Patents by Inventor Brian F. Volkman

Brian F. Volkman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered CCL20 locked dimer polypeptide
    Patent number: 11571462
    Abstract: The present invention provides a CCL20 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of psoriasis and psoriatic arthritis.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: February 7, 2023
    Assignee: The Medical College of Wisconsin, Inc.
    Inventors: Brian F. Volkman, Anthony E. Getschman, Sam T. Hwang, Yasutomo Imai, Francis C. Peterson
  • Methods of Treating Vascular Leakage Using CXCL12 Peptides
    Publication number: 20210052701
    Abstract: The present invention relates to methods for treatment of capillary leak syndrome and acute respiratory distress syndrome using CXCL12 peptides, specifically a constitutively monomeric CXCL12 peptide or a CXCL12 locked dimer polypeptide.
    Type: Application
    Filed: October 27, 2020
    Publication date: February 25, 2021
    Inventors: Brian F. Volkman, Matthias Majetschak, You-Hong Cheng
  • ENGINEERED CCL20 LOCKED DIMER POLYPEPTIDE
    Publication number: 20200360479
    Abstract: The present invention provides a CCL20 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of psoriasis and psoriatic arthritis.
    Type: Application
    Filed: July 30, 2020
    Publication date: November 19, 2020
    Inventors: Brian F. Volkman, Anthony E. Getschman, Sam T. Hwang, Yasutomo Imai, Francis C. Peterson
  • Engineered CCL20 locked dimer polypeptide
    Patent number: 10738095
    Abstract: The present invention provides a CCL20 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of psoriasis, inflammatory disorders and autoimmune disease.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: August 11, 2020
    Assignee: The Medical College of Wisconsin, Inc.
    Inventors: Brian F. Volkman, Anthony E. Getschman, Sam T. Hwang, Yasutomo Imai, Francis C. Peterson
  • METHODS OF TREATING VASCULAR LEAKAGE USING CXCL12 PEPTIDES
    Publication number: 20190374607
    Abstract: The present invention relates to methods for treatment of capillary leak syndrome and acute respiratory distress syndrome using CXCL12 peptides, specifically a constitutively monomeric CXCL12 peptide or a CXCL12 locked dimer polypeptide.
    Type: Application
    Filed: June 7, 2019
    Publication date: December 12, 2019
    Inventors: Brian F. Volkman, Matthis Majetschak, You-Hong Cheng
  • AN ENGINEERED CCL20 LOCKED DIMER POLYPEPTIDE
    Publication number: 20180237486
    Abstract: The present invention provides a CCL20 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of psoriasis, inflammatory disorders and autoimmune disease.
    Type: Application
    Filed: May 31, 2016
    Publication date: August 23, 2018
    Inventors: Brian F. Volkman, Anthony E. Getschman, Sam T. Hwang, Yasutomo Imai, Francis C. Peterson
  • ENGINEERED CXCL12 ALPHA LOCKED DIMER POLYPEPTIDE
    Publication number: 20160229900
    Abstract: The present invention provides a novel CXCL12-?2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
    Type: Application
    Filed: April 15, 2016
    Publication date: August 11, 2016
    Inventors: Brian F. Volkman, Christopher T. Veldkamp, Francis C. Peterson, Thomas Sakmar, Christoph H. Seibert
  • Engineered CXCL12 alpha locked dimer polypeptide
    Patent number: 9346871
    Abstract: The present invention provides a novel CXCL12-?2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: May 24, 2016
    Assignees: The Medical College of Wisconsin, The Rockefeller University
    Inventors: Brian F. Volkman, Christopher T. Veldkamp, Francis C. Peterson, Thomas Sakmar, Christoph H. Seibert
  • ENGINEERED CXCL12 ALPHA LOCKED DIMER POLYPEPTIDE
    Publication number: 20130316944
    Abstract: The present invention provides a novel CXCL12-?2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
    Type: Application
    Filed: July 8, 2013
    Publication date: November 28, 2013
    Applicants: The Rockefeller University, Medical College of Wisconsin Research Foundation
    Inventors: Brian F. Volkman, Christopher T. Veldkamp, Francis C. Peterson, Thomas Sakmar, Christoph H. Seibert
  • Engineered CXCL12 alpha locked dimer polypeptide
    Patent number: 8524670
    Abstract: The present invention provides a novel CXCL12-?2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: September 3, 2013
    Assignees: Medical College of Wisconsin Research Foundation, The Rockefeller University
    Inventors: Brian F. Volkman, Christopher T. Veldkamp, Francis C. Peterson, Thomas Sakmar, Christoph H. Seibert
  • Engineered CXCL12 Alpha Locked Dimer Polypeptide
    Publication number: 20110091410
    Abstract: The present invention provides a novel CXCL12-?2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
    Type: Application
    Filed: November 30, 2010
    Publication date: April 21, 2011
    Applicant: Medical College of Wisconsin Research Foundation
    Inventors: Brian F. Volkman, Christopher T. Veldkamp, Francis C. Peterson, Thomas Sakmar, Christoph H. Seibert
  • Engineered CXCL12 ? locked dimer polypeptide
    Patent number: 7923016
    Abstract: The present invention provides a novel CXCL12-?2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: April 12, 2011
    Assignees: Medical College of Wisconsin, Rockefeller University
    Inventors: Brian F. Volkman, Christopher T. Veldkamp, Francis C. Peterson, Thomas Sakmar, Christoph H. Seibert
  • Engineered CXCL 12 alpha locked dimer polypeptide
    Publication number: 20090305984
    Abstract: The present invention provides a novel CXCL12-?2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
    Type: Application
    Filed: February 26, 2009
    Publication date: December 10, 2009
    Applicant: Medical College of Wisconsin Research Foundation
    Inventors: Brian F. Volkman, Christopher T. Veldkamp, Francis C. Peterson, Thomas Sakmar, Christoph H. Seibert