Patents by Inventor Brian G. Wowk

Brian G. Wowk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for rapid cooling and warming of biological materials
    Patent number: 6274303
    Abstract: A method of cooling and rewarming large organs and tissues at sub-zero temperatures is provided. The method includes perfusion of tissue with inert fluids that remain liquid at very low temperatures. The inert fluids can include fluorocarbons, silicones, or fluorosilicones. Glycol ethers are used as a novel class of cryoprotective agents for organ and tissue preservation. The glycol ethers have improved viscosity, penetration, and glass forming properties.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: August 14, 2001
    Inventors: Brian G. Wowk, Michael G. Federowicz, Sandra R. Russell, Steven B. Harris
  • Method for vitrification of biological materials using alkoxylated compounds
    Patent number: 5952168
    Abstract: A method of cryopreserving biological material by administering a cryoprotective agent mixture is provided. The mixture must be produced in a concentration sufficient to permit vitrification. The cryoprotective agent is an alkoxylated organic compound. The method includes administering the cryoprotective agent mixture and cooling the biological material until it is vitrified. Preferred cryoprotective mixtures contain 3 methoxy-1,2 propanediol and 2-methoxy ethanol.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: September 14, 1999
    Assignee: 21st Century Medicine, Inc.
    Inventors: Brian G. Wowk, Michael G. Federowicz, Sandra R. Russell, Steven B. Harris