Abstract: A lightweight applicator system is provided for efficient extrusive dispensing of work material from a cartridge. A body of the system includes handle and cartridge frame portions. The handle portion defines a hub structure, which includes at least first and second retention structures. The cartridge frame portion includes a cage member configured for receiving a cartridge of work material, and is releasably coupled to the hub structure in revolvable manner First and second accessory tools are coupled respectively to the first and second retention structures in detachable manner A drive portion is operably coupled to the body, and includes a drive member passing displaceably into the cartridge frame portion for forcing extrusion of work material therefrom. The handle and cartridge frame portions of the body are formed of one or more predetermined nonmetallic materials.

Abstract: An applicator apparatus is provided for extrusively dispensing work material from a containment vessel, A base portion includes a handle and a control member. A cage portion coupled to the base portion defines a receiving compartment for at least one containment vessel. The cage portion is provided with a proximate end disposed adjacent the base portion and an intermediate section extending longitudinally therefrom to a distal end. A drive portion coupled to the base portion is actuated responsive to the control member for driving extrusion of the work material from the containment vessel. A clasp portion displaceably coupled to the cage portion is displaceable relative to the cage portion between first and second positions, where the second position is disposed along the intermediate section of the cage portion. The clasp portion forms a cuff about the receiving compartment of the cage portion for laterally retaining the containment vessel received therein.

Abstract: An applicator system for extrusive dispensing of work material from a flexible pre-charged portion of a cartridge unit is provided. The system comprises a body portion having an actuator and a housing coupled thereto. The housing includes a cartridge bay and an arresting member displaceably coupled thereto. The cartridge bay is configured to receive the cartridge unit and defines at least one containment compartment for receiving the pre-charged cartridge. The arresting member is displaceable between open and closed configurations for releasably retaining the cartridge unit. The actuator, coupled to the housing in communication with the cartridge bay, includes a drive member engaging the pre-charged cartridge within the containment compartment. The body includes a handle and an activation member coupled thereto.

Abstract: A combination tool apparatus selectively stows and deploys a plurality of variously configured implements for spreading materials. A housing defines a coupling end portion and includes first and second plate members extending longitudinally from the coupling end portion to define a stowage compartment therebetween. A blade set includes a plurality of blade members respectively defining spreading portions of various configuration. Each of the blade members is angularly displaceable between stowed and deployed positions with respect to the housing. When stowed, each blade member is disposed substantially within the stowage compartment of the housing. When deployed, each blade member has at least a portion extending outward from the stowage compartment. A coupling member disposed at the coupling end portion of the housing is pivotally coupled to the blade members for angular displacement thereabout between the stowed and deployed positions. The blade members are biased to remain in the stowed position.

Abstract: An applicator system for extrusive dispensing of work material from a flexible pre-charged portion of a cartridge unit is provided. The system comprises a body portion having an actuator and a housing coupled thereto. The housing includes a cartridge bay and an arresting member displaceably coupled thereto. The cartridge bay is configured to receive the cartridge unit and defines at least one containment compartment for receiving the pre-charged cartridge. The arresting member is displaceable between open and closed configurations for releasably retaining the cartridge unit. The actuator, coupled to the housing in communication with the cartridge bay, includes a drive member engaging the pre-charged cartridge within the containment compartment. The body includes a handle and an activation member coupled thereto.

Abstract: The present invention is directed to modulators of indoleamine 2,3-dioxygenase (IDO), as well as pharmaceutical compositions containing the same and methods for the treatment of IDO-associated diseases.

Abstract: A reduced sucrose cookie dough is provided comprising a Saccharide System. The Saccharide System comprises a crystalline sugar alcohol comprising at least one member selected from the group consisting of crystalline maltitol, -crystalline lactitol, and crystalline isomalt and at least one member selected from the group consisting of a liquid sugar alcohol and a long chain sugar complex. The Saccharide System has a Collective Solubility that is within about 20% of the solubility of sucrose in the dough. The cookie dough has a sucrose content of less than 0.5 grams per serving size. Methods of making the cookie dough are also provided.

Abstract: Shelf stable meal kits for slow cooker applications, the meal kits including a dehydrated vegetable product characterized by having an exterior surface composed of a hardened, closed cell structure. The invention further provides shelf stable meal kits for slow cooker applications, the meal kits including a dehydrated vegetable product having a vitreous like material on 25% or more of the surface area of the vegetable product. Further provided are shelf stable meal kits for slow cooker applications that include a dehydrated vegetable product having a stabilizing amount of a stabilizer. Methods for rehydrating dehydrated vegetables, as well as methods for preparing meal kits for slow cooker applications are also provided.

Abstract: A system and method is provided for assisting a human document annotator in recording semantic judgments about the contents of sample electronic documents. A system administrator first configures and stores a document annotation definition at a server computer, providing a precise and consistent structure for annotating documents and portions of documents. Documents intended to serve as sample documents for pattern matching against unknown documents are collected and stored at the server computer. A human annotator located at a client computer connected by a net-work to the server computer requests a display of a sample document to be annotated. A document is transmitted in an annotatable form from the server computer to the client computer. The human document annotator reviews the annotatable document, records semantic judgments about the document using interactive controls displayed with the document, and transmits a set of selected annotation values to the server computer.

Abstract: A hand held tool is provided with a handle, a ratcheting mechanism connected to the handle, and a quick release bit coupling device connected to the ratcheting mechanism.

Abstract: A hand held tool is provided with a handle, a ratcheting mechanism connected to the handle, and a quick release bit coupling device connected to the ratcheting mechanism.