sialic acid substituents of sialoglycoconjugates.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: August 14, 2001
    Inventors: Ronald L. Schnaar, Yoshitak Ichikawa, Brian E. Collins, Thomas J. Fralich