Patents by Inventor Brian FURY

Brian FURY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRISPR/CAS SCREENING PLATFORM TO IDENTIFY GENETIC MODIFIERS OF TAU SEEDING OR AGGREGATION
    Publication number: 20240084293
    Abstract: Cas-protein-ready tau biosensor cells, CRISPR/Cas synergistic activation mediator (SAM)-ready tau biosensor cells, and methods of making and using such cells to screen for genetic modifiers of tau seeding or aggregation are provided. Reagents and methods for sensitizing such cells to tau seeding activity or tau aggregation or for causing tau aggregation are also provided.
    Type: Application
    Filed: November 6, 2023
    Publication date: March 14, 2024
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Marine Prissette, Matthew Koss, Wen Fury, Brian Zambrowicz
  • NEURAL STEM CELL COMPOSITIONS AND METHODS TO TREAT NEURODEGENERATIVE DISORDERS
    Publication number: 20210228644
    Abstract: Provided herein are stem-cell based therapies for the treatment of neurodegenerative diseases and CNS disorder such as Huntington's disease. The therapy improved motor deficits and rescued synaptic alterations. The cells were shown to be electrophysiologically active and that they improved motor and late-stage cognitive impairment.
    Type: Application
    Filed: June 6, 2018
    Publication date: July 29, 2021
    Applicant: The Regents of the University of California
    Inventors: John REIDLING, Brian FURY, Leslie Michels THOMPSON, Gerhard Bauer, Dane COLEAL-BERGUM
  • METHODS FOR ENHANCED PRODUCTION AND ISOLATION OF CELL-DERIVED VESICLES AND TREATMENT OF INFLAMMATION AND NEUROLOGICAL DAMAGE
    Publication number: 20200113943
    Abstract: This disclosure relates to populations and compositions of purified cell-derived vesicles and uses thereof. One aspect of the disclosure relates to methods for purifying the cell-derived vesicles.
    Type: Application
    Filed: June 5, 2018
    Publication date: April 16, 2020
    Inventors: Johnathon D. ANDERSON, Jan A. NOLTA, Gerhard BAUER, Brian FURY
  • METHODS FOR ENHANCED PRODUCTION AND ISOLATION OF CELL-DERIVED VESICLES
    Publication number: 20190008902
    Abstract: This disclosure relates to populations and compositions of purified cell-derived vesicles and uses thereof. One aspect of the disclosure relates to methods for purifying the cell-derived vesicles.
    Type: Application
    Filed: December 30, 2016
    Publication date: January 10, 2019
    Inventors: Johnathon D. ANDERSON, Jan A. NOLTA, Gerhard BAUER, Brian FURY