Abstract: Methods for identifying biosynthetic gene clusters that include genes for producing compounds that interact with specific target proteins are disclosed. Some methods relate to bioinformatics methods for identifying and/or prioritizing biosynthetic gene clusters. Related systems, components, and tools for the identification and expression of such gene clusters are also disclosed.

Abstract: In some embodiments, an optical communication system may include an optical source, a modulator, and a photoreceiver. The optical source may be configured to generate a beam comprising a series of light pulses each having a duration of less than 100 picoseconds. The photoreceiver may have a detection window duration of less than 1 nanosecond. When a first pulse travels through a variably refractive medium, photons in the first pulse may be refracted to travel along different ray paths to arrive at the photoreceiver according to a temporal distribution curve. A full width at half maximum (FWHM) value of the temporal distribution curve may be at least three times as large as a coherence time value of the first pulse, and the detection window of the photoreceiver may be at least six times as large as the FWHM value of the temporal distribution curve.

Abstract: An object is to provide an information providing system and an information providing method in which an information providing device can provide information personalized for a user without an input of identification information of the user into the information providing device. A server device receives, from a terminal device that has acquired device identification information identifying the information providing device, the device identification information and user identification information identifying a user. The server device transmits information for the user identified by the user identification information to the information providing device identified by the device identification information. The information providing device receives the information for the user. The information providing device provides information based on the information for the user.

Abstract: Methods for forming a coated component, along with the resulting coated components, are provided. The method may include forming a silicon-based bond coating on a surface of a substrate and forming a barrier coating on the silicon-based bond coating. The silicon-based bond coating comprises columnar grains of crystalline silicon. Chemical vapor depositing (CVD) may be used to form the silicon-based bond coating through CVD of a silicon-containing precursor at a deposition temperature and deposition pressure that causes crystallization of the silicon material during the deposition of the silicon-based bond coating. The silicon-containing precursor may be silane, monochlorosilane, dichlorosilane, and/or trichlorosilane.

Abstract: An object is to provide an information providing system and an information providing method in which an information providing device can provide information personalized for a user without an input of identification information of the user into the information providing device. A server device receives, from a terminal device that has acquired device identification information identifying the information providing device, the device identification information and user identification information identifying a user. The server device transmits information for the user identified by the user identification information to the information providing device identified by the device identification information. The information providing device receives the information for the user. The information providing device provides information based on the information for the user.

Abstract: A coated component, along with methods of its formation and use, is provided. The coated component includes a substrate having a surface; a silicon-based bond coating on the surface of the substrate; and a barrier coating on the silicon-based bond coating. The silicon-based bond coating comprises amorphous silicon phase having grains of crystalline silicon (e.g., having an average size of about 0.03 ?m to about 3 ?m) distributed therein. The amorphous silicon phase may be formed of pure silicon metal, or may be formed from silicon metal with boron, oxygen, and/or nitrogen dispersed therein.

Abstract: Methods for forming a coated component, along with the resulting coated components, are provided. The method may include forming a silicon-based bond coating on a surface of a substrate and forming a barrier coating on the silicon-based bond coating. The silicon-based bond coating comprises columnar grains of crystalline silicon. Chemical vapor depositing (CVD) may be used to form the silicon-based bond coating through CVD of a silicon-containing precursor at a deposition temperature and deposition pressure that causes crystallization of the silicon material during the deposition of the silicon-based bond coating. The silicon-containing precursor may be silane, monochlorosilane, dichlorosilane, and/or trichlorosilane.

Abstract: Methods and systems of displaying flow-volume loops of a patient and variability of the flow-volume loops across measured breaths are disclosed. The methods comprise obtaining a physiological dataset of the patient on a data acquisition device, applying a smoothing and curve fitting algorithm to the physiological dataset on a processing device to obtain real-time volume and flow data at a plurality of time instances, applying a visualization algorithm on the processing device to the volume and flow data to create a series of flow-volume loops based on the volume and flow data, and outputting a plot of the flow-volume loops on a display device to aid evaluation or diagnosis of the patient.

Abstract: A method of evaluating a shale source rock formation comprising: determining in situ partial pressures of a light hydrocarbon utilizing a downhole Raman tool and producing a map of spatial and vertical variations of the in situ partial pressures of the light hydrocarbon in the shale source rock formation.

Abstract: A method of evaluating a shale source rock formation comprising: determining in situ partial pressures of a light hydrocarbon utilizing a downhole Raman tool and producing a map of spatial and vertical variations of the in situ partial pressures of the light hydrocarbon in the shale source rock formation.

