Abstract: The present invention generally relates to oral compositions such as toothpastes, toothpowders, liquid dentrifices, mouthwashes, rinses, dental floss, denture cleansers, chewing gums, lozenges and the like. In particular, it relates to such oral compositions that include cesium and rubidium salts. In one aspect of the present invention, a composition for oral use is provided. The composition includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2. In another aspect of the present invention, a method for improving oral hygiene in a mammal is provided. The method involves taking a volume of a solution into the mammal's mouth, where the solution includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2, swishing the solution around and expelling the solution.

Abstract: This invention encompasses an expeditious method and compositions that have been found to show selective cytotoxicity against several different cancer cell lines. for treating a wide variety cancer neoplasms that have tumor microenvironments by administering a stand-alone anti-tumor chemotherapeutic composition or administered as an adjunct with chemotherapy and/or radiotherapy with enhanced tumor site affinity that preferentially elevates the pH at the tumor site to suppress and eliminates the acidic tumor microenvironment, administered as chemosensitizing and/or radiosensitizers enhancing the tumor, suppression, remission and inhibit tumor metastisis. The invention encompasses controlling mechanisms of intracellular and extracellular ionic physiology through the administration of alkali salts for pH modulating and for restoring and enhancing ionic physiology.

Abstract: This invention encompasses an expeditious method and composition for treating a wide variety of wounds and injuries by promoting the elevation of pH at the site of injury, enhancing the reduction or elimination of pain and scaring from the patho-physiological process of infection proliferation, and promoting enhanced wound care management and wound healing. The invention also provides a method of treating a subject having a condition associated with the presence of free radicals in quantities sufficient to cause undesirable symptoms. The invention encompasses controlling mechanisms of intracellular and extra-cellular ionic physiology through the administration of a composition which includes alkaline salts preferably cesium salts, for pH modulating and for restoring and enhancing the localized cellular ionic physiology. The composition promotes the increase of the electrical current density to certain types of wounds and also functions to treat and/or prevent adhesions resulting from surgeries.

Abstract: The present invention generally relates to methods, compositions and systems for preventing the common cold and flu, for reducing the duration of common colds and flu, for reducing the severity of common cold and flu symptoms and for reducing/eliminating the transmission of the common cold and flu. Specifically, it relates to the treatment a of subject having a cold with a composition comprising cesium and/or rubidium ions. In a composition aspect, the present invention provides a composition for treating a common cold and flu.

Abstract: Methods and systems for selecting oligonucleotide probes for use in microarray applications are provided herein. The described methods use a combination of measured probe performance and predicted probe performance to select probes. Nucleic acid arrays containing probes selected by the described methods are described. Also included are algorithms for performing the subject methods recorded on computer-readable media and computational systems for analysis.

Abstract: The present invention relates to methods and compositions for the prevention, suppression and elimination of oral pain. Specifically, it relates to methods and compositions including cesium and/or rubidium that are used to treat or prevent oral pain. In a method aspect of the present invention, a method of treating oral pain in a mammal is provided. The method involves topically administering or injecting a composition to the oral cavity of the mammal, and wherein the composition comprises from 500 ppm to 100,000 ppm of a cesium ion source, a rubidium ion source, or a mixture of the two.

Abstract: The methods and compositions of the present invention generally relate to ophthalmic solutions. Specifically, the methods and compositions relate to at least the following: ophthalmic solutions that are usable as eye drops for contact lens wearers, eye rinsing solutions, and ophthalmic solutions that are usable as contact lens wetting agents. In a wetting solution aspect, the present invention provides a contact lens wetting solution that includes: a cesium salt, a rubidium salt or a combination thereof; and, water, wherein the wetting solution has a viscosity of 1 to 3 cps.

Abstract: The present invention relates to the fields of pharmacology, regenerative medicine, electro-physiology, and stem cell therapy. In a method aspect, a method of stimulating stem cell release in a mammal is provided. The method includes the step of administering a composition to the mammal, and wherein the composition comprises from 500 ppm to 100,000 ppm of a cesium ion source, a rubidium ion source, or a mixture of the two.

Abstract: Provided is a street sweeper for collecting debris from a street surface. The street sweeper includes a chassis mounted on wheels, a rotating broom for removing debris from a street surface, and a hopper for collecting the removed debris. A passageway extends between the broom and the hopper to transfer the debris removed from the street surface. To remove debris from areas difficult to access with the rotating broom, the street sweeper also includes a litter hose connected to an air flow generating device that communicates with the hopper. The airflow generating device provides a suction force within the litter hose for removing debris and discharges that debris into the hopper. The airflow generating device and suction force work independently of the internal conditions of the hopper. In an embodiment, the airflow discharged into the hopper can exhaust through the passageway extending between the broom and the hopper.

