Abstract: A reference electrode assembly for an electrochemical cell of a secondary lithium ion battery and methods of manufacturing the same. The reference electrode assembly includes a porous membrane having a major surface and a porous reference structure deposited on the major surface of the porous membrane. The porous reference structure includes a porous carbon layer and a porous reference electrode layer that at least partially overlaps the porous carbon layer on the major surface of the porous membrane.

Abstract: An optical assembly a substrate having a first surface and a second surface that is opposite to and substantially parallel with the first surface. The first surface has a first curved profile and the second surface has a second curved profile. The optical assembly also includes a beam splitter on the first surface and a reflector on the second surface. The optical assembly is configured to transmit image light received at the first surface in an optical path that includes reflection at each of the reflector and the beam splitter before the image light is output from the second surface. The optical assembly is also configured to transmit ambient light received at the first surface such that the second light is output from the second surface without undergoing reflection at either the reflector or the beam splitter. A method of transmitting light through the optical assembly is also disclosed.

Abstract: Machine learning systems and methods are disclosed for prediction of wound healing, such as for diabetic foot ulcers or other wounds, and for assessment implementations such as segmentation of images into wound regions and non-wound regions. Systems for assessing or predicting wound healing can include a light detection element configured to collect light of at least a first wavelength reflected from a tissue region including a wound, and one or more processors configured to generate an image based on a signal from the light detection element having pixels depicting the tissue region, determine reflectance intensity values for at least a subset of the pixels, determine one or more quantitative features of the subset of the plurality of pixels based on the reflectance intensity values, and generate a predicted or assessed healing parameter associated with the wound over a predetermined time interval.

Abstract: Embodiments of the present disclosure provide methods, systems, apparatuses, and computer program products for proactive network diagnosis. An example method may include determining, by one or more processors, telemetry data and streaming trap data indicative of a group of cable modem devices being disconnected from a cable network. The example method may include determining, based on the telemetry data and streaming trap data, a first network node device of the group of network node devices. The example method may include generating first performance data associated with the first network node device. The example method may include determining, based on a comparison between the first performance data and an event criterion, an occurrence of an event associated with the first network node device.

Abstract: The application provides anti-4-1BB monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.

Abstract: A computer system accesses a storage device. Contents of an object of a request are sorted. The contents of an object of a request are sorted. A hash key is generated to access information in the storage device based on the sorted contents of the object, wherein objects with non-critical differences are mapped to the same hash key. The information in the storage device is accessed based on the generated hash key to produce a response to the request. Embodiments of the present invention further include a method and program product for accessing a storage device in substantially the same manner described above.

Abstract: The application provides anti-4-1BB monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.

Abstract: Preamble puncturing configuration information is encoded in a pad field, and alternatively or additionally, in a Service Field, depending on a transmission bandwidth of a Physical Layer Convergence Protocol (PLCP) Protocol Data Unit (PPDU). Some implementations also encode one or more parity bits in the pad field or Service field. The PPDU including the preamble puncturing configuration information encodes, in various embodiments, a request to send frame, a clear to send frame, a power save poll frame, or a contention free end frame.

Abstract: The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making such proteins. The disclosure provides methods of inducing an immune response in a subject as well as methods for treating or preventing cancer in a subject by administering the proteins, nucleic acid molecules and/or compositions to the subject.