Patents by Inventor BRIAN E. SOUZA

BRIAN E. SOUZA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12005099
    Abstract: Targeted antimicrobials are described and related, compositions, methods and systems.
    Type: Grant
    Filed: May 21, 2020
    Date of Patent: June 11, 2024
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Paul J. Jackson, Brian E. Souza, Feliza A. Bourguet, Matthew A. Coleman
  • Publication number: 20210403421
    Abstract: Biodegradable surfactants are described, in which an amphiphilic heteroatom containing hydrocarbon optionally comprising at least one counterion (Z), and related compositions, methods and systems. Biodegradable surfactant described herein has an aHLB value in accordance with equation (1): aHLB=20*Gh/(Gh?Gt) (1) wherein Gh is the Group Number of a hydrophilic head portion of the biodegradable surfactant optionally comprising the at least one counterion (Z), and Gt is the Group Number of a hydrophobic tail portion of the biodegradable surfactant. A biodegradable surfactant in the sense of the disclosure can be tuned to a set hydrophilic-lipophilic balance (aHLB) by selectively modifying at least one tuning moiety of the biodegradable surfactants to provide tuned biodegradable surfactants having an increase or decrease in their adjusted hydrophilic-lipophilic balance (aHLB).
    Type: Application
    Filed: June 17, 2021
    Publication date: December 30, 2021
    Inventors: Mathew Gerald LYMAN, Lawrence DUGAN, Roald N. LEIF, Bonnee RUBINFELD, Brian E. SOUZA, Carlos A. VALDEZ
  • Patent number: 11066359
    Abstract: Biodegradable surfactants are described, in which an amphiphilic heteroatom containing hydrocarbon optionally comprising at least one counterion (Z), and related compositions, methods and systems. Biodegradable surfactant described herein has an aHLB value in accordance with equation (1): aHLB=20*Gh/(Gh?Gt) (1) wherein Gh is the Group Number of a hydrophilic head portion of the biodegradable surfactant optionally comprising the at least one counterion (Z), and Gt is the Group Number of a hydrophobic tail portion of the biodegradable surfactant. A biodegradable surfactant in the sense of the disclosure can be tuned to a set hydrophilic-lipophilic balance (aHLB) by selectively modifying at least one tuning moiety of the biodegradable surfactants to provide tuned biodegradable surfactants having an increase or decrease in their adjusted hydrophilic-lipophilic balance (aHLB).
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: July 20, 2021
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Mathew Gerald Lyman, Lawrence Dugan, Roald N. Leif, Bonnee Rubinfeld, Brian E. Souza, Carlos A. Valdez
  • Publication number: 20200400521
    Abstract: Targeted antimicrobials are described and related, compositions, methods and systems.
    Type: Application
    Filed: May 21, 2020
    Publication date: December 24, 2020
    Inventors: Paul J. JACKSON, Brian E. SOUZA, Feliza A. BOURGUET, Matthew A. COLEMAN
  • Patent number: 10688163
    Abstract: Targeted antimicrobials are described and related, compositions, methods and systems.
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: June 23, 2020
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Paul J. Jackson, Brian E. Souza, Feliza A. Bourguet, Matthew A. Coleman
  • Publication number: 20190359562
    Abstract: Biodegradable surfactants are described, in which an amphiphilic heteroatom containing hydrocarbon optionally comprising at least one counterion (Z), and related compositions, methods and systems. Biodegradable surfactant described herein has an aHLB value in accordance with equation (1): aHLB=20*Gh/(Gh?Gt) (1) wherein Gh is the Group Number of a hydrophilic head portion of the biodegradable surfactant optionally comprising the at least one counterion (Z), and Gt is the Group Number of a hydrophobic tail portion of the biodegradable surfactant. A biodegradable surfactant in the sense of the disclosure can be tuned to a set hydrophilic-lipophilic balance (aHLB) by selectively modifying at least one tuning moiety of the biodegradable surfactants to provide tuned biodegradable surfactants having an increase or decrease in their adjusted hydrophilic-lipophilic balance (aHLB).
    Type: Application
    Filed: February 8, 2018
    Publication date: November 28, 2019
    Inventors: Mathew Gerald LYMAN, Lawrence DUGAN, Roald N. LEIF, Bonnee RUBINFELD, Brian E. SOUZA, Carlos A. VALDEZ
  • Publication number: 20140369990
    Abstract: Targeted antimicrobials are described and related, compositions, methods and systems.
    Type: Application
    Filed: August 11, 2014
    Publication date: December 18, 2014
    Inventors: Paul J. JACKSON, Brian E. SOUZA, Feliza A. BOURGUET, Matthew A. COLEMAN
  • Patent number: 8821860
    Abstract: Targeted antimicrobials are described and related, compositions, methods and systems.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: September 2, 2014
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Paul J. Jackson, Brian E. Souza, Feliza A. Bourguet, Matthew A. Coleman
  • Publication number: 20110033439
    Abstract: Targeted antimicrobials are described and related, compositions, methods and systems.
    Type: Application
    Filed: August 6, 2010
    Publication date: February 10, 2011
    Inventors: PAUL L. JACKSON, BRIAN E. SOUZA, FELIZA A. BOURGUET, MATTHEW A. COLEMAN