Abstract: This present invention provides compositions and methods for Longevity Assurance and treatment of disorders associated with age-related diseases. The compositions and methods further address age-related or incorrect or abnormal regulation of cellular homeostasis by controlling mechanisms of systemic, intracellular and extracellular ionic physiology through the administration of alkaline salts. The therapy described corrects molecular and ionic pathology, promoting Longevity Assurance with disease resistance.

Abstract: The invention discloses an expeditious method and formula for treating cancer patients that reaulst in tumor suppression and remission, the suppression of mobilization and adhesion of cancer cells, and repression of pathogens, such as infectious bacteria and viruses. Administration is by oral ingestion or direct injection into tumors or intravenous drip etc. The invention employs control of intracellular and extracelular ionic physiology by administering alkaline salts, thereby restoring localized and/or systemic cellular ionic physiology, depriving cancerous cells of their ability to grow rapidly, and simultaneously normalizing their local environment, thereby inhibiting angiogenesis, enabling immune responses, and simultaneously reducing pain. The method further promotes correction of acidotic conditions often associated with cancer and other diseases, thereby potentiating biological functions of immunity and repair.

Abstract: The present invention generally relates to oral compositions such as toothpastes, toothpowders, liquid dentrifices, mouthwashes, rinses, dental floss, denture cleansers, chewing gums, lozenges and the like. In particular, it relates to such oral compositions that include cesium and rubidium salts. In one aspect of the present invention, a composition for oral use is provided. The composition includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2. In another aspect of the present invention, a method for improving oral hygiene in a mammal is provided. The method involves taking a volume of a solution into the mammal's mouth, where the solution includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2, swishing the solution around and expelling the solution.

Abstract: A carrier for transporting bicycles on the front of a motor vehicle allowing unrestricted access to vehicle trunk, rear cargo area, and top luggage rack. Carrier frame has a horizontal crossmember (10) and two vertical uprights (12). Two removable bicycle support arm assemblies (14) with safety tips extend forward from the crossmember (10). A protector sleeve (22) as part of arm assembly (14) protects bicycle finish at point of contact. An adaptable system comprised of elastic cord assemblies (42) and eyebolts (14, 16, & 18) secures bicycles to the carrier. Carrier mounts to vehicle at top surface of grill and front surface of bumper--four points, mirror image. Custom-designed mounting kits accommodate carrier to a multitude of vehicle makes and models while maintaining a low forward profile for Carrier and bicycle. Eyebolts (14, 16, and 18) serve as structural members, a system component for securing bicycles, attaching hardware, and a safety feature.

Abstract: A method and apparatus for cleaning and drying semiconductor wafers wherein the wafers may be stored in a wet environment until the cleaning step and wherein, after drying, the wafers are substantially isolated from the remainder of the apparatus and the workplace environment to prevent or at least substantially eliminate the recontamination of the wafer surface. The wafers are removed one at a time from an incoming storage bath and are transported to a cleaning station where they are cleaned and are then transported to a drying station. After being dried the wafers are transported to an output station where they are loaded into a portable enclosure member which substantially isolates the wafers in the enclosure from further contamination. Further, means is provided for introducing clean air into the drying station and venting at least a portion of the air through the cleaning station while at the same time substantially precluding the escape of air into the output station enclosure member.

Abstract: A method of coating a container (1) including a structure defining an aperture comprises the steps of supporting the container (1) by the said structure, causing the container (1) to rotate about an axis thereof, causing the rotating container (1) to translate across the surface of a liquid coating composition (7) a portion of the container being immersed in the composition, and causing the composition to solidify upon the surface of the container. The method is particularly applicable to coating plastics bottles.

Abstract: An unscrambler, to which lightweight cup- or bowl-shaped articles such as the bottoms for plastic bottles or caps for aerosol containers, are fed prior to delivery to another, e.g. a bottle-making or cap-applying machine, for which they must all be presented right-way-up, and which are likely to become "stacked" when scrambled together, comprises a shallow, rotating dish reservoir which can be very big, e.g. up to or even more than 30 feet (10 meters) across, but which can be suspended from a roof or ceiling so as not to take up floor space. The dish has an inclined rim with an outer ledge, the articles being blown up the rim onto the ledge by an air current which puts them on the ledge right-way-up. Any articles that are stacked or not aligned properly on the ledge are removed by further air jets or mechanically.

Abstract: The disclosure relates to novel luliberin analogues which possess luliberin agonist activity, to processes for their manufacture and to compositions containing them. Typical of the peptides disclosed is ##STR1## in which A is D-Phe, D-Tyr(Me) or D-Ser(Bu.sup.t).