Abstract: Systems and methods for computerized risk screening are provided. A plurality of facilities are identified for analysis of risk at each facility in the plurality of facilities. For each facility in the plurality of facilities, an answer set to a questionnaire is received. The answer set includes answers to questions for analysis of the risk at the facility. For each facility in the plurality of facilities, a predicted risk level of the risk at the facility is determined based on the answer set. A visual interface is provided. The visual interface includes: (i) a list of at least a portion of the facilities from among the plurality of facilities, (ii) a visual representation of at least one facility from among the plurality of facilities, and (iii) a visual indication of the predicted risk level of the risk for the at least one facility from among the plurality of facilities.

Abstract: A computer processor driven system and method capable of identifying and constructing representations of hazardous areas. The hazardous area classification system has one or more processors, and a computer readable medium containing instructions that, when executed, cause the one or more processors to perform the steps of determining a position of a hazardous area for a predetermined location using a calculation based on a plurality of parameters, and generating a representation of the hazardous area.

Abstract: A fire and gas detector placement system and method comprises one or more computer processors; and a non-transitory computer readable medium. The non-transitory computer readable medium contains instructions that, when executed, cause the one or more processors to perform the steps of identifying a position of at least one fire and gas detector in a premises using a calculation based on a plurality of parameters; and generating a 3-dimensional representation of the premises including the position of the at least one fire and gas detector.

Abstract: Articles coated via a plasma spray process, and methods for making such articles, are presented. For example, one embodiment is an article comprising a substrate comprising a top surface and a channel disposed in the substrate. The channel is defined by an internal channel surface disposed beneath the top surface and having a terminal end at an orifice at the top surface. A coating is disposed on the top surface and on at least a portion of the internal channel surface. A coating thickness at any point on the internal channel surface is less than a nominal coating thickness on the top surface, and the coating comprises a plurality of at least partially melted and solidified particles.

Abstract: Articles coated via a plasma spray process, and methods for making such articles, are presented. For example, one embodiment is an article comprising a substrate comprising a top surface and a channel disposed in the substrate. The channel is defined by an internal channel surface disposed beneath the top surface and having a terminal end at an orifice at the top surface. A coating is disposed on the top surface and on at least a portion of the internal channel surface. A coating thickness at any point on the internal channel surface is less than a nominal coating thickness on the top surface, and the coating comprises a plurality of at least partially melted and solidified particles.

Abstract: Articles coated via a plasma spray process, and methods for making such articles, are presented. For example, one embodiment is an article comprising a substrate comprising a top surface and a channel disposed in the substrate. The channel is defined by an internal channel surface disposed beneath the top surface and having a terminal end at an orifice at the top surface. A coating is disposed on the top surface and on at least a portion of the internal channel surface. A coating thickness at any point on the internal channel surface is less than a nominal coating thickness on the top surface, and the coating comprises a plurality of at least partially melted and solidified particles.

Abstract: An apparatus for providing a vacuum coating to a workpiece, including: a coating chamber containing a coating material, with the coating chamber being operable at an elevated temperature and a sub-atmospheric pressure; an electron beam gun projecting an electron beam into the coating chamber and onto the coating material, where the electron beam gun is operable to melt the coating material and to evaporate molten coating material; and, a mechanism for supporting manipulating the workpiece in the coating chamber. The supporting mechanism further includes: a coupling device for retaining the workpiece; a joint connected to the coupling device enabling movement of the workpiece in all directions; an intermediate member connecting the coupling device and the joint; and, a device connected to the intermediate member for moving the workpiece in a designated vertical plane.

Abstract: A computer processor driven system and method capable of identifying and constructing representations of hazardous areas. The hazardous area classification system has one or more processors, and a computer readable medium containing instructions that, when executed, cause the one or more processors to perform the steps of determining a position of a hazardous area for a predetermined location using a calculation based on a plurality of parameters, and generating a representation of the hazardous area.

Abstract: Articles coated via a plasma spray process, and methods for making such articles, are presented. For example, one embodiment is an article comprising a substrate comprising a top surface and a channel disposed in the substrate. The channel is defined by an internal channel surface disposed beneath the top surface and having a terminal end at an orifice at the top surface. A coating is disposed on the top surface and on at least a portion of the internal channel surface. A coating thickness at any point on the internal channel surface is less than a nominal coating thickness on the top surface, and the coating comprises a plurality of at least partially melted and solidified particles.