Abstract: In some embodiments, the present disclosure relates to a system that includes an insertion tool and a drill guide. The insertion tool includes a body with a distal portion and a distal end. The body has a first engagement feature extending longitudinally along the distal portion and two arms extending longitudinally from the distal end of the body. The drill guide includes two bores and an open faced channel therebetween. The open faced channel includes a second engagement feature slidably engageable with the first engagement feature on the body of the insertion tool. The two bores are adapted for the disposal of a fastener driver tool therethrough.

Abstract: Aspects of the present disclosure include methods and systems for receiving a first image, amplifying a luminous intensity of the first image to generate a second image, digitally capturing the second image, identifying a first time associated with receiving the first image or capturing the second image, acquiring spatial information of the imaging system, identifying a second time associated with acquiring the spatial information, associating the second image with the spatial information based on the first time being substantially contemporaneous with the second time, and generating at least one of a position or an orientation of the imaging system based on the second image and the spatial information.

Abstract: Compositions for the treatment of some orphan diseases and oral mucosal ulcers, many with similarities in terms of their anti-inflammatory and anti-oxidative activities, but also multiple differences in their observed abilities that can be combined to challenge the current, underlying pathophysiology. The orphan diseases of interest are Dupuytren's Contracture, Peyronie's Disease, Scleroderma, Raynaud's (or Renaud's) Phenomenon, chemotherapy/radiation induced oral mucosal ulceration, and aphthous ulcers; and more frequent skin issues of skin damage from cuts, abrasions, and burns; aging skin changes, and toe nail fungus. These can be treated with the disclosed compositions with the proper combination and alteration of ingredients inclusive of alpha-pinene, an aloe vera preparation, and a shea butter preparation. A process for preparation of such ingredients in a water-in-oil emulsion is described herein.

Abstract: In some embodiments, the present disclosure relates to a system that includes an insertion tool and a drill guide. The insertion tool includes a body with a distal portion and a distal end. The body has a first engagement feature extending longitudinally along the distal portion and two arms extending longitudinally from the distal end of the body. The drill guide includes two bores and an open faced channel therebetween. The open faced channel includes a second engagement feature slidably engageable with the first engagement feature on the body of the insertion tool. The two bores are adapted for the disposal of a fastener driver tool therethrough.

Abstract: In some embodiments, the present disclosure relates to a system that includes an insertion tool and a drill guide. The insertion tool includes a body with a distal portion and a distal end. The body has a first engagement feature extending longitudinally along the distal portion and two arms extending longitudinally from the distal end of the body. The drill guide includes two bores and an open faced channel therebetween. The open faced channel includes a second engagement feature slidably engageable with the first engagement feature on the body of the insertion tool. The two bores are adapted for the disposal of a fastener driver tool therethrough.

Abstract: A surgical instrument includes a body having a proximal end and a distal end and defining a lumen extending from the proximal end to the distal end along an axis, the distal end configured to abut an implant, and an anchor rod disposable within the lumen of the body for contacting the implant to secure the implant at the distal end of the body. When the anchor rod is disposed within the lumen of the body in a working configuration, the anchor rod is connected to the body at the proximal end of the body and at the distal end of the body to substantially fix the anchor rod from moving along the axis of the lumen. The body includes a handle, a shaft extending distally from the handle, and a torque limiting mechanism.

Abstract: Compositions for the treatment of some orphan diseases and oral mucosal ulcers, many with similarities in terms of their anti-inflammatory and anti-oxidative activities, but also multiple differences in their observed abilities that can be combined to challenge the current, underlying pathophysiology. The orphan diseases of interest are Dupuytren's Contracture, Peyronie's Disease, Scleroderma, Raynaud's (or Renaud's) Phenomenon, chemotherapy/radiation induced oral mucosal ulceration, and aphthous ulcers; and more frequent skin issues of skin damage from cuts, abrasions, and burns; aging skin changes, and toe nail fungus. These can be treated with the disclosed compositions with the proper combination and alteration of ingredients inclusive of alpha-pinene, an aloe vera preparation, and a shea butter preparation. A process for preparation of such ingredients in a water-in-oil emulsion is described herein.

Abstract: In some embodiments, the present disclosure relates to a system that includes an insertion tool and a drill guide. The insertion tool includes a body with a distal portion and a distal end. The body has a first engagement feature extending longitudinally along the distal portion and two arms extending longitudinally from the distal end of the body. The drill guide includes two bores and an open faced channel therebetween. The open faced channel includes a second engagement feature slidably engageable with the first engagement feature on the body of the insertion tool. The two bores are adapted for the disposal of a fastener driver tool therethrough.

Abstract: A surgical instrument includes a body having a proximal end and a distal end and defining a lumen extending from the proximal end to the distal end along an axis, the distal end configured to abut an implant, and an anchor rod disposable within the lumen of the body for contacting the implant to secure the implant at the distal end of the body. When the anchor rod is disposed within the lumen of the body in a working configuration, the anchor rod is connected to the body at the proximal end of the body and at the distal end of the body to substantially fix the anchor rod from moving along the axis of the lumen. The body includes a handle, a shaft extending distally from the handle, and a torque limiting mechanism.