Abstract: A turbine engine includes a compressor section, a combustion section, and a turbine section, and an airfoil with an outer wall defining a pressure side and a suction side and extending between a leading edge and a trailing edge to define a mean camber line. A first thickness is defined between the pressure side and the suction side at a first location along the mean camber line.

Abstract: An aircraft engine is provided. The aircraft engine includes a compressor section having a compressor. A turbine section is downstream of the compressor section. The turbine section includes a turbine having turbine blades arranged in counter rotating stages. The aircraft engine further includes one or more fluid supply lines and a fuel cell assembly fluidly coupled to the one or more fluid supply lines for receiving one or more input fluids. The fuel cell assembly is in fluid communication with the turbine section to provide one or more output products to the turbine section. The aircraft engine further includes a heat exchanger in fluid communication with the turbine downstream of the counter rotating stages of turbine blades to receive exhaust gases from the turbine. The heat exchanger is thermally coupled to the one or more fluid supply lines of the fuel cell assembly.

Abstract: A turbine engine includes a compressor section, a combustion section, and a turbine section, and an airfoil with an outer wall defining a pressure side and a suction side and extending between a leading edge and a trailing edge to define a mean camber line. A first thickness is defined between the pressure side and the suction side at a first location along the mean camber line.

Abstract: Various embodiments of the present disclosure provide a multi-input multi-output energy charging system to generate hydrogen, provide baseload energy to a facility, and provide electrical power to charge electric vehicles (EV). In an embodiment, a charging system includes a solid oxide fuel cell (SOFC) system that generates electricity from one or more fuel inputs. One or more fuel inputs are renewable fuels. The charging system further includes a solid oxide electrolyzer cell (SOEC) system coupled to the SOFC system. The SOEC system generates hydrogen from the electricity received from the SOFC system and water input. The SOFC system facilitates the charging of an electric vehicle, storing charge in a battery, and providing electric power to a load from the generated electricity. The SOEC system facilitates refueling a hydrogen fuel cell vehicle from the generated hydrogen and storing the generated hydrogen in a hydrogen storage vessel.

Abstract: The monitoring and control of bioprocesses is provided. The present disclosure provides the ability to generate generic calibration models, independent of cell line, using inline Raman probes to monitor changes in glucose, lactate, glutamate, ammonium, viable cell concentration (VCC), total cell concentration (TCC) and product concentration. Calibration models were developed from cell culture using two different CHOK1SV GS-KO™ cell lines producing different monoclonal antibodies (mAbs). Developed predictive models, qualified using an independent CHOK1SV GS-KO™ cell line not used in calibration, measured changes in glucose, lactate, ammonium, VCC, and TCC with minor prediction errors over the course of cell culture with minimal cell line dependence. The development of these generic models allows the application of spectroscopic PAT techniques in a clinical manufacturing environment, where processes are typically run once or twice in GMP manufacturing based on a common platform process.

Abstract: Various embodiments of the present disclosure provide a multi-input multi-output energy charging system to generate hydrogen, provide baseload energy to a facility, and provide electrical power to charge electric vehicles (EV). In an embodiment, a charging system includes a solid oxide fuel cell (SOFC) system that generates electricity from one or more fuel inputs. One or more fuel inputs are renewable fuels. The charging system further includes a solid oxide electrolyzer cell (SOEC) system coupled to the SOFC system. The SOEC system generates hydrogen from the electricity received from the SOFC system and water input. The SOFC system facilitates the charging of an electric vehicle, storing charge in a battery, and providing electric power to a load from the generated electricity. The SOEC system facilitates refueling a hydrogen fuel cell vehicle from the generated hydrogen and storing the generated hydrogen in a hydrogen storage vessel.

Abstract: The monitoring and control of bioprocesses is provided. The present disclosure provides the ability to generate generic calibration models, independent of cell line, using inline Raman probes to monitor changes in glucose, lactate, glutamate, ammonium, viable cell concentration (VCC), total cell concentration (TCC) and product concentration. Calibration models were developed from cell culture using two different CHOK1SV GS-KO™ cell lines producing different monoclonal antibodies (mAbs). Developed predictive models, qualified using an independent CHOK1SV GS-KO™ cell line not used in calibration, measured changes in glucose, lactate, ammonium, VCC, and TCC with minor prediction errors over the course of cell culture with minimal cell line dependence. The development of these generic models allows the application of spectroscopic PAT techniques in a clinical manufacturing environment, where processes are typically run once or twice in GMP manufacturing based on a common platform process.

Abstract: Systems and methods identify and trigger actions to improve performance in a role in an organization. A server computer receives input data associated with a performance of a target entity in a role in an organization from a remote device. The server computer also receives, via input to a Graphical User Interface (GUI), a set of weights for a respective set of skills for the role. The server computer computes a metric based on the input data and the weights, the metric representing the performance in the role for the target entity. The server computer identifies an action likely to improve the metric and triggers the action.

Abstract: Circuits for measuring a leakage current of one or more capacitors coupled to a power supply line that powers an apparatus, such as a storage device, are disclosed. In one embodiment, the circuit includes first and second resistors between the power supply line, and first and second respective switches to ground. A controller may charge the voltage line to a first voltage. Thereafter, the controller discharges the first voltage to a second voltage via the first resistor during a first identified time. After recharging the voltage line, the controller then discharge the first voltage to the second voltage via at least the second resistor during a second identified time. The controller determines the parasitic resistance using the first and second identified times, and then the leakage current from the parasitic resistance.

Abstract: Circuits for measuring a leakage current of one or more capacitors coupled to a power supply line that powers an apparatus, such as a storage device, are disclosed. In one embodiment, the circuit includes first and second resistors between the power supply line, and first and second respective switches to ground. A controller may charge the voltage line to a first voltage. Thereafter, the controller discharges the first voltage to a second voltage via the first resistor during a first identified time. After recharging the voltage line, the controller then discharge the first voltage to the second voltage via at least the second resistor during a second identified time. The controller determines the parasitic resistance using the first and second identified times, and then the leakage current from the parasitic resistance.

Abstract: The monitoring and control of bioprocesses is provided. The present disclosure provides the ability to generate generic calibration models, independent of cell line, using inline Raman probes to monitor changes in glucose, lactate, glutamate, ammonium, viable cell concentration (VCC), total cell concentration (TCC) and product concentration. Calibration models were developed from cell culture using two different CHOK1SV GS-KO™ cell lines producing different monoclonal antibodies (mAbs). Developed predictive models, qualified using an independent CHOK1SV GS-KO™ cell line not used in calibration, measured changes in glucose, lactate, ammonium, VCC, and TCC with minor prediction errors over the course of cell culture with minimal cell line dependence. The development of these generic models allows the application of spectroscopic PAT techniques in a clinical manufacturing environment, where processes are typically run once or twice in GMP manufacturing based on a common platform process.

Abstract: The present disclosure provides methods for improving batch-to-batch consistency of proteins produced by eukaryotic cells, as well as proteins produced thereby.