Patents by Inventor Brian Frostrup

Brian Frostrup has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions of 5-hydroxytryptophan and serotonin-enhancing compound
    Patent number: 9901568
    Abstract: This invention relates to novel pharmaceutical compositions comprising a therapeutically effective amount of a slow-release formulation of 5-hydroxytryptophan (5-HTP) and a serotonin-enhancing compound. The pharmaceutical compositions for use according to the invention are contemplated particularly useful for combating CNS disorders, including depressive disorders, bipolar disorders, anxiety disorders, obesity and pain.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: February 27, 2018
    Assignee: Duke University
    Inventors: Jacob Pade Ramsoe Jacobsen, Brian Frostrup
  • Hydrobromide salt of pridopidine
    Patent number: 9814706
    Abstract: This invention relates to a new salt of Pridopidine, a drug substance currently in development for the treatment of Huntington's disease. More specifically the invention provides the pharmaceutically acceptable hydrobromide salt, pharmaceutical compositions comprising this salt, and uses of this salt as a drug substance.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: November 14, 2017
    Assignee: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Anne Zimmermann, Brian Frøstrup
  • HYDROBROMIDE SALT OF PRIDOPIDINE
    Publication number: 20150209344
    Abstract: This invention relates to a new salt of Pridopidine, a drug substance currently in development for the treatment of Huntington's disease. More specifically the invention provides the pharmaceutically acceptable hydrobromide salt, pharmaceutical compositions comprising this salt, and uses of this salt as a drug substance.
    Type: Application
    Filed: February 4, 2015
    Publication date: July 30, 2015
    Applicant: IVAX INTERNATIONAL GMBH
    Inventors: Anne ZIMMERMANN, Brian FRØSTRUP
  • PHARMACEUTICAL COMPOSITIONS OF 5-HYDROXYTRYPTOPHAN AND SEROTONIN-ENHANCING COMPOUND
    Publication number: 20150133499
    Abstract: This invention relates to novel pharmaceutical compositions comprising a therapeutically effective amount of a slow-release formulation of 5-hydroxytryptophan (5-HTP) and a serotonin-enhancing compound. The pharmaceutical compositions for use according to the invention are contemplated particularly useful for combating CNS disorders, including depressive disorders, bipolar disorders, anxiety disorders, obesity and pain.
    Type: Application
    Filed: January 26, 2015
    Publication date: May 14, 2015
    Inventors: Jacob Pade Ramsoe Jacobsen, Brian Frostrup
  • Hydrobromide salt of pridopidine
    Patent number: 9012476
    Abstract: This invention relates to a new salt of Pridopidine, a drug substance currently in development for the treatment of Huntington's disease. More specifically the invention provides the pharmaceutically acceptable hydrobromide salt, pharmaceutical compositions comprising this salt, and uses of this salt as a drug substance.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: April 21, 2015
    Assignee: Ivax International GmbH
    Inventors: Anne Zimmermann, Brian Frøstrup
  • Polymorphic form of pridopidine hydrochloride
    Patent number: 9006445
    Abstract: This invention relates to a new crystalline form of Pridopidine, a drug substance currently in development for the treatment of Huntington's disease. More specifically the invention provides polymorphic Form II of the Pridopidine hydrochloride salt, a process for the preparation of this polymorphic form, pharmaceutical compositions comprising polymorphic Form II, and methods of uses of this polymorphic form.
    Type: Grant
    Filed: September 6, 2012
    Date of Patent: April 14, 2015
    Assignee: Ivax International GmbH
    Inventors: Clas Sonesson, Thomas Pittelkow, Brian Frøstrup, Anne Zimmermann
  • Pharmaceutical compositions of 5-hydroxytryptophan and serotonin-enhancing compound
    Patent number: 8969400
    Abstract: This invention relates to novel pharmaceutical compositions comprising a therapeutically effective amount of a slow-release formulation of 5-hydroxytryptophan (5-HTP) and a serotonin-enhancing compound. The pharmaceutical compositions for use according to the invention are contemplated particularly useful for combating CNS disorders, including depressive disorders, bipolar disorders, anxiety disorders, obesity and pain.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: March 3, 2015
    Assignee: Duke University
    Inventors: Jacob Pade Ramsoe Jacobsen, Brian Frøstrup
  • POLYMORPHIC FORM OF PRIDOPIDINE HYDROCHLORIDE
    Publication number: 20140315951
    Abstract: This invention relates to a new crystalline form of Pridopidine, a drug substance currently in development for the treatment of Huntington's disease. More specifically the invention provides polymorphic Form II of the Pridopidine hydrochloride salt, a process for the preparation of this polymorphic form, pharmaceutical compositions comprising polymorphic Form II, and methods of uses of this polymorphic form.
    Type: Application
    Filed: September 6, 2012
    Publication date: October 23, 2014
    Applicant: IVAX INTERNATIONAL GMBH
    Inventors: Clas Sonesson, Thomas Pittelkow, Brian Frøstrup, Anne Zimmermann
  • Enantiomers of 3-heteroaryl-8H-8-azabicyclo(3.2.1)oct-2-ene and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7781456
    Abstract: This invention relates to novel enantiomers useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: August 24, 2010
    Assignee: Neurosearch A/S
    Inventors: Dan Peters, David Tristram Brown, Börje Egestad, Sinikka Marjatta Taurio, legal representative, Eva Dam, David Spencer Jones, Brian Frøstrup, Elsebet Østergaard Nielsen, Gunnar M. Olsen, John Paul Redrobe
  • 2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts
    Patent number: 7700619
    Abstract: This invention relates to novel (1R,2R,3S,5S)-2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts, such as L-tartrate monohydrates and anhydrates, wherein the salts are useful as monoamine neurotransmitter re-uptake inhibitors. Additionally, the invention also relates to the use of these salts in a method for therapy and to pharmaceutical compositions comprising the salts of the invention.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: April 20, 2010
    Assignee: Neurosearch A/S
    Inventors: Brian Frøstrup, Frank Wätjen, Klaus Snej Jensen
  • Enantiomers of 3-Heteroaryl-8H-8-Azabicyclo (3.2.1) Oct-2-Ene and their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20080214820
    Abstract: This invention relates to novel enantiomers useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: December 15, 2005
    Publication date: September 4, 2008
    Applicant: NeuroSearch A/S
    Inventors: Dan Peters, David Tristram Brown, Borje Egestad, Eva Dam, David Spencer Jones, Brian Frostrup, Elsebet Ostergaard Nielsen, Gunnar M. Olsen, John Paul Redrobe
  • 2-Methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts
    Publication number: 20070043075
    Abstract: This invention relates to novel (1R,2R,3S,5S)-2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts, such as L-tartrate monohydrates and anhydrates. The salts are useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these salts in a method for therapy and to pharmaceutical compositions comprising the salts of the invention.
    Type: Application
    Filed: July 29, 2004
    Publication date: February 22, 2007
    Inventors: Brian Frostrup, Frank Watjen, Klaus Jensen