Patents by Inventor Brian G. Cox

Brian G. Cox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical process for the preparation of a 2-hydroxyarylaldehyde
    Patent number: 5354920
    Abstract: A method for the preparation of a 2-hydroxyarylaldehyde which comprises reacting an aryloxymagnesium halide derived from a phenol having at least one free ortho position relative to the phenolic hydroxy group with formaldehyde or a formaldehyde-liberating compound under substantially anhydrous conditions in the presence of a polar organic solvent other than hexamethylphosphoramide or 1,3-dimethyl-3,4,5,6-2(1H)-pyrimidone.
    Type: Grant
    Filed: August 10, 1993
    Date of Patent: October 11, 1994
    Assignee: Zeneca Limited
    Inventors: Brian G. Cox, Daniel Levin
  • Method of preparing pyridazinone derivatives
    Patent number: 5189163
    Abstract: A method for the preparation of a pyridazinone derivative having the general formula I: ##STR1## where: R.sup.1 is a phenyl group, optionally substituted, R.sup.2 is H, alkyl or carboxy, R.sup.3 is H, alkyl or alkoxy and R.sup.4 is alkyl; said method comprising reacting a hydrazone of glyoxylic acid halide having the formula VII: ##STR2## in which X is halogen, with an ester of formula VIII; ##STR3## in the presence of an alkaline earth base.
    Type: Grant
    Filed: March 13, 1992
    Date of Patent: February 23, 1993
    Assignee: Imperial Chemical Industries PLC
    Inventors: Brian G. Cox, Michael S. Howarth