Abstract: A urine collection assembly includes a urine collection device and a urine collection chamber in communication with the urine collection device. The urine collection chamber includes a collection reservoir, an entrance conduit having an inlet to receive urine from the urine collection device and an outlet terminating in the reservoir, an anti-reflux valve, and an exit conduit. The collection reservoir is configured to be wearable in close proximity to a user's body below the waist and above the knees of the user. The collection reservoir holds urine excreted from a user. The exit conduit enables drainage of the collection reservoir. The exit conduit also enables attachment of the collection reservoir to an additional conventional urine collection chamber. The anti-reflex valve is configured to prevent urine from backing up out of the urine collection chamber and into the urine collection device.