Abstract: Disclosed is a system (100) and method for tracking an inventory item (102, 202, 304) within a facility. The system comprises a unique identification tag (208, 306) for the inventory item and a plurality of cameras (104, 106, 204, 206) positioned within the facility. The unique identification tag is visible in images (302, 308, 312) captured by at least one of the plurality of cameras. An image processor (108) configured to receive at least one image of the inventory item from at least one of the plurality of cameras. The image processor identifies one or more parameters such as a type, a class, a state associated with the inventory item from the at least one image. The image processor further identifies the unique identification tag from the at least one image and identify the inventory item associated with it. The image processor employs at least one of: computer vision, neural networks, image processing algorithms for processing of the image.

Abstract: Disclosed is a system and a method for managing traffic in an environment comprising at least one operational vehicle and at least one autonomous vehicle therein.

Abstract: Disclosed is a system arranged to track a surgical kit comprising a container and one or more surgical tools. The system comprises a unique identification tag for container and a unique identification tag for one or more surgical tools; and an image processor configured to receive at least one image of unique identification tag for container and/or unique identification tag for one or more surgical tools captured by at least one imaging arrangement and process at least one image to: identify unique identification tag for container and/or one or more surgical tools, determine identity of container and/or one or more surgical tools based on one or more parameters identified from unique identification tag, and track a location of container and/or one or more surgical tools, based on a location of at least one imaging arrangement that captured the image of container and/or one or more surgical tools.

Abstract: Disclosed is a system and a method for geo-referencing an object on a floor. The method comprises receiving a camera frame providing view of a section of the floor, receiving a detailed floor plan of the floor, selecting a first area from the section of the floor in which the object needs to be tracked and defining a plurality of reference points. Herein, at least one of the pluralities of reference points is close to a mid-point along one of corresponding axes of the first area. The method further comprises mapping the plurality of reference points to the floor plan, processing the camera frame to determine if the object has been placed in the first area and geo-referencing the one or more object in the floor plan if the object is determined to be placed in the first area.

Abstract: Methods and apparatus are described for sensing misplacement of an optical sensor on a patient. A wavelength of light which is particularly subject to absorption by a physiological characteristic of interest is used to compare to a reference to determine if the sensor placement is appropriate, such as to generate accurate readings. In one example, the intensity of a wavelength of light which is subject to absorption by bulk tissue, but less subject to absorption by oxygen in the blood will be detected to evaluate the placement of the sensor.

Abstract: A method for manufacturing a tissue factor-based prothrombin-time reagent includes combining predetermined quantities of tissue factor (TF), phospholipid and detergent-containing buffer to create a TF/phospholipid mixture. In this combining step, the quantity of TF is predetermined based upon its measured TF activity. Next, the detergent is removed from the TF/phospholipid mixture to produce an essentially detergent-free TF/phospholipid mixture that is useful as a tissue factor-based PT reagent. The method can include the use of hydrophobic resin that has been prescreened based on phospholipid recovery to accomplish the removal of the detergent.

Abstract: Compositions, methods, devices and kits for use in the calibration of coagulation tests. The control compositions comprise particles capable of aggregating in plasma and calcium ions which, when mixed with plasma, simulate the behavior of whole blood in a coagulation test. The methods comprise providing calcium ions and particles capable of aggregating in plasma, combining the particles and calcium ions with plasma to form a control composition, and applying the control composition to a coagulation test. The devices comprise a container having at least two compartments, with one compartment including particles that promote or induce aggregation of a protein or proteins in plasma, and the other compartment includes a solution of calcium ions. The kits comprise a control composition comprising a container of calcium ions, a container of particles capable of inducing aggregation of proteins in plasma, and one or more coagulation test devices.

Abstract: Compositions, methods, devices and kits for use in the calibration of coagulation tests. The control compositions include particles capable of aggregating in plasma and calcium ions which, when mixed with plasma, simulate the behavior of whole blood in a coagulation test. The methods include providing calcium ions and particles capable of aggregating in plasma, combining the particles and calcium ions with plasma to form a control composition, and applying the control composition to a coagulation test. The devices include a container having at least two compartments, with one compartment including particles that promote or induce aggregation of a protein or proteins in plasma, and the other compartment includes a solution of calcium ions. The kits include a control composition including a container of calcium ions, a container of particles capable of inducing aggregation of proteins in plasma, and one or more coagulation test devices.

Abstract: A computer system for the closed-loop support of patient self-testing includes data repository, healthcare provider interface, training interface, supplier, patient interface and analysis modules. The data repository module is configured to store patient enrollment and patient self-test information. The healthcare provider interface module is configured to receive patient enrollment and modified patient prescription information furnished by a healthcare provider and to transfer these to the data repository module. The healthcare provider interface module is also configured to communicate patient self-test result information to a healthcare provider. The training module is configured to receive patient diagnostic monitoring device training information and to transfer that information to the data repository module.

Abstract: A method for manufacturing a tissue factor-based prothrombin-time reagent includes combining predetermined quantities of tissue factor (TF), phospholipid and detergent-containing buffer to create a TF/phospholipid mixture. In this combining step, the quantity of TF is predetermined based upon its measured TF activity. Next, the detergent is removed from the TF/phospholipid mixture to produce an essentially detergent-free TF/phospholipid mixture that is useful as a tissue factor-based PT reagent. The method can include the use of hydrophobic resin that has been prescreened based on phospholipid recovery to accomplish the removal of the detergent.

Abstract: Compositions, methods, devices and kits for use in the calibration of coagulation tests. The control compositions comprise particles capable of aggregating in plasma and calcium ions which, when mixed with plasma, simulate the behavior of whole blood in a coagulation test. The methods comprise providing calcium ions and particles capable of aggregating in plasma, combining the particles and calcium ions with plasma to form a control composition, and applying the control composition to a coagulation test. The devices comprise a container having at least two compartments, with one compartment including particles that promote or induce aggregation of a protein or proteins in plasma, and the other compartment includes a solution of calcium ions. The kits comprise a control composition comprising a container of calcium ions, a container of particles capable of inducing aggregation of proteins in plasma, and one or more coagulation test devices.