Abstract: A paracorporeal respiratory assist lung is configured with an annular cylindrical hollow fiber membrane (fiber bundle) that is rotated at rapidly varying speeds. Fluid (for example, blood) is introduced to the center of the device and is passed radially through the fiber bundle. The bundle is rotated at rapidly changing velocities with a rotational actuator (for example, a motor or magnetic coupling). The rotation of the fiber bundle provides centrifugal kinetic energy to the fluid giving the device pumping capabilities and may create Taylor vortexes to increase mass transfer. Rotation of the fiber bundle increases the relative velocity between the fluid and the hollow fibers and increases the mass transfer. The porosity of the fiber bundle may be varied to enhance gas exchange with the blood. Alternatively, a rotating core may be used with a stationary fiber bundle.

Abstract: A compact,intravenous, percutaneous respiratory assist catheter having a rotating fiber bundle functions as an intravenous oxygenerator configured to be implanted within the patient's vasculature. The respiratory assist catheter provides oxygen introduction and carbon dioxide removal from the blood of the patient. the catheter includes hollow, gas-permeable fibers extending between a distal manifoldand a proximal manifold that permit diffusion of gases between the blood vessel and the interior of the fibers. An implantable version of the catheter is configured with a fiber bundle having increased porosity and with a mechanism to prevent the fiber bundle from damaging the vena cava. The fiber bundle may be protected by a wire loom or coil cage made from materials such as nitinol and stainless steel. The rotation of the fiber bundle may be varied in speed and in direction.